Infinium MethylationEPIC BeadChip Kit

NOTICE OF INTENT TO SOLE-SOURCE This contract action is for the acquisition of supplies for which the Government intends to solicit and negotiate with only one source under the authority and procedures of Federal Acquisition Regulation (FAR) Subpart 13.106-1(b). The National Institute of Environmental Health Sciences (NIEHS), Office of Acquisitions (OA) intends to award a single source purchase order to Illumina Inc., 5200 Illumina Way, San Diego, CA 92122, for the acquisition of Infinium MethylationEPIC BeadChip Kit (96 samples). The Infinium MethylationEPIC BeadChip ensures high quality genome-wide measurements of DNA methylation and enables measurements in small quantities of tissue. The need exists to purchase this reagent to achieve and maintain consistency with existing lab equipment and project goals. Illumina Inc. is the sole manufacturer and distributor of this product. The associated North American Industrial Classification System (NAICS) code for this procurement is 325413 "In-Vitro Diagnostic Substance Manufacturing". Its associated Small Business Size Standard is 1,250 Employees. The Environmental Epigenomics group is working to identify adverse effects from tobacco smoke and requires 288 Illumina EPIC methylation array reagents (expendable supplies) in order to evaluate DNA methylation levels as biomarkers of disease. Line Item 0001 - WG-317-1003 - Infinium Methylation EPIC 96samples: Qty. 3 (Infinium Methylation array targeting >850k methylated CpGs in promoter, gene body, and enhancer regions for genome wide methylation studies For 96 samples, 12 BeadChips.) NIEHS will solicit and negotiate directly with Illumina Inc., and no solicitation will be issued. This notice of intent is not a request for competitive proposals or quotations; however, if an interested party believes they can meet the above requirement, all responsible sources may submit a quotation which shall be considered by the agency. The quotation must be submitted in writing and must contain material in sufficient detail to allow the Government to determine if the party can perform the requirement. Offerors must have an active registration in the System for Award Management (SAM) www.sam.gov. A determination by the Government not to compete this proposed requirement based on responses to this notice is solely within the discretion of the Government. All interested parties must express their interest or quotation in writing via email to hugo.alcantara@nih.gov within ten (10) days after the date of publication of this notice. No faxed documents will be accepted. If no responsive statements or quotations are received within ten (10) days, an award will be made to Illumina Inc.