This Combined Synopsis/Solicitation opportunity from Department Of Health And Human Services was posted on September 19, 2025. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

Top

Integration platform of PATs and digital twin for Lyophilization

Closed

75F40125Q00458Federal

Submission Closed09/23/2025, 06:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

Active Opportunities Like This One

NAICS: 541519

New

Federal

Classified Data Sanitization ServicesThis subcontract involves providing secure erasure and sanitization services for classified data supporting Air Force Sustainment Center F-15 DMS projects. The scope of work focuses on the sanitization of Advanced Display Core Processors and Mission Cartridges using NSA-approved equipment to ensure units are ready for non-classified repair or disposal. The project is managed under the Department of Defense and will be performed in Warner Robins. Due to the nature of the classified data, the contractor must maintain a Facility Security Clearance and ensure all assigned personnel hold the necessary security clearances.

POSTED

DEADLINE

Technical Support Services (Help Desk)This subcontract for Technical Support Services (Help Desk) provides essential technical assistance to prime contractors working on Navy Recruiting Command projects. The scope of work includes troubleshooting access issues, offering technical guidance on platform utilization, and managing user accounts and credentials. These services are delivered during normal business hours through the use of customer support ticketing systems to ensure consistent platform uptime and ongoing operational support. Managed under NAICS code 541519 for the Department of Defense and Navsup Flt Logistics Ctr Norfolk, the work is performed in Millington, Tennessee. The opportunity was posted on October 21, 2026, with a response deadline of October 23, 2026.

Navsup Flt Logistics Ctr Norfolk

POSTED

DEADLINE

COMSEC Accountability & OperationsThe COMSEC Accountability and Operations subcontract, issued by the Department of Defense IT Contracting Division, focuses on managing communications security operations and accountability for prime contractors on USAWHC G-6 projects. Based in Fort Bragg, the role involves performing monthly and bi-annual inventories of controlled cryptographic items, managing hand-receipts, and conducting financial liability investigations regarding property loss to ensure accurate records and inventories. Qualified personnel must possess a Secret security clearance and have completed Department of War-mandated Key Management Infrastructure and COMSEC training. This opportunity falls under NAICS code 541519, with a response deadline set for November 2, 2026.

It Contracting Division - PL83

POSTED

DEADLINE

Full-Spectrum Cybersecurity & RMFThis subcontract opportunity, titled Full-Spectrum Cybersecurity and RMF, supports prime contractors on USAWHC G-6 projects within the Department of Defense. The scope of work focuses on cybersecurity sustainment, risk management, and incident response, specifically requiring the performance of Risk Management Framework and Authority to Operate sustainment. Contractors will utilize vulnerability scanners and compliance tools to manage vulnerabilities and provide essential remediation reports to maintain a valid ATO. The project is based in Fort Bragg and requires personnel to hold either a Secret or Top Secret security clearance. Interested parties should note the response deadline of November 2, 2026. The contract falls under NAICS code 541519 and is managed through the IT Contracting Division of the Department of Defense.

It Contracting Division - PL83

POSTED

DEADLINE

U.S. Government Software Support ServicesThis subcontract provides manufacturer-level technical support for Rustici Content Controller software to assist prime contractors working on the U.S. Coast Guard CG-OWL enterprise learning management system projects. Managed under the Department of Homeland Security's Special Mission Training Center, the contract ensures the operational capability of the CG-OWL system by utilizing Rustici Content Controller support infrastructure and delivering ongoing technical support entitlements. The services are governed by Rustici Software, LLC commercial support terms for U.S. Government customers and are categorized under NAICS code 541519. Performance for this engagement is centered in Norfolk, Virginia.

Special Mission Training Center (smtc)

POSTED

DEADLINE

Cyber Security Engineering and Risk Management Framework Support

Solicitation # W91CRB-26-B-A006

Solicitation W91CRB-26-B-A006 is a firm-fixed-price commercial services contract issued by the Army Contracting Command - Aberdeen Proving Ground for Cybersecurity Engineering and DoD Risk Management Framework (RMF) Support Services. The contractor will provide all personnel, equipment, and supervision necessary to establish and maintain Authority to Operate (ATO) and RMF compliance for the Aberdeen Test Center (ATC) Local Area Network, Logically Isolated Network, Secure Test Environment, and Test and Evaluation Network. The period of performance spans from November 23, 2026, to November 22, 2031, consisting of a base year and four 12-month option years. This procurement is set aside for small businesses, with a specific preference for HUBZone and Women-Owned Small Businesses. Award will be made to the lowest-priced, responsive, and responsible bidder based on a Total Evaluated Price calculation. Key personnel requirements include a Senior IT Solutions Architect with CISSP certification and 10 years of RMF experience, as well as other IT professionals with CASP+ or equivalent certifications. Security requirements are stringent, requiring a Secret Facility Security Clearance at the time of bid submission, with specific personnel requiring Top Secret clearances for surge support and access to SIPRNet and Special Access Programs. The scope of work involves RMF lifecycle activities, including system categorization, security control implementation, and auditing for Secret and below environments, while following Intelligence Community Directive 503 for Top Secret requirements. Additional responsibilities include engineering and configuration support, incident management, and the implementation of a Quality Control Program within 30 days of award. Bidders must submit a single electronic volume containing administrative documents, a completed pricing schedule, and security compliance documentation by the specified deadline.

POSTED

DEADLINE

DA10--Reviewed and Ready VISN Rad PACS - HL7 Conversion to DAS-SPOE

Solicitation # 36C25227Q0065

The Department of Veterans Affairs, through the VA Great Lakes Acquisition Center, intends to award a sole source, firm fixed price, one-time service contract to Change Healthcare Technologies/Optum. The scope of work involves the conversion to a DAS-SPOE HL7 interface for the CHC RAD PACS service. This procurement is conducted under the authority of 41 U.S.C. 1901 and FAR 12, based on the determination that Change Healthcare Technologies/Optum is the only responsible source capable of satisfying the requirements as they own and manufacture the necessary components and equipment already installed at the facility. The contractor is required to utilize certified authorized service technicians for the performance of these services. The project is categorized under NAICS code 541519 and will be performed within VISN 12. While this is a notice of intent for a sole source procurement, the government will consider capability statements from other firms that can demonstrate the ability to meet the requirements. Interested parties must submit detailed information regarding their products, services, and customer references via email in MS Word or Adobe PDF format to the contracting officer by 5:00 PM CST on October 23, 2026. The government maintains full discretion in determining whether to proceed with the sole source negotiation or to compete the procurement based on the responses received.

252-NETWORK Contract Office 12 (36C252)

POSTED

DEADLINE

United States Army Western Hemisphere Command (USAWHC) G-6 Information Technology Service Management Western Command and Control System (WCCS)

Solicitation # 832674525

The United States Army Western Hemisphere Command (USAWHC) G-6 is issuing a Sources Sought Notice under solicitation 832674525 to identify capable small and large businesses to provide comprehensive Information Technology Service Management (ITSM) support for the Western Command and Control System (WCCS). The scope of work involves delivering and sustaining critical command and control, Unified Communications, Audio/Visual, and enterprise IT capabilities. Key functional requirements include service desk and information management operations for over 1,000 users, data center and network operations, and full-spectrum cybersecurity, specifically Risk Management Framework and Authority to Operate sustainment, vulnerability management, and COMSEC accountability. Additionally, the contractor must provide knowledge management solutions using Microsoft 365, SharePoint Online, and the Power Platform. The anticipated period of performance begins February 1, 2027, with a one-year base period and four option years. Primary performance locations include Fort Liberty and Camp Mackall in North Carolina, Joint Base San Antonio in Texas, with limited support at Fort Hood and Aberdeen Proving Ground, and potential travel to regional Deployable Communications Element locations. All personnel must hold at least a Secret security clearance, with some positions requiring Top Secret clearance, and those supporting partner nations in the SOUTHCOM area of responsibility must be professionally fluent in Spanish and Portuguese. The government is seeking capabilities from various socio-economic categories, including 8(a), SDVOSB, HUBZone, and Woman-Owned Small Businesses, under NAICS 541519. Interested respondents must submit a capabilities statement of no more than five pages by November 2, 2026.

It Contracting Division - PL83

POSTED

DEADLINE

Regional OT Field Technician / Site LiaisonThis subcontract for a Regional OT Field Technician / Site Liaison involves providing on-site technical support and hardware connectivity for prime contractors working on Pakistan State Oil Company Limited projects. The scope of work is centered in Faisalabad, Keamari, and Machike, where the technician will manage physical access to control cabinets and server rooms, connect testing hardware to network ports, and monitor overall system stability during testing phases. The role requires strict adherence to oil and gas facility safety standards, necessitating site-specific HSE safety certifications. Key deliverables include the maintenance and delivery of site access logs. Interested parties should note the response deadline of November 4, 2026, for this specialized technical support engagement within Pakistan.

Pakistan State Oil Company Ltd

POSTED

DEADLINE

OT VAPT Specialist (Industrial Control Systems)This subcontract opportunity is for an OT VAPT Specialist to provide vulnerability assessments and penetration testing for prime contractors working on automation projects for Pakistan State Oil Company Limited. The scope of work involves conducting both passive and active discovery of operational technology assets, utilizing OT-safe tools for vulnerability scanning, and performing controlled penetration testing on critical infrastructure including PLCs, HMIs, and SCADA systems. The final deliverable is a comprehensive VAPT Report that includes detailed risk ratings and actionable remediation recommendations. Qualified candidates must hold professional certifications such as GICSP or CISSP. The project is based in Pakistan and is categorized under NAICS code 541519. Interested parties must submit their responses by the deadline of November 4, 2026.

Pakistan State Oil Company Ltd

POSTED

DEADLINE

Cybersecurity & Data Management ServicesThis subcontract for the U.S. Fish and Wildlife Service within the Department of the Interior focuses on providing cybersecurity implementation and comprehensive data management for grant recipients. The selected provider will be responsible for the gathering, storage, tracking, analysis, and publication of project data while ensuring all processes comply with federal data security standards. A primary objective of the contract is the delivery of a secure data management system and the creation of functional data dashboards using specialized cybersecurity software and secure storage systems. The opportunity is categorized under NAICS code 541519 and was posted on October 21, 2026. Interested parties must submit their responses by the deadline of January 15, 2027. This engagement ensures that critical project data is disaggregated, secured, and shared effectively to support the agency's mission.

US Fish And Wildlife Service

POSTED

DEADLINE

Cybersecurity & System Hardening SpecialistThis subcontract opportunity for a Cybersecurity and System Hardening Specialist supports prime contractors on projects for the State Corporation Commission of Virginia. The scope of work focuses on security architecture design and system hardening, specifically through the implementation of identity security, endpoint protection, secure data transmission, and encryption of data at rest. The selected provider will be responsible for ensuring all systems meet SOC 2 or ISO 00 compliance standards and establishing robust audit logging. Key deliverables include a fully hardened system environment, detailed security configuration reports, and established encryption protocols. The project is categorized under NAICS code 541519 and allows for performance at the supplier's site. Interested parties must submit their responses by November 20, 2026.

State Corporation Commission

POSTED

about 22 hours ago

DEADLINE

in about 1 month

AI Contract Overview

The contract involves the development and integration of a platform that combines Process Analytical Technologies (PATs) and a digital twin specifically for lyophilization processes. It is a sole-source solicitation issued by the FDA Office of Acquisitions and Grants Services, with the purpose of acquiring commercial products or services to enhance the FDA's capabilities in monitoring and optimizing lyophilization operations through advanced digital solutions. The solicitation was posted on September 19, 2025, with a response deadline of September 23, 2025, and is open to all qualified vendors without any set-aside restrictions. The NAICS code associated with this procurement is 541519, indicating a focus on other computer related services. Interested parties are directed to contact Lilibeth Deato via email or phone for further details, and additional information about the solicitation can be accessed through the provided link on SAM.gov. The contract aims to support the FDA's mission by leveraging innovative digital tools to improve process control and validation in pharmaceutical manufacturing, specifically in lyophilization, which is critical for ensuring drug stability and efficacy.

General Info

FDA seeks integrated PATs and digital twin platform for lyophilization process, proposals due September 2025.

Agency

Department Of Health And Human Services → FDA Office Of Acquisitions And Grants Services

NAICS

541519 - Other Computer Related Services

Place of Performance

MD, USA

Set-Aside

NONE

Documents

FDA RFQ 75F40125Q00458 - Integration platform of PATs and digital twin for Lyophilization

rfq

High

AI Contract Breakdown

Uniform Contract Format

Contract not broken down yet

CLEATUS splits the solicitation into Uniform Contract Format (UCF) sections: scope, pricing, deliverables, and evaluation criteria.

Timeline

1 update

PhaseClosed

PostedSep 19

Combined Synopsis

Notice updatedSep 19

Set-aside changed from No Set aside used to Total Small Business Set-Aside (FAR 19.5).

Response DeadlineSep 23

Deadline has passed

Submission Closed

09/23/2025, 06:00:00 PM UTC

Find active opportunities like this

Start your free trial to discover similar active contracts, track opportunities, and build proposals with AI assistance.

Organization & Contact Information

AgencyDepartment Of Health And Human Services → FDA Office Of Acquisitions And Grants Services

Contacts1 person available

OfficeRockville, MD, 20857, USA

Organization / AgencyDepartment Of Health And Human Services → FDA Office Of Acquisitions And Grants Services

Office AddressRockville, MD, 20857, USA

Contacts

Lilibeth Deato

contact@example.gov

+1 (555) 000-0000

Full Description

Integration platform of PATs and digital twin for Lyophilization This is a combined synopsis/solicitation for commercial products or commercial services prepared in accordance with the format in subpart 12.6, as supplemented with additional information included in this Request of Quotation. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued.