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This Combined Synopsis/Solicitation opportunity from Department Of Health And Human Services was posted on August 30, 2024. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

LABORATORY SERVICE FOR CUSTOM PURIFIED CDNA'S AND PROTEINS

Closed
NOI-NIAID-24-2226825Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541380
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Joliet Job Corps

POSTED

about 12 hours ago

DEADLINE

in about 16 hours

General Info

NAICS

541380 - Testing Laboratories and Services

Place of Performance

Bethesda, MD, 20892, USA

Set-Aside

NONE

Documents

0

No documents available

Documents will appear here when they are available.

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Timeline

PhaseClosed
Posted

Combined Synopsis

Response Deadline

Deadline has passed

Submission Closed

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health Niaid
Contacts2 people available
OfficeBETHESDA, MD, 20892, USA

Full Description

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This is a Notice of Intent, not a request for proposal. The National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (NIH) intends to negotiate on an other than full and open competition basis with Laboratories Nexelis Canada, Inc, located at 525 Boul Cartier O Laval, Qc H7V 3S8 Canada for the sequencing of custom purified CDNA's and proteins. The Laboratory of Infectious Diseases (LID) within the National Institute of Allergy and Infectious Diseases (NIAID) focuses on viral vaccine development, host immune response to viruses, and viral molecular biology and genetics. Major long-term programs are dedicated to understanding and preventing viral hepatitis, severe childhood respiratory diseases, and viral gastroenteritis. Newer programs focus on developing vaccines for pandemic influenza, West Nile virus, human metapneumovirus, and SARS-CoV'from basic research to clinical trials. The laboratory (the structural informatics unit) designs and studies the structure and epitopes display of influenza hemagglutinin antigens formulated into different mixtures of adjuvants to study influenza vaccines in terms of immunogenicity, biochemical and electron microscopic techniques. As such the purified codon-optimized cDNAs and hemagglutinin proteins will be used to carry out vaccine. Because high expression levels are needed the codon optimized cDNAs sequencing is needed to make hemagglutinin proteins for experimental studies. cDNAs and proteins from the vendor have been used by others in the field and have proven to be of sole unique high quality and allowed successful experiments and met the requirement of concentrated, purified, characterized cDNA and proteins for biochemical and animal studies. The statutory authority for this sole source requirement is 41 U.S.C. 1901 (a) (1) as implemented by FAR 13.106-1 only one responsible source and no other supply of service will satisfy agency requirements. THIS IS NOT A REQUEST FOR PROPOSAL. All responsible sources that could provide comparable services may submit a capability statement that will be considered. The documents must be submitted via the NIAID electronic Simplified Acquisition Submission System (eSASS) website at https://esass.nih.gov, (subject line to reference NOI-NIAID-24-2226825 by 12:00 pm eastern standard time September 6, 2024. All vendors must register in the eSASS system to submit a quotation. Instructions on how to register / submit quotes are included on the website. Late submissions shall be treated in accordance with the solicitation provision at FAR 52.212-1(f). All responsible sources may submit an offer that will be considered by this Agency.

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Solicitation # HHS-NIH-NIAID-BAA2026-1
The National Institute of Allergy and Infectious Diseases (NIAID) is soliciting proposals under Broad Agency Announcement HHS-NIH-NIAID-BAA2026-1 to advance the research and development of medical interventions for infectious diseases. This initiative focuses on three primary research areas: the development of needle-free vaccine candidates through early-phase clinical trials; the creation of safe and effective therapeutic candidates for serious infectious diseases, including those resistant to current antimicrobial therapy; and the innovation of in vitro diagnostic technology platforms capable of rapid, automated detection of a broad panel of priority viral pathogens. The program emphasizes alignment with NIH priorities regarding biosafety, biosecurity, and the use of non-animal testing methods. Proposals must be submitted electronically via the NIAID eCPS website by December 8, 2026, at 3:00 PM Eastern Time. Technical proposals are limited to 75 pages and will be evaluated by a peer review group based on technical merit, with the technical plan and personnel qualifications being of paramount consideration. Awards are not based on a common Statement of Work; instead, offerors must propose their own technical plans, milestones, and cost structures using a base and option period format. The resulting contracts will require an accounting system compliant with generally accepted accounting principles and will involve rigorous government inspection and acceptance based on the successful completion of critical milestones.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

12 days ago

DEADLINE

in about 2 months
View Details

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