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Limited Competition: Small Grant Program for NHLBI K01/K08/K23/K25 Recipients (R03 Clinical Trial Optional)

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RFA-HL-27-004Grant

Response Deadline11/07/2028, 05:00:00 AM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

AI Contract Overview

Notice of Funding Opportunity RFA-HL-27-004 is a limited competition solicitation from the National Institutes of Health and the National Heart, Lung, and Blood Institute. The program provides R03 small grant support to current or recently completed NHLBI K01, K08, K23, and K25 awardees to facilitate their transition to research independence. Eligible applicants may use the funding to expand current research objectives or initiate new studies emerging from their K award research. Current awardees are eligible to apply starting in the third year of their project period, while recently completed awardees may apply if the potential start date is within two years of their project end date. The R03 mechanism supports projects that can be completed within two years, with direct costs limited to 85,000 dollars per year. Applications are peer-reviewed based on significance, innovation, approach, investigator expertise, and environment, with a specific focus on how the work evolved from the K award and its potential to generate preliminary data for a subsequent R01-equivalent application. Applicants must maintain at least 40 percent protected research effort and provide a detailed plan and timeline for submitting future independent grant applications. Required documentation includes a summary of K award research progress, letters of support from mentors and institutional heads, and a data management and sharing plan. Eligible organizations include small businesses and for-profit entities, though non-domestic organizations are ineligible. The funding opportunity remains open for applications through November 7, 2028, with a final expiration date of November 8, 2028.

General Info

Small grants support NHLBI K01, K08, K23, K25 awardees’ research independence, due 11/7/2028.

Agency

Department Of Health And Human Services → National Institutes Of Health

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)View NAICS

Place of Performance

Not specified

Set-Aside

NONE

Documents

(1)

RFA-HL-27-004 Revised Full Announcement

HTML•28 pages•presolicitation

AI Contract Breakdown

Uniform Contract Format

Timeline

PhaseSolicitation

PostedMay 12

Solicitation

Response DeadlineNov 7

Submission deadline

Response Deadline

11/07/2028, 05:00:00 AM UTCin about 2 years

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Organization & Contact Information

AgencyDepartment Of Health And Human Services → National Institutes Of Health

Contacts1 person available

OfficeUSA

Organization / Agency

Department Of Health And Human Services → National Institutes Of Health

Office AddressUSA

Contacts

National Institutes of Health

contact@example.gov

+1 (555) 000-0000

Full Description

This is a Notice of Funding Opportunity (NOFO) for a Limited Competition that invites applications from eligible organizations to apply. Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the applications will be peer-reviewed, and only meritorious applications will be considered. The purpose of this NOFO is to solicit current or recently completed NHLBI K01, K08, K23, and K25 awardees for small grant support to expand their current research objectives or to branch out to a new study emerging from their K award research. This NOFO is intended to facilitate the transition to research independence for these NHLBI K awardees. Current NHLBI K01, K08, K23, and K25 awardees may apply for this R03 support starting in the third year of their K award Project Period. Recently completed NHLBI K01, K08, K23, and K25 award recipients are eligible to apply or resubmit A1 applications if the earliest potential R03 award start date is within two years of the end of their K award Project Period.The R03 grant mechanism supports research projects that can be completed within two years and with limited resources. These projects are expected to generate preliminary data to bolster a subsequent R01-equivalent application. Eligible projects include, but are not limited to, pilot or feasibility studies; proof of concept studies; secondary analysis of existing data; small, self-contained research projects; development of new research methodologies or technologies, or creation of novel experimental model systems.Applicants are required to maintain a minimum of 40% protected research effort during the R03 award period. This requirement can be fulfilled through a combination of effort on the proposed R03 project and other research projects, irrespective of funding source.For current and former K23 awardees, the research proposed in the R03 application may or may not include patient-oriented research.