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This Combined Synopsis/Solicitation opportunity from Department Of Health And Human Services was posted on March 30, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

MALDI-TOF Biotyper Sirius

Closed
75F40126R00030Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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SERVICE AGREEMENT FOR RAITH VOYAGER
Solicitation # N00173-27-Q-1301395177
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General Info

Agency

Department Of Health And Human Services → FDA Office Of Acq Grant Svcs

NAICS

334516 - Analytical Laboratory Instrument Manufacturing

Place of Performance

Summit Argo, IL, 60501, USA

Set-Aside

NONE

Documents

3

Attachment 2 - Pricing Sheet

XLSX, High priority: read this firstpricing-sheet
High

RFQ 75F40126R00030 MALDI-TOF Biotyper Sirius Purchase

PDF, High priority: read this firstrfq
High

SOW for FDA MALDI-TOF Biotyper Sirius one GP System Acquisition

PDF, High priority: read this firstsow
High

AI Contract Breakdown

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Timeline

PhaseClosed
Response Deadline

Deadline has passed

Posted

Combined Synopsis

Submission Closed

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → FDA Office Of Acq Grant Svcs
Contacts1 person available
OfficeRockville, MD, 20852, USA
Organization / AgencyDepartment Of Health And Human Services → FDA Office Of Acq Grant Svcs
Office AddressRockville, MD, 20852, USA
Contacts
Erika Crawford
contact@example.gov
+1 (555) 000-0000

Full Description

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The select agent laboratory at Moffett participates in the Laboratory Response Network (LRN) for detecting botulinum neurotoxins (BoNTs). Traditional mouse bioassays, though the gold standard, are costly, slow, and raise ethical concerns. Previously, DIG-ELISA kits were used for high-throughput screening to reduce animal use, but these kits are being phased out in favor of the Endopep-MS (Endopeptidase–Mass Spectrometry) assay.


Developed over 10 years by CDC’s Biological Mass Spectrometry Laboratory, the Endopep-MS assay detects BoNT activity on peptide substrates that mimic the toxin’s natural targets. This method eliminates animal testing and allows high-throughput analysis, supporting rapid response in large-scale events.


The FDA requires one (1) Bruker MALDI-TOF Biotyper Sirius one GP system to replace an obsolete instrument. The system must support Endopep-MS assays for detection, differentiation, and characterization of Clostridium botulinum neurotoxins, maintaining operational capability critical to mission readiness and public health protection.

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