This Solicitation opportunity from Government of Canada was posted on March 9, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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Measurement of Micronucleus Incidence

Closed

1000267742International

Submission Closed03/09/2026, 02:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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1 day ago

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in 30 days

General Info

Agency

Government of Canada → Department of Health

NAICS

541380 - Testing Laboratories and Services

Place of Performance

*Ottawa *National Capital Region (NCR), CAN

Set-Aside

NONE

Documents

1000267742 Amendment #1 - Measurement of Micronucleus Incidence

1 page · amendment

High

1000267742 - Measurement of Micronucleus Incidence

48 pages · rfp

High

1000267742 - Micronuclei Frequency Evaluation - Modification #1

4 pages · amendment

High

Solicitation 1000267742 - Évaluation de la fréquence des micronoyaux

48 pages · rfp

High

AI Contract Breakdown

Uniform Contract Format

Timeline

1 update

PhaseClosed

PostedFeb 16

Solicitation

Notice updatedMar 9

Response deadline time changed from 7:00 PM UTC to 2:00 PM UTC on Mar 9, 2026. The notice description changed. The point of contact changed.

Response DeadlineMar 9

Deadline has passed

Submission Closed

03/09/2026, 02:00:00 PM UTC

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Organization & Contact Information

AgencyGovernment of Canada → Department of Health

Contacts1 person available

OfficeN/A

Organization / AgencyGovernment of Canada → Department of Health

Office AddressN/A

Contacts

Sami NouhPoint of Contact

contact@example.gov

+1 (555) 000-0000

Full Description

Contract Period: From contract award until March 31, 2026 with two (2) one year option periods. 1. TITLE Measurement of Micronucleus Incidence in Urothelial and Buccal Epithelial Cells Collected from Wildland Firefighters 2. SCOPE 2.1. Introduction Firefighters have an increased risk of chronic cardiovascular diseases, respiratory diseases, and cancer. In 2024, the Government of Canada passed the Prevention and Treatment of Cancers Linked to Firefighting Act; one of the objectives is the establishment of a national framework whereby awareness about cancers linked to firefighter is increased. Early biomarkers of genotoxic effects, such as micronucleus (MN) incidence in targeted cell populations, can be used to monitor cancer risk (Fenech et al., 2020). More specifically, the presence of MN in bladder urothelial cells has been empirically and mechanistically linked to cancer (Arora et al., 2010; Espinoza et al., 2019). Similarly, MN in buccal (oral) epithelial cells have also been linked to an increased risk of cancer (Bolognesi et al., 2015). Health Canada (HC) is seeking a contractor to measure the incidence of MN in urothelial cells and buccal epithelial cells collected from wildland firefighters. The work is part of the deliverables outlined in an HC project entitled Genotoxic Effects as Early Biomarkers of Cancer Risk in Wildland Firefighters. The project is funded under the aforementioned national framework on cancers linked to firefighting. 2.2. Objectives of the Requirement The objective of the requirement is to measure the incidence of MN in urothelial cell samples and buccal epithelial cell samples collected from wildland firefighters engaged in active fire suppression. HC will first perform a small study that will utilize urine samples and mouth swab samples collected from 12 local individuals; these will serve as pilot samples to evaluate an in-house protocol for the preparation of samples derived from urine and buccal swabs. Subsequently, HC will collect 90 samples per fiscal year (FY) from wildland firefighters engaged in active fire suppression. Urothelial cells and buccal epithelial cells will be isolated from urine and buccal swabs, respectively, fixed, placed on glass microscope slides, and suitably stained for MN incidence determination. The MN incidence data will allow HC researchers Page 42 of 48 to address knowledge gaps pertaining to firefighter cancer risk; moreover, mitigation strategies to reduce risk.