This Government Contract opportunity from Department Of Health And Human Services was posted on June 22, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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NextSeq1000 to NextSeq2000 upgrade.

Closed

7571TE26Q00048Federal

Submission Closed06/26/2026, 06:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 334516

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252-NETWORK Contract Office 12 (36C252)

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AI Contract Overview

The Department of Health and Human Services, through the National Institutes of Health’s National Eye Institute, is seeking to procure a sole-source upgrade of its existing Government-owned Illumina NextSeq 1000 Sequencing System to NextSeq 2000 capability, exclusively from Illumina, Inc. This upgrade, identified by proprietary part number 20047256, is necessary to enhance sequencing flexibility and throughput by enabling support for all four flow cell types (P1–P4), including high-capacity P4 configurations capable of generating up to 1.8 billion paired reads per run. The work involves comprehensive conversion services, including hardware and software modifications, installation, testing, and technical validation—all of which must preserve full compatibility with existing Illumina reagents, workflows, and laboratory software environments. The National Eye Institute’s Neurobiology, Neurodegeneration and Repair Laboratory relies on this system for ongoing research, and the upgrade is critical to maintain operational continuity without disruption to validated protocols. Illumina, Inc. is the sole source authorized to perform this upgrade due to its proprietary nature, making competition impracticable under FAR 13.106-1(b)(1) and exempting the acquisition from full and open competition requirements under FAR Part 6. The procurement is being processed as a commercial items acquisition under FAR Part 12 as a fixed-price contract with an estimated performance period of one week. The work must be performed on-site at NIH Building 6, Room 328 in Maryland, with the contractor responsible for all travel, materials, labor, and equipment. Offerors are not required to hold security clearances, but all entities submitting a capability statement must be currently registered in SAM.gov to be eligible for award. Proposals must be submitted via email to Contract Specialist Mesfin Alemayehu no later than 2:00 p.m. EST on Friday, June 26, 2026, and must include sufficient technical documentation to demonstrate the ability to execute the upgrade and confirm system compatibility. No competitive evaluation factors or pricing details are provided, as this is a non-competitive acquisition justified solely by the proprietary nature of the upgrade. The Government reserves the right to use submitted information to assess potential competition but does not anticipate awarding to any other vendor.

General Info

Sole-source upgrade of NextSeq 1000 to NextSeq 2000 by Illumina for expanded capacity and workflow continuity in Maryland.

Agency

Department Of Health And Human Services → Office Of The Assistant Secretary For Administration (asa)View Agency

NAICS

334516 - Analytical Laboratory Instrument ManufacturingView NAICS

Place of Performance

MD, USA

Set-Aside

Documents

(1)

SOW for NextSeq1000 to NextSeq2000 Upgrade

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AI Contract Breakdown

Uniform Contract Format

Timeline

PhaseClosed

PostedJun 22

special-notice

Response DeadlineJun 26

Deadline has passed

Submission Closed

06/26/2026, 06:00:00 PM UTC

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Organization & Contact Information

AgencyDepartment Of Health And Human Services → Office Of The Assistant Secretary For Administration (asa)

Contacts2 people available

OfficeN/A

Organization / Agency

Department Of Health And Human Services → Office Of The Assistant Secretary For Administration (asa)

View Agency Profile

Office AddressN/A

Contacts

Mesfin Alemayehu

contact@example.gov

Vera Nordalm

contact@example.gov

Full Description

The Department of Health and Human Services (HHS), National Institutes of Health (NIH), National Eye Institute (NEI) plans to procure, on a sole source basis, the upgrade of an existing Illumina NextSeq 1000 Sequencing System to NextSeq 2000 capability from:

Illumina, Inc.
5200 Illumina Way
San Diego, CA 92122

The response close date of the notice for this requirement is in accordance with FAR 5.203(b). This acquisition will be processed under FAR Part 12 – Acquisition of Commercial Products and Commercial Services and will be made pursuant to the authority in FAR 13.106-1(b)(1) and is exempt from the requirements of FAR Part 6. The North American Industry Classification System (NAICS) code is 334516 – Analytical Laboratory Instrument Manufacturing.

The National Eye Institute (NEI), Neurobiology, Neurodegeneration and Repair Laboratory requires the upgrade of its Government-owned Illumina NextSeq 1000 sequencing system to NextSeq 2000 capability. The upgrade will provide expanded sequencing flexibility and capacity by enabling the use of additional flow cell configurations and higher-throughput sequencing applications. The contractor shall provide all labor, materials, parts, equipment, software, travel, installation, testing, and technical services necessary to complete the upgrade and deliver a fully functional NextSeq 2000 instrument configuration.

The existing sequencing platform is manufactured by Illumina and is currently integrated into established laboratory workflows, sequencing protocols, software environments, and consumables. The required upgrade is proprietary to Illumina and consists of the manufacturer-authorized NextSeq™ 1000 to NextSeq 2000 Upgrade, Part Number 20047256. Compatibility with existing Illumina sequencing kits, reagents, hardware architecture, software, and validated research workflows is essential to support ongoing scientific studies and maintain operational continuity.

Based on market research, HHS has determined that Illumina, Inc. is the only known source capable of providing the proprietary manufacturer-authorized upgrade required to convert the existing NextSeq 1000 system to NextSeq 2000 capability. No other vendor is authorized to provide this specific upgrade, associated proprietary components, software modifications, installation services, and system validation necessary to maintain full manufacturer-supported functionality. Therefore, Illumina, Inc. is the only source reasonably available to satisfy the Government’s requirement.

This notice is not a request for competitive quotations. However, any interested party that believes it can meet the Government’s requirement may submit a capability statement, proposal, or quotation for consideration. Responses must be submitted in writing and contain sufficient technical documentation to demonstrate the capability to provide the required upgrade and associated services.

Responses to this notice shall be submitted via email to the Contract Specialist Mesfin Alemayehu, at mesfin.alemayehu@hhs.gov no later than 2 p.m. EST Friday , June 26, 2026.

A determination by the Government not to compete this proposed requirement based upon responses to this notice is solely within the discretion of the Government. Information received will be considered for the purpose of determining whether to conduct a competitive procurement. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. To receive an award, contractors must be registered in SAM.gov and maintain an active registration.

***Please reference the attached Statement of Work for additional details regarding the required services and deliverables.***