This Pre-Solicitation opportunity from Department Of Health And Human Services was posted on June 18, 2020. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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NOTICE OF INTENT TO SOLE SOURCE - NEW MEDICATION DATA SURVEILLANCE PROJECT

Closed

2020-45633Federal

Submission Closed07/01/2020, 05:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 54171

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Federal

NATIONAL CANCER INSTITUTE (NCI) SMALL BUSINESS INNOVATION RESEARCH (SBIR) INNOVATIVE CONCEPT PHASE I AWARD PROGRAM

Solicitation # 75N98026R00109

The National Cancer Institute (NCI) is soliciting Phase I Small Business Innovation Research (SBIR) proposals under the Innovative Concept Award Program to advance research and development in therapeutic or preventative technologies, and devices, diagnostic tools, or digital health solutions for pediatric cancers and rare cancers, particularly those with a 5-year survival rate below 50%. This solicitation, numbered 75N98026R00109, is a total small business set-aside under FAR 19.5 with a NAICS code of 54171 and is open exclusively to small business concerns registered in the System for Award Management (SAM) and the SBA Company Registry, with a valid Unique Entity Identifier. Proposals must demonstrate scientific merit without requiring preliminary data, but must clearly articulate an unmet clinical need, the targeted cancer type, a viable development path, and a plan to generate initial proof-of-concept data through well-reasoned experiments. The base R&D budget is $300,000, with an optional additional $6,500 available for technical and business assistance, resulting in a potential contract value of up to $306,500. Amendments to the original solicitation have removed all requirements related to the Data Management and Sharing Plan in Sections 5.9, 6.1, and 8.5, while all other terms, conditions, and submission deadlines remain unchanged. The proposal deadline is September 21, 2026, at 5:00 p.m. Eastern Daylight Time, and submissions must be made electronically via the eCPS portal as a three-part package: a single PDF Technical Proposal including the required form and NIH biosketches, a completed Human Subjects and Clinical Trials Information Form (even if no human subjects are involved), and a single PDF Business Proposal with pricing details. Evaluation will assess technical acceptability, scientific rationale, and security risk as pass/fail gates, followed by a second review by NCI program staff. Contract administration requires electronic funds transfer for payment, mandatory SAM registration as a prerequisite for payment, and compliance with Section 508 for electronic reporting. Non-exempt human subjects research is prohibited, and all contractors must comply with human subjects protection regulations as outlined in 45 CFR part 46, maintain an active Federal-wide Assurance, and adhere to ethics, equal opportunity, E-Verify, and patent infringement reporting requirements. All awards are contingent on funding availability

POSTED

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Chain Reaction Innovations - Energy Technology Innovation

Solicitation # 6-BB47-P-00203-00

The Chain Reaction Innovations program, solicited under number 6-BB47-P-00203-00 and administered by Argonne National Laboratory on behalf of the U.S. Department of Energy, is designed to accelerate the commercialization of early-stage physical science innovations with potential impact on U.S. energy competitiveness. This opportunity is structured as a Cooperative Research and Development Agreement (CRADA), not a traditional procurement contract, and is open to individual U.S. citizens or lawful permanent residents who serve as the technical lead. Participants gain access to Argonne’s world-class facilities, mentorship, and an ORISE fellowship for up to 24 months, with funding contingent on DOE approval and successful performance reviews. The program consists of two phases: an initial six-month Scope and Planning Phase focused on market analysis and developing a DOE-approved Intellectual Property Management Plan, followed by an R&D Phase conducted on-site at Argonne in Lemont, Illinois. Crucially, applicants must secure a license or option to any background intellectual property essential to their project within one year, or face program termination. Eligibility is strictly defined: individuals with more than $2 million in private equity funding are excluded; current Argonne employees must terminate employment or take approved entrepreneurial leave; and any affiliation with Argonne, UChicago Argonne LLC, or the University of Chicago requires an Organizational Conflict of Interest management plan. Application materials must be non-proprietary and submitted exclusively through the online portal at chainreaction.anl.gov, including a one-page resume and a five-page technical deck. Proposals are evaluated holistically based on the technical strength and outcome orientation of the project leader, the potential economic impact and technical merit of the innovation, and its alignment with DOE’s mission space — with no formal cost or pricing data provided, as the program is an incubation initiative rather than a purchased service. The evaluation does not follow a Lowest Price Technically Acceptable model, instead favoring a trade-off approach that prioritizes innovation, feasibility, and strategic alignment. Access to program benefits is entirely contingent on CRADA execution, compliance with DOE directives on foreign national access, and continued performance through mandatory milestone reviews, particularly the year-one midpoint review.

Argonne National Labor - DOE Contractor

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Water Valve Leak Mitigation

Solicitation # FMP-NNL-0047

The Naval Nuclear Laboratory, operated by Fluor Marine Propulsion under contract with the Department of Energy, is seeking information on innovative methods to mitigate water leakage past valves during maintenance of pure water fluid systems. This request is purely for market research and not a solicitation for proposals or contracts. The goal is to identify non-intrusive solutions that prevent continuous water flow into work areas without compromising pure water chemistry or the integrity of stainless-steel components. Proposed methods must not require removal after use, must not introduce foreign materials into the system, and must either be applied externally, completely dissolve into innocuous constituents at room temperature, or otherwise avoid permanent modification of the system. The emphasis is on practical, reliable alternatives to freeze seals that reduce resource consumption during maintenance or welding operations. Responses are limited to five pages and must be submitted by September 3, 2026. This initiative is managed by Fluor Marine Propulsion, the DOE contractor overseeing the Naval Nuclear Laboratory, with inquiries directed to ATIP@unnpp.gov. The effort is classified under NAICS code 54171 and is intended to assess industry capabilities to support future procurement decisions. Interested parties should note that no costs incurred in preparing responses will be reimbursed, and submission of information does not guarantee future contract opportunities. All responses will be used solely for planning and market analysis purposes.

Fluor Marine Propulsion - DOE Contractor

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Solicitation # N0016425SC001

The Naval Surface Warfare Center, Crane Division is executing a Commercial Solutions Opening (CSO) under solicitation number N00164-25-S-C001 to rapidly identify and acquire innovative commercial technologies relevant to Expeditionary Warfare, Strategic Missions, and Electromagnetic Warfare. This open solicitation is authorized under 10 U.S.C. 3458 and leverages Other Transaction Authority (OTA) under 10 U.S.C. 4022 and 4023 to facilitate non-traditional partnerships and accelerate the integration of commercially developed, non-classified solutions into defense applications. The process is structured into three phases: Solution Brief submission, a pitch session, and a full proposal, with all awards being fixed-price and based on technical merit, relevance to the stated Areas of Interest (AOIs), feasibility, and rapid testability rather than cost competition. Submissions must be unclassified, electronically delivered in PDF format, and adhere to strict page limits—five pages for Solution Briefs or fifteen slides alternatively—with mandatory inclusion of entity information, executive summary, innovation justification, technical approach, IP considerations, and company background. The Government evaluates submissions independently per AOI, without comparison against other proposals, and invites only a select number to proceed to pitch and proposal stages. Multiple awards may be issued, and successful prototype projects may lead to non-competitive follow-on production contracts. The CSO has issued multiple AOIs targeting specific capability gaps, including the Miniature Aiming System for the .338 Norma Magnum LMG, the Lightweight Machine Gun replacement for the MK48 series, the Small Modular Optic and Laser Designator (SMOLDr), the HICAR system components, and modular electro-optic designator/optic modules. Each AOI has unique technical requirements, submission windows, and designated points of contact for questions and submissions, such as Bradly McLaughlin, Kaden Pfender, and Connor Fields. Deadlines vary by AOI, with some closing in 2025 and others extending into 2026, including Q&A and proposal submission windows ranging from August 2025 through June 2026. Proposals must demonstrate innovation as defined by novelty or new application of existing technology as of the submission date. Entities must be registered in SAM with a valid DUNS and CAGE code to receive awards and must not be suspended or debarred. For OTAs over $5 million, the Comptroller

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2026 Astrophysics Small Explorer (APSMEX)

Solicitation # NNH26ZDA011O

The 2026 Astrophysics Small Explorer (APSMEX) solicitation, identified by number NNH26ZDA011O, invites Principal Investigator-led space science missions aimed at advancing understanding of fundamental astrophysical phenomena such as black holes, dark energy, galaxy evolution, and exoplanet habitability. The announcement is open to U.S. and non-U.S. entities including educational institutions, industrial organizations, and nonprofit organizations, with a focus on integrated Phase A and B mission concept development through a single-step competitive selection. Proposals must be submitted electronically via NSPIRES by September 9, 2026, and compliance with all administrative, technical, and regulatory requirements outlined in the full Announcement of Opportunity is mandatory. A mandatory Notice of Intent was due on July 21, 2026, and stakeholders were encouraged to review the accompanying 9JuneEmail.pdf, which included critical earlier dates such as a virtual preproposal conference held on June 30, 2026. Proposers must register in SAM.gov and are required to adhere to specific China-related collaboration restrictions outlined in Sections 4.2.2 and 5.8.1 of the AO, with any questions directed exclusively via email to both primary and secondary points of contact using the subject line "APSMEX26". The NAICS code 54171 applies, reflecting research in astronomical and space sciences, and while no fixed contract value or pricing structure is specified, selected missions will be funded within NASA Science Mission Directorate budget constraints. There are no specified packaging, marking, or preservation requirements, and no formal inspection or acceptance procedures are detailed in the provided materials; performance location is not defined beyond administrative oversight by NASA Headquarters in Washington, DC. The solicitation does not include explicit evaluation criteria, cost ceiling limits, or contract type designations, and payment or invoicing methods such as WAWF or IPP are not addressed. UEI and CAGE codes are implicitly required due to federal registration mandates through SAM.gov, and while socioeconomic status is not directly evaluated, small businesses are eligible under the SBA size standard of $18 million annual receipts. All substantive contractual terms, representations, certifications, and technical specifications are contained exclusively within the official AO on NSPIRES, which supersedes any summary or external reference. Proposers are responsible for regularly monitoring NSPIRES for amendments and ensuring full alignment with the latest version of the solicitation, as this document serves as the

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Request for Information (RFI): Private Sector Partnerships in Astrobiology, Planetary Protection, and Space Biology

Solicitation # NNH26ZDA010L

NASA has issued a Request for Information (RFI) under solicitation number NNH26ZDA010L to gather informal input from the private sector on potential partnerships in astrobiology, planetary protection, and space biology. This notice, posted on May 18, 2026, and open for responses until August 11, 2026, is not a solicitation for contracts, grants, or agreements, and NASA makes no commitment to act on any submissions. Respondents are encouraged to submit partnership ideas in key areas such as technology development, data analytics and AI, life detection and sample analysis, applied astrobiology, space biology, and communications outreach. All responses must be submitted electronically through the NSPIRES portal, and interested parties are responsible for monitoring the system for any amendments. The RFI does not require formal proposals, certifications, or cost estimates, and no evaluation factors, contracting clauses, or award mechanisms are in place. The primary point of contact for inquiries is Rebecca McCauley Rench at NASA Headquarters in Washington, D.C., and while no specific submission format or length restrictions are defined, responses are expected to be concise and delivered via standard electronic means, typically PDF. The NAICS code 54171 applies, and no set-aside or socioeconomic preferences are in effect. This RFI is strictly an exploratory tool to inform future planning and does not constitute a procurement action.

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Research Opportunities for International Space Station (ISS) Utilization

Solicitation # 80JSC026ISSNRA

NASA Johnson Space Center is soliciting proposals under the open Research Opportunities for International Space Station (ISS) Utilization announcement, identified as 80JSC026ISSNRA, to advance exploration technology demonstration and enhance National Lab utilization on the ISS. Originally issued in November 2012, the notice remains open for submissions, with individual focus areas potentially having distinct deadlines. Proposals may be awarded through various mechanisms including commercial and non-commercial contracts, cooperative agreements, or grants, depending on the nature and scope of the project. The North American Industry Classification System code applicable is 54171, and performance is expected to occur in Houston, Texas. All responsible sources are eligible to submit offers, and there is no specific set-aside for small businesses or other categories. Applicants must register and monitor the NASA Solicitation and Proposal Integrated Review and Evaluation System (NSPIRES) for the solicitation, amendments, and submission requirements, as it is the sole source for official documents. The primary point of contact is Colleen Corbett, with secondary support from Samuel Mcilvoy, and the Center Ombudsman provision under NASA Clause 1852.215-84 is in effect for dispute resolution.

NASA Johnson Space Center

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Astrobiology Science Conference Announcement for Partnership Proposals 2026

Solicitation # NNH26ZDA009L

NASA is seeking a non-reimbursable partnership to collaboratively plan, organize, and execute the 2026 Astrobiology Science Conference (AbSciCon) through an Announcement for Partnership Proposals (AFPP) under solicitation number NNH26ZDA009L. The solicitation, issued by NASA Headquarters under the Science Mission Directorate’s Planetary Science Division, is open for submissions via the NASA Solicitation and Proposal Integrated Review and Evaluation System (NSPIRES) with a deadline of July 17, 2026. Interested parties must download the full AFPP document from NSPIRES, which includes a referenced summary PDF titled "AbSciCon_AFPP_NSPIRES_Summary_April_2026" and must monitor the portal for any amendments. The partnership will involve end-to-end logistics coordination, scientific program development, and engagement with the international astrobiology community, including agencies like NSF, NIH, and DOE, with no financial exchange anticipated. Performance is expected to center in Washington, D.C., and the sole point of contact for inquiries is Rebecca McCauley Rench at NASA Headquarters. The solicitation does not include pricing, contract line items, or reimbursement, as it is structured as a non-funding partnership, and no set-aside classifications apply. Proposers are responsible for ensuring compliance with NSPIRES submission guidelines, using the provided solicitation number to access all documents, and are advised that evaluation criteria, delivery specifications, inspection protocols, representations, certifications, and special requirements are not detailed in the public synopsis and must be obtained from the complete AFPP on NSPIRES.

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Defense Innovation Unit Commercial Solutions Opening

Solicitation # HQ0845-20-S-C001

The Defense Innovation Unit (DIU) has issued a streamlined Commercial Solutions Opening (CSO) to solicit proposals for innovative commercial technologies that can advance asymmetric defense capabilities and improve the effectiveness of military personnel and existing defense platforms, components, or materials. This competitive process targets both traditional and nontraditional defense contractors, encouraging participation from companies with new or novel applications of technology, processes, or business practices that can sustain global peace and bolster U.S. national security. The CSO uses Other Transaction Agreements (OTA) under authority 10 U.S.C. § 2371b to facilitate flexible engagement and rapid development of prototype projects, which may entail concept demonstrations, pilots, and agile improvements to government systems. The solicitation process is structured in three phases, beginning with the submission of Solution Briefs responding to broad Areas of Interest (AOIs) posted on the DIU website, followed by invitation-only pitch sessions and culminating in full proposal submissions for potential award. The AOIs are subject to periodic updates, and interested parties are encouraged to monitor the DIU website closely for opportunities and deadlines. While participation costs are generally not reimbursed, this streamlined approach is designed to lower barriers for commercial vendors and entities new to government contracting. The initiative aims to accelerate the integration of advanced commercial technologies into defense applications to enhance mission effectiveness and national security capabilities. DIU operates out of Mountain View, California, and provides a primary point of contact via email for inquiries and submissions.

Defense Innovation Unit

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Washington Headquarters Services (WHS) Commercial Solutions Opening (CSO)

Solicitation # HQ0034259WHSCSO

The Washington Headquarters Services Acquisition Directorate (WHS/AD) operates as the Single Enterprise Contracting Office (SECO) to the Office of the Secretary of War and mission partners within the Department of War, managing innovative acquisitions under authorities granted by 10 U.S.C. §§ 3458 and 4022. This Commercial Solutions Opening (CSO) serves as a special notice solicitation (HQ0034259WHSCSO) posted on March 26, 2026, with responses accepted through March 12, 2030. It is designed to solicit innovative commercial solutions, including commercially available technologies, concept demonstrations, pilots, and agile development activities capable of accelerating defense capability delivery. The CSO encourages participation from traditional and nontraditional defense contractors, including small businesses and non-profits, across a diverse range of Areas of Interest (AOIs) posted separately on the Government Point of Entry (https://sam.gov). Amendments to the CSO have updated various aspects such as description, contact points, and submission instructions, reflecting the evolving nature of this solicitation over its five-year open period. Unlike traditional FAR-based contracts, this CSO uses Other Transaction Authority (OTA), allowing for flexible, prototype-driven agreements outside the Federal Acquisition Regulation framework. The award process emphasizes holistic evaluation factors, primarily including the technical merit and feasibility of solutions relative to the posted AOIs, business viability of offerors, acceptability of cost estimates and schedules, and the impact of data rights assertions. Awards are made via a trade-off evaluation focused on potential impact rather than lowest-price criteria. Performance periods typically span up to 24 months per project and require deliverables that meet agreed-upon technical goals and success metrics, with completion and acceptance decisions made by the Government’s Agreements Officer. Proposals must adhere to strict submission formats outlined in the Request for Prototype Proposal (RPP), including an Affirmation of Business Status Certification (ABSC) to verify eligibility as small or nontraditional defense contractors or foreign-owned entities with additional compliance requirements. Special contract conditions include Comptroller General audit access for awards exceeding $5 million, procurement integrity requirements, and iterative prototyping authority permitting mutual modifications to project scope. Communications and submissions are conducted electronically in unclassified formats, and contractors are obligated to maintain active registrations in SAM with valid UEI and CAGE codes. The contract administration relies on the WHS/AD Agreements Officer exclusively for contract execution, oversight, and acceptance decisions, and invoicing is processed through the Wide Area Work Flow (WAWF) system. No packaging, marking,

Washington Headquarters Services

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Request for Information (RFI) for Advancing Critical and Emerging Microelectronics Technologies

Solicitation # 26_04

This request for information seeks input to advance the United States' leadership and domestic capabilities in critical and emerging microelectronics technologies, with a focus on strengthening the semiconductor supply chain and promoting innovative research and development. Sandia National Laboratories, as a key U.S. research institution, is soliciting proposals that address several priority areas including advanced semiconductor devices and materials, microelectronics fabrication and characterization, AI applications specifically tailored to microelectronics R&D, quantum technology development, and commercialization of federally funded technological innovations. The initiative emphasizes a broad range of advanced technologies such as neuromorphic computing, power electronics using emerging materials, quantum sensors, heterogeneous integration techniques, AI-driven manufacturing automation, and secure supply chain metrology. Proposals should demonstrate technical expertise and relevance to these domains, with a clear understanding of the goals to enhance U.S. innovation and national security through domestic manufacturing improvements and cutting-edge technology development. Responses must not exceed five pages, submitted by October 1, 2029, and will be evaluated based on completeness, clarity, relevance, and respondent qualifications. Contact points are provided for inquiries, and additional supporting materials such as case studies are encouraged to showcase experience and capabilities in advancing critical microelectronics technologies.

POSTED

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LPS Qubit Collaboratory (LQC)

Solicitation # W911NF21S0009

The LPS Qubit Collaboratory (LQC) initiative, led by the U.S. Army Research Office in partnership with the NSA’s Laboratory for Physical Science, seeks to advance fundamental research in quantum information science and technology, with a strong emphasis on qubit development for quantum computing and sensing applications. The program aims to foster disruptive technologies, build deep collaborative partnerships across academia, industry, Federally Funded Research and Development Centers (FFRDCs), and government laboratories, and develop the next generation quantum workforce through research experiences and fellowships. Proposals are solicited under three categories: Incubator proposals for small research groups or single investigators to explore new concepts; Collaboratory proposals that focus on long-term, team-based projects addressing core quantum challenges; and Quantum Computing Research (QuaCR) fellowships supporting U.S. graduate students and postdoctoral researchers in relevant fields. The broad agency announcement also highlights the importance of solving key obstacles in quantum information science, such as device design limits, materials for qubit fidelity, novel qubit physics, and integration of classical and quantum components. A special focus is placed on research involving superconductor qubits and accelerating understanding in quantum computing fundamentals. Proposals will be evaluated for potential awards through grants, cooperative agreements, or contracts. The program encourages collaboration without regard to physical location by leveraging shared resources and data. The deadline for proposal submission is April 30, 2027, and points of contact are designated for inquiry and submission coordination. This effort underpins critical DoD interest in progressing quantum technologies and cultivating a skilled workforce to sustain long-term advancements.

W6QK Acc-Apg Durham

POSTED

4 months ago

DEADLINE

in 9 months

General Info

Agency

Department Of Health And Human Services → CDC Office Of Financial ResourcesView Agency

NAICS

54171View NAICS

Place of Performance

GA, USA

Set-Aside

NONE

Documents

(1)

Request+for+Quotes.doc

DOC

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Timeline

1 update

PhaseClosed

PostedJun 12

Presolicitation

Amendment 1Jun 18

Contract was updated

Response DeadlineJul 1

Deadline has passed

Submission Closed

07/01/2020, 05:00:00 PM UTC

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Organization & Contact Information

AgencyDepartment Of Health And Human Services → CDC Office Of Financial Resources

Contacts2 people available

OfficeAtlanta, GA, 30329, USA

Organization / Agency

Department Of Health And Human Services → CDC Office Of Financial Resources

View Agency Profile

Office AddressAtlanta, GA, 30329, USA

Contacts

Violet Crawford

Jerry Outley

Full Description

NOTICE OF INTENT TO SOLE SOURCE The Centers for Disease Control and Prevention (CDC) intends to award a sole-source firm-fixed price purchase order to The Institute for Biometry and Edpidemiology German Diabetes Center for the estimation and modeling of trends in hypertention incidence in U.S. adults with and without diabetes. This requirement is for (supplies/services) in which the Government intends to solicit and negotiate with only one-source under the authority of FAR 13.106-1(b) (SAP) and 41 U.S.C. 3304(a)(1). Interested persons may identify their interest and capability to respond to the requirement. This notice of intent is not a request for competitive quotations; however, all responses received within seven (7) days of the issuance of this notice will be reviewed. A determination by the government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the government. Information received will be considered solely for the purpose of determining whether to conduct a competitive procurement. Any response should be emailed to the contract specialist at ycf1@cdc.gov by 1:00 p.m. Eastern Standard Time (EST) on July 1, 2020 @ 1:00 p.m.