OD2A-S Overdose Prevention and Response Expansion

The OD2A-S Overdose Prevention and Response Expansion solicitation, identified as 2026-RFA-204, is issued by the Mississippi Pharmacy agency with a response deadline of August 21, 2026. This initiative is based on the CDC's Overdose Data to Action in States (OD2A-S) framework, which provides funding to state health departments to enhance surveillance and prevention efforts regarding opioids, stimulants, and polysubstance use. The program emphasizes a data-driven approach to combat the overdose crisis, focusing on health equity and the integration of morbidity and mortality surveillance to inform public health responses. Key operational requirements include the implementation of the State Unintentional Drug Overdose Reporting System (SUDORS) and the use of the DOSE system for reporting nonfatal overdoses. The contract outlines rigorous data sharing, quality control, and dissemination mandates, including specific metadata and indicators for data linkage strategies. Funding is allocated based on drug overdose death rates and counts, supporting activities such as comprehensive toxicological testing, Targeted Evaluation Projects to assess care navigation, and the staffing of abstractors for case reporting. Recipients must adhere to strict CDC reporting timelines and utilize culturally responsive frameworks to evaluate and improve harm reduction and care linkage services.