Pancreatic Cancer Detection Consortium: Management and Data Coordination Unit (U24 Clinical Trial Not Allowed)

The National Cancer Institute is soliciting applications under PAR-28-057 to establish the Management and Data Coordination Unit (MDCU), a critical scientific component of the Pancreatic Cancer Detection Consortium (PCDC). The MDCU is tasked with advancing the early detection of pancreatic ductal adenocarcinoma and the characterization of precursor lesions by providing essential organizational, logistical, and technical support. Key responsibilities include managing study design, protocol development, statistical analysis, and data management for approved studies. Additionally, the unit will coordinate biorepository building for prospective cohorts, manage the transfer of biospecimens to the NCI at Frederick Central Repository, maintain the PCDC portal and Manual of Operations, and implement secure data storage and analysis infrastructure. This is a five-year cooperative agreement with an estimated total cost of 825,000 dollars per year, with direct costs capped at 500,000 dollars annually. Applications are open to a wide range of eligible organizations, including higher education institutions, nonprofits, for-profit organizations, and government entities. Awards are based on scientific and technical merit as determined by the NIH peer review system, focusing on significance, investigator expertise—specifically strong statistical experience—and innovation in management strategies. Applicants must maintain active registrations in SAM, eRA Commons, and Grants.gov. Submission deadlines are set for January 25, 2027, and May 25, 2027. Recipients must also adhere to strict cybersecurity guidelines, including a requirement to notify HHS of any security incidents within 48 hours of discovery.