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Pilot and Feasibility Studies in Preparation for Substance Use and HIV Prevention Intervention and Services Research Trials (R34 Clinical Trial Optional)

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PAR-28-093Grant

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The National Institute on Drug Abuse, under the National Institutes of Health, is soliciting applications for pilot and feasibility studies through solicitation PAR-28-093. This funding opportunity is designed to support preliminary research that informs the design and execution of future efficacy, effectiveness, and services research trials. Eligible projects may focus on developing interventions to prevent substance use and disorder, researching prevention and recovery services for comorbid pain and mental health disorders, or conducting HIV eradication research within substance use populations, including implementation science. The solicitation was posted on October 19, 2026, with a response deadline of July 17, 2029. This federal opportunity specifically targets the preparation phase of clinical trials to ensure that subsequent large-scale research is well-informed and feasible. Interested parties can find further details and application instructions via the official grants portal.

General Info

NIDA solicits pilot study applications for substance use and disorder research by July 2029.

Agency

National Institutes Of Health → National Institute On Drug Abuse

NAICS

541720 - Research and Development in the Social Sciences and Humanities

Place of Performance

Not specified

Set-Aside

NONE

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Organization & Contact Information

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AgencyNational Institutes Of Health → National Institute On Drug Abuse
ContactsNo contacts available
OfficeUSA
Organization / AgencyNational Institutes Of Health → National Institute On Drug Abuse
Office AddressUSA
ContactsNo contact information available

Full Description

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The purpose of this notice of funding opportunity (NOFO) is to support pilot and feasibility studies to inform the design and conduct of efficacy, effectiveness, and/or services research trials. Topics may include: 1) developing interventions to prevent substance use, misuse, or progression to substance use disorder; 2) prevention, treatment, or recovery services research, including research addressing comorbid pain and medical and mental health disorders; and 3) HIV eradication research, including implementation science, prevention, treatment and recovery in substance use settings/populations.

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