This Pre-Solicitation opportunity from Department Of Health And Human Services was posted on February 16, 2022. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

Top

Proteomic Analysis of Radiation Induced Biomarkers in Murine Plasma

Closed

75N91022Q00031Federal

Submission Closed02/23/2022, 05:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

Active Opportunities Like This One

NAICS: 541380

New

Testing ServicesThis subcontract opportunity with PM Construction & Rehab, LLC involves providing quality assurance and compliance testing for municipal sewer rehabilitation projects located in Shawnee, Oklahoma. The selected contractor will be responsible for performing critical technical evaluations, including pressure testing, leak detection, and soil compaction testing, to ensure all work meets project specifications. The primary deliverable for these services is the provision of certified test reports. The contract is specifically set aside for small businesses, including SBA certified Women-Owned Small Businesses and SAM.gov designated Small Disadvantaged Businesses, falling under NAICS code 541380. Interested parties must note the tight response window, with the solicitation posted on October 30, 2026, and a response deadline of November 2, 2026.

PM Construction & Rehab, LLC

POSTED

DEADLINE

Fire Flow Testing Services

Solicitation # 121589

The Washington Suburban Sanitary Commission (WSSC) is soliciting sealed responses for solicitation number 121589 to establish a Fire Flow Testing Services program. The contractor will be responsible for the planning, locating, inspection, and testing of fire hydrants and associated water distribution components across various pressure zones in Maryland to evaluate hydraulic performance. Key technical tasks include measuring static pressure, residual pressure, and flow rates, as well as performing traffic setup and maintenance for residential, county, and state roads. The project involves a base quantity of 1,500 fire flow tests, 3,000 hydrant inspections, and 3,000 valve inspections, with pricing options for three additional years. To be considered, bidders must possess at least five years of experience as a prime contractor and provide at least two crews, each led by a professional with three years of expertise. Crucially, at least one crew member must hold a current Maryland Water Distribution System Operator D-1 license. Bidders must also provide a comprehensive equipment list and adhere to AWWA and MDE standards, including specific requirements for chlorinated water discharge. The contract will be awarded to the lowest responsive and responsible bidder who meets all minimum qualifications. Submissions are due by November 30, 2026, via the WSSC eProcurement Portal. Contract administration includes strict quality assurance requirements, requiring the implementation of a QA/QC plan and immediate reporting of residual pressures falling below 20 psi. Contractors must maintain significant insurance coverages, including Commercial General Liability, Pollution Liability, and Errors and Omissions, each with limits up to 2,000,000 dollars. Payment is processed via ACH or procurement credit card within 30 days of acceptance. Additionally, the contract incorporates a Mid-Atlantic Purchasing Team clause, allowing other public entities to utilize the resultant contract terms and pricing.

Utility Services Department

POSTED

DEADLINE

Product Verification Testing and Source Inspection for Critical LightingThis subcontract involves providing product verification testing and source inspection services for critical lighting items under the DLA Weapons Support Nuclear Reactor Program. The selected contractor will be responsible for conducting inspections and tests using sampling methods per MIL-STD-1916 or ASQ H1331, while ensuring that identification markings comply with MIL-STD-130N. Specialized equipment capable of verifying MIL-DTL-16377/8C and MIL-DTL-16377K SUP 1 is required to complete these tasks, with the final deliverables consisting of detailed inspection reports and test results. The project is categorized under NAICS code 541380 and will be performed in New Cumberland, Pennsylvania. Interested parties must respond by November 9, 2026, to support the Department of Defense in maintaining the quality and compliance of critical components for nuclear reactor program projects.

DLA WEAPONS SUPPORT NUCLEAR REACTOR PROGRAM

POSTED

DEADLINE

First Article Test (FAT) ServicesThis subcontract for First Article Test services supports prime contractors on DLA Weapons Support ASC projects to validate the manufacturing of pins. The scope of work involves verifying the material composition, performance, and dimensional accuracy of sample units using precision measurement tools and testing facilities in strict accordance with DLA FAT standards. The final deliverables for this engagement include the tested sample unit and a certified First Article Test report. The project is managed under the Department of Defense through the DLA Weapons Support ASC Commodities Division and is categorized under NAICS code 541380. Performance of these services will take place in Corpus Christi, Texas. Interested parties should note the response deadline of November 6, 2026.

DLA WEAPONS SUPPORT ASC COMMODITIES DIVISION

POSTED

DEADLINE

First Article Testing and Validation ServicesThis subcontract, titled First Article Testing and Validation Services, is a total small business set-aside issued by the Department of Defense under the DLA Weapons Support ASC Commodities Division. The project involves performing First Article Testing for prime contractors to ensure that initial production units meet strict close tolerance requirements and Navy-mandated safety specifications. Work is performed in San Diego and utilizes CMM and precision gauges to validate components before they are delivered for government approval. The selected contractor is responsible for providing comprehensive documentation and test results, culminating in the delivery of a First Article Test Report and an approved test unit. This effort falls under NAICS code 541380 and is critical for validating the quality and safety of supply contracts managed by DLA Weapons Support.

DLA WEAPONS SUPPORT ASC COMMODITIES DIVISION

POSTED

DEADLINE

Aerospace Quality Compliance & Certification ServicesThe Aerospace Quality Compliance and Certification Services subcontract involves providing technical verification and quality documentation audits for prime contractors supporting DLA Weapons Support ASC projects. The primary scope of work includes validating technical data against the DLA Master List of Technical and Quality Requirements and verifying Critical Application Item certifications specifically for ITT Aerospace part number 57802M. The selected provider must possess specialized expertise in AS9100 standards and DLA R and I quality codes to deliver comprehensive quality certification reports and compliance documentation packages. This Department of Defense requirement is managed by the DLA Weapons Support ASC Supplier Oper AE and AF Div, with the place of performance located in Tracy, California. The project falls under NAICS code 541380. Interested parties should note the response deadline of November 6, 2026, for this specialized aerospace quality assurance engagement.

DLA WEAPONS SUPPORT ASC SUPPLIER OPER AE AND AF DIV

POSTED

DEADLINE

First Article and Production Lot Testing ServicesThis subcontract opportunity with the Department of Defense, specifically the DLA Weapons Support ASC Commodities Division, requires an independent laboratory to perform critical testing and certification for prime contractors. The scope of work involves conducting First Article Testing and Production Lot Testing utilizing specialized equipment for material analysis, metrology, and hardness or stress testing. The selected provider will be responsible for delivering certified test reports and completing essential documentation, including DD Form 1222 and DD Form 250. The project is categorized under NAICS code 541380 and will be performed in Jacksonville, Florida. While not mandatory, ISO/IEC 17025 certification is preferred for this engagement. Interested parties must submit their responses by November 6, 2026, to support the quality assurance and certification requirements of DLA Weapons Support ASC projects.

DLA WEAPONS SUPPORT ASC COMMODITIES DIVISION

POSTED

DEADLINE

First Article Test (FAT) Validation and CertificationThis subcontract opportunity, issued by the Department of Defense for the DLA Weapons Support Aviation Supply Chain, involves performing First Article Testing (FAT) for internally relieved body bolts. The selected contractor will be responsible for validating the dimensions, material properties, and overall performance of a single sample unit against the technical data package. This process requires the use of Coordinate Measuring Machine (CMM) and material testing laboratory equipment to ensure full compliance. To qualify for Navy CSI validation, the contractor must hold AS9100 or ISO 9001 certification. The final deliverables for this project include a comprehensive FAT report and the return of the tested sample unit. This is a total small business set-aside under NAICS code 541380, with the place of performance located in Cherry Point. Responses are due by November 6, 2026.

DLA WEAPONS SUPPORT AVIATION SUPPLY CHAIN

POSTED

DEADLINE

First Article Testing and Inspection ServicesThis subcontract for First Article Testing and Inspection Services involves performing specialized testing and validation for prime contractors on DLA Troop Support aerospace projects. The scope of work requires the testing of three shoulder bolt units using metrology equipment to validate material properties and dimensions according to BAC drawings. The selected provider must apply sampling standards per MIL-STD-1916 or ASQ H1331, coordinate closely with the Quality Assurance Representative, and deliver a formal First Article Test Report. The project is managed by the Department of Defense under the DLA Weapons Support ASC Commodities Division and will be performed at Tinker AFB. To be eligible for this contract, the provider must hold AS9100 certification. The solicitation was posted on October 29, 2026, with a response deadline of November 6, 2026, falling under NAICS code 541380.

DLA WEAPONS SUPPORT ASC COMMODITIES DIVISION

POSTED

DEADLINE

Aerospace Quality Inspection and SamplingThis subcontract opportunity, titled Aerospace Quality Inspection and Sampling, is issued by the Department of Defense under the DLA Weapons Support ASC Supplier Oper AE and AF Div. The project involves performing quality verification and sampling for prime contractors on aerospace projects, specifically executing sampling plans according to MIL-STD-1916 or ASQ H1331. The scope of work requires verifying critical, major, and minor attributes with AQLs of 0.1, 1.0, and 4.0, utilizing certified Measuring and Test Equipment for dimensional inspections and providing final inspection reports and certifications of conformance. The contract is designated as a Total Small Business Set-Aside under NAICS code 541380, with the place of performance located in New Cumberland, Pennsylvania. Interested parties should note the response deadline of November 6, 2026.

DLA WEAPONS SUPPORT ASC SUPPLIER OPER AE AND AF DIV

POSTED

DEADLINE

First Article Testing (FAT) and Production Lot Testing (PLT)This subcontract, managed by the Department of Defense under the DLA Weapons Support Land Supply Chain, involves providing technical validation and testing services for prime contractors on US Navy aerospace projects. The scope of work focuses on conducting First Article Tests and Production Lot Tests using specialized rigs to ensure the structural and functional integrity of launch bar drive links. Because these components are classified as Navy Critical Safety Items, the contractor is responsible for delivering formal test reports and certifications of compliance. The project is categorized under NAICS code 541380 and will be performed in New Cumberland. Interested parties must adhere to the timeline established by the posting date of October 29, 2026, with a response deadline set for November 9, 2026. The primary deliverables for this engagement are the FAT Certification and the corresponding PLT Test Reports.

DLA WEAPONS SUPPORT LAND SUPPLY CHAIN

POSTED

DEADLINE

First Article Testing and Quality CertificationThis subcontract for First Article Testing and Quality Certification supports prime contractors on DLA Weapons Support ASC projects. The selected provider will perform inspections and certifications, specifically conducting First Article Testing according to PGN-09-01, preparing DD1222 forms for ESA submissions, and ensuring strict compliance with MIL-STD-129 and MIL-STD-2073-1E. Technical execution requires the use of precision gauges and Coordinate Measuring Machines to deliver certified inspection reports and First Article Test Reports. To qualify for this engagement, contractors must hold SAE AS9100 certification and maintain CMMC Level 2 compliance. The project falls under NAICS code 541380 and is managed by the Department of Defense under the DLA Weapons Support ASC Supplier Oper AE and AF Div. Responses are due by November 13, 2026, for performance located in the 17070-5002 zip code area.

DLA WEAPONS SUPPORT ASC SUPPLIER OPER AE AND AF DIV

POSTED

about 17 hours ago

DEADLINE

in 14 days

General Info

Agency

Department Of Health And Human Services → NIH Nci

NAICS

541380 - Testing Laboratories and Services

Place of Performance

MD, USA

Set-Aside

NONE

Documents

Notice+of+Intent+to+Sole+Source+-+SomaLogic+Final.doc

AI Contract Breakdown

Uniform Contract Format

Contract not broken down yet

CLEATUS splits the solicitation into Uniform Contract Format (UCF) sections: scope, pricing, deliverables, and evaluation criteria.

Timeline

PhaseClosed

PostedFeb 16

Presolicitation

Response DeadlineFeb 23

Deadline has passed

Submission Closed

02/23/2022, 05:00:00 PM UTC

Find active opportunities like this

Get full access to discover similar active contracts, track opportunities, and build proposals with AI assistance.

Organization & Contact Information

AgencyDepartment Of Health And Human Services → NIH Nci

Contacts1 person available

OfficeBethesda, MD, 20892, USA

Organization / AgencyDepartment Of Health And Human Services → NIH Nci

Office AddressBethesda, MD, 20892, USA

Contacts

David Romley

contact@example.gov

+1 (555) 000-0000

Full Description

General Information Short Title: Proteomic Analysis of Radiation Induced Biomarkers in Murine Plasma Document Type: Notice of Intent Solicitation Number: 75N91022Q00031 Posted Date: 2/16/2022 Response Date: 2/23/2022 Classification Code: B599 - Special Studies/ Analysis NAICS Code: 541380 - Testing Laboratories Contracting Office Address Department of Health and Human Services, National Institutes of Health, National Cancer Institute, Office of Acquisitions, 9609 Medical Center Drive, Room 1E232 Bethesda, MD 20892, UNITED STATES Description The U.S. Department of Health and Human Services (DHHS), National Institutes of Health (NIH), National Cancer Institute (NCI), Center for Cancer Research (CCR), Radiation Oncology Branch (ROB), intends to procure services on a sole source basis from SomaLogic, Inc. This procurement is being conducted using commercial item procedures pursuant to FAR Part 12 and FAR Part 13, specifically FAR Subpart13.106-1(b)(1)(i) allowing the Contracting Officer (CO) to solicit from one source. Only one award will be made as a result of this solicitation. This will be awarded as a Non-Severable) firm fixed price type contract. It has been determined there are no opportunities to acquire green products or services for this procurement. BACKGROUND The National Cancer Institute (NCI), Center for Cancer Research (CCR), Radiation Oncology Branch (ROB) has characterized novel radiation responsive proteins and correlated their patterns of expression with absorbed dose in models of both total body and partial body exposure. CCR's most recent work using the Somalogic SOMAscan 1.3K Analyte Assay which uses a proprietary aptamer-based approach to simultaneously screen 1,310 analytes, yielded novel panels of significantly altered proteomic biomarkers of radiation exposure. CCR's collective studies have consistently shown that higher predictive accuracies for radiation exposure and level of dose prediction are achieved when multiple biomarkers are used and the benefit of taking advantage of highly multiplexed proteomic expression analysis technologies. The primary objective of this project is to expand on our previous studies by using the latest Somalogic SOMAscan 7K Assay with both female and male C57BL6 TBI murine models. The NCI will characterize dose predictive proteomic signatures using both female and male C57BL6 mice and construct dose predictive algorithms which will then be tested in a multi-strain comparison of female TBI mice including CD2F1, BALB/c, C3H/HeJ and CD1 murine strains. OBJECTIVE The objective of this acquisition is to procure Proteomic Analytic services for 214 murine plasma samples. SCOPE The scope of the work to be performed is limited to a single screening of proteomic biomarkers in murine plasma samples submitted to SomaLogic for application on the SOMAscan Assay platform. The work will include sample processing, running of the assay to analyze over 7000 proteins and final data analysis. The SOMAscan 7K assay measures 7000 protein analytes in only 130 - L of serum, plasma or cerebrospinal fluid, or equally small amounts of a variety of other biological matrices. The assay shall quantify proteins that span over 8 logs in abundance (from femtomolar to micromolar), with reproducibility of 4.6 median %CV. The SOMAscan proteomic assay is enabled by a new generation of protein-capture SOMAmer (Slow Off-rate Modified Aptamer) reagents. SOMAmer reagents are constructed with chemically modified nucleotides that greatly expand the physicochemical diversity of the large randomized nucleic acid libraries from which the SOMAmer reagents are selected. The SOMAscan Assay measures native proteins in complex matrices by transforming each individual protein concentration into a corresponding SOMAmer reagent concentration which is then quantified by standard DNA techniques such as microarrays or qPCR. Data analysis will include internal standardization and normalization and preparation of the final report. CONTRACT REQUIREMENTS/ AND PERSONNEL QUALIFICATIONS TASK 1: PROCESS EACH SAMPLE Upon receipt of samples from the Government, the Contractor shall verify each sample label and the overall inventory of samples. The Contractor shall also aliquot from primary samples and any necessary dilutions for application on the assay platform. TASK 2: RUN ASSAY ANALYSIS The Contractor's assay analysis shall include 7000 protein analytes conducted on samples of at least 130 - L. The analysis shall quantify proteins that span no less than 8 logs in abundance (from femtomolar to micromolar), with reproducibility of 4.6 median % CV. The Contractor's assay shall measure native proteins in complex matrices by transforming each individual protein concentration into a corresponding reagent concentration, which is then quantified by standard DNA techniques such as microarrays or qPCR. TASK 3: DELIVER FINAL DATA AND ANALYSIS REPORT The Contractor shall deliver a report which includes analysis data normalized against intra assay controls and secondary normalization to interpolate control standards. Data will be supplied for all submitted samples in the form of Relative fluorescent units (RFU) for all aptamers present in the assay. GOVERNMENT RESPONSIBILITIES The Government technical point of contact (TPOC) will coordinate with the Contractor to deliver samples to the Contractor's facilities. Samples shall be shipped no later than 45 calendar days after award. The Government will be responsible for arranging shipment of samples to and from the Contractor. TYPE OF ORDER This shall be issued as a Non-Severable Firm Fixed Price Purchase Order. NON-SEVERABLE SERVICES The services procured in this order are considered non-severable services. Funds are only available for use for the contract line item (CLIN) to which they are obligated. Unused funds from one CLIN may not rollover for use in other CLINs or order periods. PERIOD OF PERFORMANCE The period of performance is from April 1, 2022 to July 31, 2022.