Rabbit monoclonal antibodies (RabMab) using hybridoma technology

This is a brand name or equal solicitation in accordance with FAR 52. 211-6. This is a combined synopsis/solicitation Request for Quote for commercial items prepared in accordance with the format of FAR Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; quotations are being requested, and a written solicitation will not be issued. The solicitation number NIAID-RFQ-15-1749717 is issued as a Request for Quotation (RFQ). The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular FAC 2005-83, dated August 3, 2015. This acquisition will be processed under Simplified Acquisition Procedures (SAP) and is not a small business set-aside. The associated North American Industry Classification System (NAICS) Code is 325414, which has a size standard of 500 employees. The National Institutes of Health, National Institute of Allergy and Infectious Diseases in support of Vaccine Research Center (NIH/NIAID/VRC) has a brand name requirement for rabbit monoclonal antibodies (RabMab) using hybridoma technology from the only known source: Abcam Inc., 1 Kendall Sq., Ste B2304 Cambridge, MA 02139-1500. This vendor is known for its proprietary technology to produce rabbit monoclonal using hybridomas which our lab would like to produce rabbit monoclonal antibodies to a peptide antigen. This would provide us with a cell line to produce and purify the antibody. The lab currently uses rabbit polyclonal sera from a collaborator, which is greatly limited in supply. Changing reagents at this time would compromise on-going experiments and prevent proper interpretation of the results. NIH/NIAID/VRC would like to purchase the following: Item/Description/Quantity: 1. Peptide synthesis, catalog# AP006 (Qty-16) 2. Peptide Conjugation, for screening, catalog# AP005 (Qty-1) 3. Peptide conjugation, for immunization, catalog# AP009 (Qty-1) 4. Immunization (AAALAC/OLAW-assured facility, catalog# IM001L (Qty-2) 5. Production bleed collection, catalog# IM007 (Qty-8) 6. Antisera affinity purification, catalog# IM016 (Qty-1) 7. Splenectomy (OLAW-assured facility), catalog# FU001C (Qty-1) 8. Lymphocyte isolation from spleen, catalog# FU003 (Qty-1) 9. Fusion and multiclone standard ELISA screening, catalog# FU111 (Qty-1) 10. Subcloning and standard ELISA screening, catalog# SU001 (Qty-1) 11. Subclone delivery (frozen), catalog# SU016 (Qty-1) The government will award a firm fixed price purchase order for the purchase and delivery of brand name or equal, FAR 52.211-6 to the responsible contractor. The FOB point shall be Origin. The following Federal Acquisition Regulations provisions and clauses apply to the acquisition: FAR 52.204-7, System for Award Management (Jul 2013)-Potential Offerors must be registered prior to award, during performance, and through final payment of any contract, basic agreement, basic ordering agreement, or blanket purchasing agreement resulting from this solicitation; FAR 52.211-6 Brand Name or Equal (Aug 1999); FAR 52.212-1 Instructions to Offerors Commercial Items; FAR 52.212-2 Evaluation - Commercial Items; Quotes will be evaluated using Lowest Price Technically Acceptable criteria and past performance; Far 52.212-3 Offeror Representation and Certifications Commercial Items; Far 52.212-4 Contract Terms and Conditions Commercial Items; Far 52.212-5 Contract Terms and Conditions Required to Implement Statutes or Executive Orders Commercial Items; 52.204-10, Reporting Executive compensation and First-Tier Subcontract Awards (Jul 2013); 52.219-28, Post Award Small Business Program Representation (Jul 2013) (15 U.S.C. 632(a)(2)); 52.222-3, Convict Labor (June 2003); 52.222-19, Child Labor-Cooperation with Authorities and Remedies (Jan 2014); 52.222-21, Prohibition of Segregated Facilities (Apr 2015); 52.222-26, Equal Opportunity (Apr 2015); 52.222-36, Equal Opportunity for Workers with Disabilities (Jul 2014); 52.222-50, Combating Trafficking in Persons (Mar 2015); 52.223-18, Encouraging Contractor Policies to Ban Text Messaging while Driving (Aug 2011); 52.225-1, Buy American--Supplies (May 2014); 52.225-13, Restrictions on Certain Foreign Purchases (Jun 2008); FAR 52.232-33, Payment by Electronic Funds Transfer-System for Award Management (Jul 213), 52.242-13 Bankruptcy, 52.252-1 Provisions the full text of a solicitation provisions may be accessed electronically at this/these address(es): (http://farsite.hill.af.mil/vffara.htm), 52.252-2 Clause the full text of a solicitation provisions may be accessed electronically at this/these address(es): (http://farsite.hill.af.mil/vffara.htm), 52-253-1 Computer generated Forms, 52.203-3 Gratuities, 52.203-12 Limitation on Payments to influence Certain Federal Transactions, 52.203-17 Contractor Employee Whistleblower Rights and Requirements to Inform Employees of Whistleblower Rights. All responsible sources may submit offers that will be considered by this agency. All offers shall be submitted no later than 4:00 p.m. (ET) August 25, 2015 via electronic submission - email to Sylvia Robinson at srobinson@niaid.nih.gov . The email subject line must begin with and include solicitation# NIAID-RFQ-15-1749717. Fax submissions are not acceptable. Provide information required by FAR 52.211-6 when submitting offers for brand name or equal products. .