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Rapid Comprehensive Diagnostic Test for Multi-System Autoimmune Disease

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ARPA-H 06SBIR / STTR

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

AI Contract Overview

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Solicitation ARPA-H 06, issued by the Department of Health and Human Services, seeks the development of novel and rapid diagnostic assays for multi-system autoimmune diseases. The goal is to create a transformative tool that enables primary care physicians to diagnose and predict tissue-specific autoimmune manifestations, thereby streamlining specialist referrals. This effort leverages recent technological advances in detecting tissue-specific signatures of immune-mediated stress via circulating cells or molecular products. This is a Total Small Business Set-Aside under NAICS code 325413, structured as a Phase I SBIR/STTR project with options for Direct-to-Phase II or Fast-Track pathways. The procurement process requires a comprehensive submission including a four-page solution summary, a key personnel worksheet, a detailed cost proposal, and a GANTT chart with Go/No-Go indicators. Selected offerors must deliver a 16-slide technical presentation evaluated on technical merit, novelty, team expertise, and path to impact, specifically addressing the ARPA-H Heilmeier Questions. Awarded contractors must comply with Revised 508 Accessibility Standards for all ICT deliverables and utilize the Department of Treasury Invoice Processing Platform for electronic payments. Funding includes potential Technical and Business Assistance (TABA) requests of up to 6,500 dollars for Phase I and 50,000 dollars for Phase II.

General Info

ARPA-H seeks small businesses to develop rapid diagnostic assays for multi-system autoimmune diseases.

Agency

Department of Health and Human Services → Arpa-H

NAICS

325413 - In-Vitro Diagnostic Substance Manufacturing

Place of Performance

Not specified

Set-Aside

SBA

Documents

6

A06B Attachment A Contract Clauses

PDF, High priority: read this first13 pages · contract-clauses
High

A06B Attachment B Cost Proposal Spreadsheet Template

XLSX, High priority: read this first67 pages · cost-proposal
High

A06B Attachment C Key Personnel Worksheet Template

DOCX, High priority: read this first1 page · key-personnel-worksheet
High

A06B Attachment E SBP Oral Technical Presentation Template

PPTX, High priority: read this first11 pages · presentation-template
High

ARPA-H Gantt Chart Template

XLSX, High priority: read this first3 pages · sow
High

ARPA-H Small Business Program Solution Summary Submission Template

DOCX, High priority: read this first2 pages · sow
High

AI Contract Breakdown

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Timeline

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PhaseSolicitation
Posted

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Notice updated

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Response Deadline

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Organization & Contact Information

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AgencyDepartment of Health and Human Services → Arpa-H
ContactsNo contacts available
OfficeUSA
Organization / AgencyDepartment of Health and Human Services → Arpa-H
Office AddressUSA
ContactsNo contact information available

Full Description

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The purpose of this topic is to spur the development of novel, rapid diagnostic assays for multi-system autoimmune disease, which represents an unmet healthcare need. Moreover, in its ideal embodiment this diagnostic test might allow typical primary care physicians to diagnose and predict tissue-specific autoimmune disease manifestations, thereby streamlining referral of the patient to a specialist. This goal is made more feasible by recent technological developments including the ability to detect tissue-specific signatures of immune-mediated stress by assessing circulating cells and/or tissue-specific molecular products.

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