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This Sources Sought opportunity from Department Of Homeland Security was posted on June 7, 2021. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

RFI FOR R&D - Biological Detection for the 21st Century (BD21) System of Systems (SoS)

Closed
70RWMD21RFI00000002Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

Active Opportunities Like This One

NAICS: 541714
New
Grant
Translational Centers Using Microphysiological Systems for Infectious Diseases (U54 Clinical Trial Not Allowed)
Solicitation # RFA-AI-28-012
The National Institute of Allergy and Infectious Diseases (NIAID) has issued solicitation RFA-AI-28-012 to establish a consortium of Translational Centers Using Microphysiological Systems for Infectious Diseases (TCMID). The primary objective is to refine and validate human tissue models using Microphysiological Systems (MPS) to a level consistent with regulatory qualifications, thereby promoting their adoption by product developers and reducing reliance on laboratory animals. This initiative aligns with NIH and FDA guidance on New Approach Methodologies (NAMs) to accelerate the development of safer medical interventions by capturing human variability and patient-specific characteristics. The program is structured around an Administrative Core, a Qualification Core, and Scientific Cores, with a heavy emphasis on technical readiness, reproducibility, and regulatory acceptance. Key deliverables include the validation of assays for specific endpoints and the submission of regulatory packages. Applicants must be domestic entities, as foreign organizations and foreign subawards are strictly prohibited. Required personnel must possess deep expertise in infectious diseases, MPS platforms, bioinformatics, and FDA submission processes. Applications are due by January 29, 2027, and must be submitted via the NIH ASSIST system or approved institutional system-to-system solutions. Evaluation is based on an overall impact score considering the project's significance, the suitability of the investigators, and the quality of the institutional environment. Mandatory application components include a Data Management and Sharing Plan and a Benchmarks and Timeline PDF not exceeding six pages. Awardees must also adhere to strict cybersecurity incident reporting guidelines, notifying HHS within 48 hours of any discovery.
National Institutes Of Health

POSTED

about 21 hours ago

DEADLINE

in 3 months
NAICS: 541714
New
Grant
Immune Tolerance Network (UM1 Clinical Trial Required)
Solicitation # RFA-AI-28-005
The National Institutes of Health, under the Department of Health and Human Services, is seeking applications through solicitation RFA-AI-28-005 to continue the Immune Tolerance Network (ITN). This cooperative agreement aims to develop tolerogenic therapies for immune-mediated disorders, specifically focusing on autoimmune diseases, allergic diseases and asthma, and the immune-mediated consequences of transplantation. The network operates through four integrated functional areas: Leadership, Clinical Operations, Core Laboratory, and Bioinformatics. Its primary objectives include designing and conducting clinical trials, performing integrated mechanistic studies, and sharing research results. Eligible applicants include small businesses and other for-profit organizations, though non-domestic entities are ineligible. Applications are evaluated based on scientific and technical merit, with a primary focus on significance and the likelihood of exerting a sustained influence on the research field. Key requirements include maintaining active registrations in SAM.gov, eRA Commons, and Grants.gov, as well as adhering to strict cybersecurity incident reporting and human subject protection protocols. The project requires a minimum effort of 3.6 person months per year for the PD/PI and mandates participation in a kick-off meeting in Bethesda, Maryland, and bi-annual steering meetings. Applications must follow specific page limits for the research strategy subsections and include detailed plans for clinical trial implementation, data management, and biorepository services.
National Institutes Of Health

POSTED

about 21 hours ago

DEADLINE

in 3 months
NAICS: 541714
New
Federal
Pre-Award Synopsis Texas Shield
Solicitation # DARPA-SN-27-07
The Defense Advanced Research Projects Agency (DARPA), through its Biological Technologies Office (BTO), intends to enter into an agreement with The University of Texas System consortium of universities for the Texas Shield Program. This integrated research initiative, identified by solicitation number DARPA-SN-27-07 and NAICS code 541714, focuses on developing autonomous and semi-autonomous medical technologies and scalable solutions for critical medical consumables. The primary goal is to support lifesaving medical care in contested, austere, and resource-limited environments. Key technical areas of focus include autonomous medical and robotic surgical systems, casualty evacuation, artificial-blood and supply innovation, AI-enabled clinical decision support, and mass-casualty science and simulation. This notice is a pre-award synopsis and is not a request for proposals or a competitive solicitation. Interested entities are invited to submit information by November 15, 2026, to TexasShieldxBTO@darpa.mil detailing their technical expertise, integrated research infrastructure, clinical-validation capabilities, and multi-institutional coordination capacity. Additionally, respondents must describe their consortium organizational structure, commercialization capabilities, facility clearance levels, and their ability to handle Controlled Unclassified Information. The government will not reimburse any costs associated with the preparation or submission of information in response to this notice.
Defense Advanced Research Projects Agcy

POSTED

5 days ago

DEADLINE

in 25 days
NAICS: 541714
New
Federal
Q--AMPLICON SEQUENCING SERVICES
Solicitation # 140G0226Q0047
Solicitation 140G0226Q0047 is a firm-fixed-price request for a Blanket Purchase Agreement (BPA) to provide next generation amplicon sequencing services for the USGS Upper Midwest Water Science Center’s Michigan Bacteriological Research Laboratory. The scope of work includes providing all equipment, labor, travel, and materials necessary to support research on bacterial pathogens, harmful algal blooms, microbial ecology, antibiotic resistance, and microbial source tracking. Key technical requirements include the use of Illumina MiSeq or AVITI sequencing technologies and the potential for library preparation for 16S V4 amplicon sequencing. The BPA has a total not-to-exceed value of 250,000 dollars with an estimated period of performance from September 17, 2026, to September 16, 2031. The award process prioritizes non-priced factors significantly over cost, focusing on the offeror's qualifications and technical performance. Evaluation criteria include a detailed listing of on-site equipment and calibration dates, personnel experience, internal quality assurance procedures, and a technical narrative not exceeding two pages. Performance will be executed in Lansing, Michigan, with delivery terms set as FOB Destination. Administrative requirements include electronic invoicing via the Internet Payment Platform and compliance with various federal regulations, including the Buy American Act and specific security prohibitions regarding telecommunications equipment. Proposals must be submitted to the USGS OAG Denver Acquisition Branch by September 11, 2026.
Ofc Of Acquisition Grants-Denver

POSTED

5 days ago

DEADLINE

in 3 days

General Info

NAICS

541714 - Research and Development in Biotechnology (except Nanobiotechnology)

Place of Performance

DC, USA

Set-Aside

NONE

Documents

7

BD21 Virtual Industry Day Participants List

PDF, Low priorityindustry-day
Low

BD21+Industry+Day+QAs+7June2021.pdf

PDF

BD21+RFI+for+Industry+Engagement.pdf

PDF

BD21+RFI+Questions_Answersv2.xlsx

XLSX

BD21+Virtual+Industry+Day+18MAR21_Final.pdf

PDF

Incoming+Foreign+National+Visit_CWMD_BD21.doc

DOC

Save+the+Date+BD21.pdf

PDF

AI Contract Breakdown

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Timeline

6 updates
PhaseClosed
Posted

Sources Sought

Notice updated

Notice details unchanged. Attachments may have changed.

Response Deadline

Deadline has passed

Notice updated

Notice details unchanged. Attachments may have changed.

Notice updated

The notice description changed. The point of contact changed.

Notice updated

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Notice updated

The notice description changed.

Notice updated

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Submission Closed

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Organization & Contact Information

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AgencyDepartment Of Homeland Security → Cwmd Acq Division
Contacts2 people available
OfficeWashington, DC, 20528, USA
Office AddressWashington, DC, 20528, USA
Contacts
Andrew Whittaker

Full Description

Show more
****************June 7, 2021 UPDATE************** Please see the attached Questions and Answers (Q&As) that were the result of the BD21 Industry Day. ****************March 26, 2021 UPDATE************** Per the BD21 Virtual Industry Day held on March 18, 2021, please see the attached presentation slides and the vendors attendees list. THIS IS A REQUEST FOR INFORMATION (RFI) ONLY. This RFI is issued solely for information and planning purposes; it does not constitute a Request for Proposal (RFP) or a promise to issue an RFP or Broad Agency Announcement (BAA). This RFI does not commit the Department of Homeland Security (DHS) Countering Weapons of Mass Destruction Office (CWMD) to contract for any supply or service. DHS CWMD is not at this time seeking proposals. Responders are advised that the CWMD will not pay any cost incurred in response to this RFI. All costs associated with responding to this RFI will be solely at the interested party's expense. Not responding to this RFI does not preclude participation in any future RFP or BAA. If a solicitation is released, it will be released via the Government-Wide Port of Entry (GPE) at (https://beta.sam.gov/). In order to receive an award from any resultant solicitation, should one be issued, the successful offeror must be registered in the System for Award Management (SAM). The SAM website is https://www.sam.gov. It is the responsibility of the potential responders to monitor the website for any information that may pertain to this RFI. The information provided in this RFI is subject to change and is not binding on the Government. All submissions become the property of the CWMD, and will not be returned. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organizations capabilities. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. Proprietary, confidential, privileged commercial or financial information submitted in the RFI response should be marked accordingly to ensure appropriate handling and disposition by the Government. No classified information shall be submitted in the RFI response. Do not use Government security classification markings. Do not mark the entire response as proprietary. Objective The Department of Homeland Security (DHS) Counter Weapons of Mass Destruction (CWMD) Office seeks to acquire a Biological Detection for the 21st Century (BD21) system of systems (SoS) to be defined in Section 4. BD21 is pursuing a next-generation capability to fulfill validated DHS biodetection capability gaps and support the eventual recapitalization of the fielded BioWatch capability. The BD21 team envisions an end state featuring a national biosurveillance system that includes real-time biodetection functionality to facilitate rapid response. The BD21 program has been approved to enter the Analyze / Select phase of the DHS acquisition lifecycle. The Analyze / Select phase aims to demonstrate technologies performance in the context of program requirements. To support this objective, the BD21 program management office (PMO) is requesting additional information from the industry on their ability to provide technologies that would satisfy BD21 notional requirements, as listed below. The BD21 PMO will use the information acquired from this Request for Information (RFI) to support the BD21 acquisition strategy. This RFI is focused on the integration efforts necessary for the types of interfaces and interactions between the Critical Technology Elements (CTEs) as defined in section 4, peripheral components, and their interactions. The BD21 program office is also interested in obtaining data regarding individual CTEs listed above. It is acceptable for offeror to resubmit documentation on those CTEs presented in response to previous solicitations. However, this effort centers around how to best bring together these components and explore their integration into a functional SoS. At this time, the focus is on an indoor SoS, but information on outdoor capabilities will be accepted. ... continued in document: "BD21 RFI for Industry Engagement Final" Please find the above information and more in the following documents: Document 1 - BD21 RFI for Industry Engagement Final Document 2 - Incoming Foreign National Visit_CWMD_BD21 Document 3 - Save the Date BD21

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