Schrodinger Suite License Renewal

DATE: April 14, 2014 CLOSING DATE: April 23, 2014 REQUISITION NO. 1132314 INTENDED SOURCE: Schrodinger LLC PERIOD of PERFORMANCE: July 14, 2014 - July 13, 2015 PLACE OF PERFORMANCE: Jefferson, AR The U.S. Food and Drug Administration intends to award a sole source purchase order to Schrodinger, LLC to provide Schrodinger Suite License Renewal. The Schrodinger Suite is a comprehensive package of chemical simulation software engineered specifically for the pharmaceutical and biotechnology research. The predictive power of Schrodinger's software accelerates research and development activities, and provides the precision tooling for the analysis needed to support research endeavors. This chemical simulation software must include the following: Visualization & Automation (Cloud, Job Control, Maestro 9.3, KNIME Extensions 1.5, PyMOL 1.5), Structure-Based Lead Discovery, Lead Optimization & ADME/Tox Prediction (CombiGiide 2.8, Glide 5.8, Induced Fit Docking (IFD), Prime MM-GBSA 2.0, OM-Polarized Ligand Docking (QPLD), SiteMap 2.6, Virtual Screening Workflow (VSW)), Protein Modeling & Refinement (Prime 3.1, PrimeX 1.9), Ligand Based & Pharmacophore Modeling (Core Hopping 1.2, Phase 3.4, QikProp 3.5), Cheminformatics & amp; QSAR (Canvas 1.5, R-Group Analysis (Stand-alone, Maestro, Canvas, Seurat), Scaffold Decomposition (Stand-alone, Maestro, Canvas, Seurat), Seurat 6.3), Medicinal Chemistry Applications (Maestro Elements 1.3), and Molecular Modeling & Simulations (ConfGen 2.4, Desmond 3.1, Epik 2.3, Jaguar and Jaguar pKa 7.9, LigPrep 2.5, MacroModel 9.9, QSite 5.8, Semiempirical NDDO Library (Maestro)). Schrodinger Suite is Windows 7 64-bit compatible. The period of performance for this requirement is for a base period of one year and four one-year option years. This procurement is being conducted in accordance with FAR Part 13.501(2)(i). This notice of intent is not a request for competitive quotations and no solicitation document is available and telephone requests will not be accepted. However, sources may submit descriptive literature, fully documenting their capability to perform these services, which will be considered by the Agency. Information can be sent to the U.S. Food and Drug Administration, Office of Acquisitions & Grants Services, Attn: Debbie Hammond, Contract Specialist, 5630 Fishers Lane HFA-500, Rockville, MD 20857. Information may be also faxed to 301-827-1044 or via email to the address below. Responses received will be evaluated, however; a determination not to compete the proposed procurement is based on responses(s) to this notice is solely within the discretion of the Government. If no responses are received, the FDA will proceed with a sole source award to Schrodinger, LLC., 101 S. W. Main Street, Portland, OR. The anticipated award date of this contract is July 14, 2014. No collect calls will be accepted. If you have questions regarding this Announcement, please contact Debbie Hammond at 240-402-7535 or via email dhammon1@oc.fda.gov.