This Combined Synopsis/Solicitation opportunity from Department Of Health And Human Services was posted on July 16, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.
Scientific analysis and mathematical modeling of clinical research data
Contract Overview
Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.
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This contract solicits scientific analysis and mathematical modeling of clinical research data under a Total Small Business Set-Aside (FAR 19.5), exclusively available to small businesses, with NAICS code 541690. The work requires development and validation of signal processing models to correlate SPG waveform features with cardiovascular function markers, demonstrate superior performance of SPG+PPG models over PPG-only approaches for noninvasive blood pressure estimation, and provide mechanistic interpretations of SPG signal origins in relation to cardiovascular physiology. The project is structured around six deliverables including a project plan, signal processing pipeline, clinical correlation report, blood pressure estimation validation, real-time demonstration package, and a final technology transfer report. The contract is awarded on a Firm Fixed Price basis using a Lowest Price Technically Acceptable (LPTA) evaluation methodology, where proposals must first pass two mandatory pass/fail gates: technical acceptability and acceptable or neutral relevant experience/past performance. Offerors must submit an eight-page combined narrative divided into two volumes—five pages for technical approach and three for past performance—and a separate pricing file detailing cost per deliverable. Compliance with stringent data security protocols is required, including use of FedRAMP Moderate or higher cloud infrastructure for Controlled Unclassified Information, adherence to HIPAA and HHS regulations, secure coding practices, and reliance solely on de-identified data provided by the government. All deliverables must meet exact reproducibility and accuracy standards, such as systolic and diastolic blood pressure estimation errors of no more than 7 mmHg and 5 mmHg respectively on holdout datasets, end-to-end latency under 100 ms at 60 Hz sampling, and code quality meeting agency standards. The contract duration is 12 months from award with biweekly emails, monthly calls, and quarterly written reports required, and the final report and technology transfer package due at month 12. The Offeror must include completed representations per FAR 52.212-3, resumes of key personnel including a Principal Investigator and senior scientist, and a detailed Minimum Performance Standards Checklist with cross-references. Proposals are due by July 17, 2026, at 11:00 PM EDT, with the contract administered by David Shen of the National Institutes of Health in Bethesda, Maryland.
General Info
Agency
NAICS
Place of Performance
Bethesda, MD, 20892, USASet-Aside
Timeline
Submission Closed
Organization & Contact Information
Full Description
July 16 Update: Posted FAQ, and extended deadline.
Attachments:
Combined Synopsis-Solicitation
Statement of Work
Evaluation Criteria
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