Scientific analysis and mathematical modeling of clinical research data

The National Institutes of Health, under the Department of Health and Human Services, is seeking qualified small businesses to provide scientific analysis and mathematical modeling of clinical research data through a total small business set-aside solicitation numbered 75N98026Q00752. This combined synopsis-solicitation, posted on July 8, 2026, requires responses by July 18, 2026, and is targeted at firms classified under NAICS code 541690 for other scientific and technical consulting services. The work will be performed at the agency’s location in Bethesda, Maryland, with all deliverables expected to meet rigorous standards for analytical accuracy and methodological rigor as outlined in the attached Statement of Work and Evaluation Criteria. Proposers must demonstrate expertise in handling complex clinical datasets, applying advanced statistical and computational models, and translating findings into actionable insights for biomedical research. All proposals must be submitted electronically via the SAM.gov portal, and the primary point of contact for inquiries is David Shen, reachable at david.shen@nih.gov. The evaluation process will assess technical approach, qualifications of personnel, past performance, and cost realism, with preference given to small businesses that can show proven experience in similar analytical projects within the health sciences. The contract will be awarded to one or more respondents who best meet the government’s requirements for transforming clinical research data into robust, reproducible, and scientifically valid models that support evidence-based decision-making. All work must comply with federal regulations and NIH standards for data integrity, security, and ethical use of research information.