System Components for 7T Small Animal MRI System (NINDS)

PRE-SOLICITATION NOTICE OF INTENT NON-COMPETITIVE Date Notice Posted: August 2, 2018 Date Notice Closes: August 9, 2018 Date Solicitation Issued: August 13, 2018 Date Solicitation Responses Due: August 20, 2018 Proposed Award Date: September 1, 2018 Project Title: System Components for 7T Small Animal MRI System (NINDS) Contracting Office: Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse (NIDA), Office of Acquisition (OA) 6001 Executive Blvd., Rockville, MD 20852 Contracting Officer: Jeffrey Brown, +1 (555) 000-0000, contact@example.gov Acquisition Authority: This acquisition is being conducted under Federal Acquisition Regulations (FAR) Part 13 - Simplified Acquisition Procedures, and the resultant contract award will include all applicable provisions and clauses in effect through Federal Acquisition Circular 2005-99 / June 15, 2018. North American Classification System (NAICS) Code: The intended procurement is classified under NAICS code 334510 - Electromedical and Electrotherapeutic Apparatus Manufacturing with a Size Standard of 1,250 employees. Product and Service Code: 66- Instruments & Laboratory Set-aside Status: Small Business set-aside restriction is not applicable. Competition Status: This requirement is posted as non-competitive. Non-Competitive (Single-sole Source (Including brand-name)) Determination: This notice of proposed acquisition is posted as an intent to award a purchase order on a non-competitive basis to Resonance Research, Inc. 5 Fortune Drive, Pinehurst Business Park, Billerica, MA 01821. The determination by the Government to award a contract without providing for full and open competition is based upon the market research conducted specifically producing no other sources of supply or service capable of achieving this Government requirement. Description of Requirement: The Cerebral Microcirculation Section (CMS) of the Laboratory of Functional and Molecular Imaging (LFMI) has a 7T small animal MRI system that was acquired in FY 2003. Some components of this system are nearing their useful end-of-life, and need to be upgraded. In particular, the system has been originally equipped with a set of gradient amplifiers that has recently started to fail frequently, introducing downtime to the operation of the MRI system and requiring constant repair. CMS needs to procure a new set of gradient amplifiers that will replace the existing set. The new set of gradient amplifiers should have significantly enhanced specifications when compared to the existing set. Together with the new set of gradient amplifiers, CMS needs a new gradient set that will be driven by the new gradient amplifiers, and allow CMS to obtain state-of-the-art imaging of small animals, including rodents and small primates. The purpose of this acquisition is to procure a new set of gradient amplifiers, a new gradient set, and associated cables and filters for the connection of these components to the MRI system. These components will modernize CMS 7T small animal MRI system and allow state-of-the-art imaging of small primates and rodents, in support of the research goals of CMS. The Salient characteristics are as follows: 1. MRI Gradient Power Amplifiers: a. General characteristics: The Gradient Power Amplifiers consist of 3 identitical modules capable of supplying the gradient set with current pulses and waveforms typical of MRI pulse sequences. The 3 modules are fed by a power supply, and the entire set is integrated into a single rack and cooled by a cooling system connected to the chilled water supply. b. Functional Specifications: At a minimum, the MRI gradient power amplifiers must meet the minimum set of specifications/performance standards: i. Isolated power supply - Mains: 380-480Vrms - 10%, 50/60Hz - Mains switch included - Power Factor Correction (PFC): unity power factor & low harmonics - Maximal mains power: 32kVA - Programmable bus voltage: 600Vdc...990Vdc. ii. Output performance - Output voltage (at Vbus max): - 940V - Output current: 630A peak, 230A rms - Maximum continuous output power: 5.3kW per axis, 13kW for all three axes - Tunable Load range: 220?H - 4.7mH iii. Output accuracy - High precision integrated current sensors - Bandwidth >10kHz - Settling time: error<1% after 100?s, <0.4% after 150?s, <0.1% after 250?s - Initial offset: negligible (auto-zero) - Drift: typical offset 5mA/C, typical gain 10ppm/C - Propagation delay: <70?s - Total harmonic distortion: <0.4% at 230A rms/200Hz, <0.8% at 230A rms/1kHz iv. Control / communication / monitoring - Differential analog current set-point - RS422 control interface - Ethernet service interface - Synchronous operation via distributed clock - Digital control loop tuning - Analog monitoring: output current,current set-point, output voltage, bus voltage, current error v. Error protection & diagnostics - Built in self-test - Advanced diagnostics via control interface - Front panel LCD and status LEDs per module - Fault tolerant fans with tacho - Output overcurrent protection (peak & RMS) - Mains error detection - Water leakage detection - Integral temperature protection vi. Mechanical - Cabinet size: no larger than 615x825x1800mm (WxDxH) - Liquid cooled vii. Regulatory & environmental - Reliability: MTBF > 50khr. - Lifetime: >10 years - RoHS & REACH compliant 2. MRI Gradient Set: a. General characteristics: The MRI Gradient Set consists of a shielded, MRI-compatible set of 3 gradient coils (X, Y and Z) with an integrated set of shim coils and integrated cooling. The gradient set will operate inside CMS's existing small-animal 7T/30 cm magnet, and will interface with the MRI console and Gradinet Power Amplifiers via a set of filters specified in item #3 below. b. Functional Specifications: At a minimum, the MRI gradient set must meet the minimum set of specifications/performance standards: i. Gradient set dimensions: OD: <300 mm; ID: >170 mm. ii. Gradient strength: minimum of 450 mT/m @ 500 A maximum current (gain 0.9 mT/m/A) iii. Maximum Operating Current/Voltage: 500 A/1000 V iv. Water cooling: minimum 6 lpm v. Maximum weight: 250 kg vi. Integrated temperature sensors : minimum of 6 sensors vii. Min. heat dissipation: 3.5 kW for ?T=25 - C viii. Maximum Rise Time: 120 ?s to peak gradient in all 3 axes. ix. Minimum Slew rate: 4000 T/m/s x. Minimum RMS current, all axes simultaneously: 100 A xi. Linearity for a 100 mm DSV X/Y: - 3% Z: - 2.5% xii. Shielding quality: > 99 % xiii. Orthogonality: 90 - 1 degree xiv. Residual Eddy Currents (before pre-emphasis): < 0.5 % measured 1ms after 20ms trapezoidal pulse xv. Integrated Shim System with a minimum of 12 shim channels rated at 10 A maximum DC current and the following minimum strengths in Hz/cm2/A: Z2, 180; Z3, 20; ZX/ZY, 150; C2/S2, 100; Z2X/Z2Y, 20; ZC2/ZS2, 25; C3/S3, 10; xvi. Cable Connections: Compatible with BRUKER AV3 Schaultbau 2 connector. 3. RF Filters: a. General Characteristics: The RF filters are electronic devices that operate in a filter plate in the penetration panel that sits at the wall between the MRI console room and the magnet room. Their function is to prevent RF irradiation from passing from the console room to the magnet room, where it could interfere with image quality. These RF filters are critical elements when interfacing the gradient power amplifiers to the gradient set. b. Functional Specifications: At a minimum, the RF filters must meet the minimum set of specifications/performance standards: i. Penetration panel material: stainless steel ii. Low-pass cutoff frequency of 30MHz with minimum attenuation of -100 dB iii. Filters: high capacitance, 500A; 2000V; 900 A peak iv. Number of channels: 3 dual filters v. Cooling of filters by forced air via AC fans 4. Temperature and Water Flow Monitoring System: a. General Characteristics: This is a monitoring/protection system that fits inside a standard 19 wide sub-rack chassis and monitors the current operating temperature of the RF filters, of the gradient set and integrated shims, and of the gradient chiller. If any of the operating temperatures exceed their setpoint, the monitoring system sends an interlock signal to the MRI console preventing its use, so that the gradient set and RF filters are protected from being damaged by over temperature conditions. b. Functional Specifications: At a minimum, the Temperature and Water Flow Monitoring System must: i. System continuously reads temperature of the gradient RF filters and of the integrated gradient/shim set. temperature monitoring system ii. System features a 6 channel RTD temperature scanner/monitor iii. System features an RS-232 programming cable iv. System features an interlock cable able to connect to the existing MXW shim power supply v. Water flow switch (external water supply required) vi. System features monitoring of water temperature and flow of the gradient chiller vii. System features interlock cables to the gradient chiller viii. System allows Emergency shutdown of the console in case of over temperature. 5. Water Chiller-Circulator: a. General Characteristics: The Water Chiller-Circulator is a machine that circulates chilled water to keep the gradient set operating temperature within an optimal range, preventing the gradient set from overheating during its operation. b. Functional Specifications: At a minimum, the water chiller-circulator must have: i. An integrated cooling coil to keep water refrigerated ii. A circulator capable of pumping refrigerated water at a rate of 6 gallons per minute iii. Enough volume / heat capacity to dissipate in excess of 1KW of heat at constant temperature iv. Water Cooling Capacity of 20 Kilowatts minimum Period of Performance: Anticipated start date in FY18. The exact period of performance is to be determined. Summary Statement: This notice is NOT a request for competitive proposals or quotations It is anticipated that a solicitation will be issued on or about August 13, 2018. Interested parties may request a copy of the solicitation or identify their interest and capability by contacting the Contracting Officer specified in this announcement. All responses must be received by August 9, 2018 at 12:00 pm, Eastern Time. Responses must be submitted electronically to Jeffrey Brown, contact@example.gov, and must reference the solicitation number NIHDA201800342, on your electronic request. FAX requests are not accepted. In addition, the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All respondents must have an active registration in the System for Award Management (SAM) www.sam.gov. Closing Statement: - All responsible sources may submit response which, if timely received, must be considered by the agency.