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TECHNOLOGY LICENSING OPPORTUNITY: Multi-Channel Atomic Magnetometer (MCAM)

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S-133667Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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The Multi-Channel Atomic Magnetometer (MCAM) is a breakthrough non-cryogenic optical quantum sensor that delivers SQUID-level sensitivity to ultra-faint biomagnetic signals using a single shared vapor cell and optical system to generate up to 16 independent sensing channels simultaneously, eliminating the need for multiple independent sensor units. Unlike traditional systems that rely on liquid helium-cooled SQUIDs, MCAM operates at room temperature using a large alkali-metal vapor cell, broad pump and probe laser beams, and a photodiode array to detect magnetic field-induced polarization rotations via the Faraday effect. Buffer gas within the cell isolates spatial regions behind each photodiode pixel, enabling high-resolution, two-dimensional magnetic field mapping without cryogens, significantly reducing costs and complexity. The rear-mirror optical design shortens the sensor-to-source distance, enhancing spatial resolution, while fiber-optic coupling allows modules to be tiled into conformal helmet or surface arrays that adapt to patient anatomy, supporting applications from brain and heart imaging to pediatric and point-of-care diagnostics. MCAM’s architecture scales efficiently to hundreds of channels and is compatible with adjustable bias coils and multiple alkali-metal and buffer-gas combinations, making it highly flexible for diverse configurations. It achieves sensitivity in the low tens of femtotesla per root hertz at low frequencies while drastically cutting per-channel expenses by sharing critical components across all channels. Ongoing development aims to shrink the effective sensing volume from centimeter to micrometer scale, opening the door to cellular-level magnetic imaging—capabilities unattainable by current cryogenic or conventional room-temperature systems. Applications span medical diagnostics such as magnetoencephalography and magnetocardiography, cancer detection via magnetic particle imaging, low-field MRI, geomagnetic surveying, and fundamental physics research. The technology, protected by U.S. Patent 11,105,865 and currently at TRL 4, is available for licensing through Los Alamos National Laboratory, offering exclusive and non-exclusive opportunities to commercialize a platform poised to revolutionize biomagnetic sensing by making high-performance imaging accessible, mobile, and cost-effective.

General Info

Room-temperature, multi-channel biomagnetic sensor with SQUID-level sensitivity, no cryogens, scalable to hundreds of channels.

Agency

Department Of Energy → Triad - DOE ContractorView Agency

NAICS

334516 - Analytical Laboratory Instrument ManufacturingView NAICS

Place of Performance

Los Alamos, NM, 87545, USA

Set-Aside

NONE

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Organization & Contact Information

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AgencyDepartment Of Energy → Triad - DOE Contractor
Contacts2 people available
OfficeColumbus, OH, 43201, USA
Organization / Agency
Department Of Energy → Triad - DOE Contractor
View Agency Profile
Office AddressColumbus, OH, 43201, USA
Contacts
Kathleen McDonald
Lindsay Augustyn

Full Description

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Unlike conventional multichannel atomic magnetometers that require one vapor cell and one optical system for each sensing channel, the patented Multi-Channel Atomic Magnetometer (MCAM) architecture from Los Alamos National Laboratory replaces many independent atomic magnetometers with a single shared vapor cell and optical system that simultaneously generates multiple independent sensing channels. MCAM is a non-cryogenic multi-channel optical quantum sensor in a single module that captures ultra-faint biomagnetic signals from the brain, heart and other sources with sensitivity approaching that of the cryogenic SQUID-based systems that have defined the field for decades. MCAM delivers that performance at roughly one-tenth the per-channel cost without a drop of liquid helium. The module pairs one large alkali-metal vapor cell with broad pump and probe laser beams read out by a photodiode array, providing 16 independent sensing channels in a single housing, scaling into helmet-style arrays of hundreds of channels, and flexing around the patient rather than forcing the patient into a fixed cryogenic dewar. Together, these attributes more easily allow for magnetoencephalography, magnetocardiography and magnetic-particle imaging while accelerating overall magnetic imaging workflows. Ongoing development is aimed at extending the sensing architecture from the centimeter scale characterized in the current prototype toward micrometer-scale spatial resolution, opening a path into cellular-scale magnetic imaging that current cryogenic and room-temperature arrays cannot address.


How it Works


The MCAM module operates on the spin-exchange relaxation-free (SERF) regime, in which atomic spins of alkali-metal atoms inside a large, sealed vapor cell are aligned by a circularly polarized broad pump laser beam through optical pumping and then interrogated by a linearly polarized broad probe beam propagating along a nearly parallel path. An external magnetic field of interest tilts the aligned atomic spins by an angle proportional to the field strength, and that tilt rotates the polarization plane of the probe beam through the Faraday effect; a photodiode array reads the optical rotation simultaneously at multiple points across the cell, with each photodiode pixel reporting on its own localized sensing volume. A buffer gas inside the cell restricts atomic motion so that the small cell volumes behind each pixel behave as independent sensing channels, a rear mirror folds the beams back through the cell to shorten the stand-off distance to the magnetic source, and transparent Pyrex wire heaters hold the cell at the operating temperature needed for SERF operation.


Technology Description


The patented shared-cell architecture generates multiple independent sensing channels from a single vapor cell, a single pump beam, a single probe beam, and a single detector array. A pair of broad, co-propagating laser beams, one for optical pumping and the other for probing, traverses the shared vapor cell to manipulate the internal atomic spins, converting the local magnetic field distribution into a spatially resolved optical signal that is read out by a multi-pixel photodetector. Because the buffer gas inside the cell restricts atomic diffusion, each pixel of the detector reports on its own small, spatially distinct region of the cell; therefore, the single module yields a two-dimensional map of the local magnetic field rather than a single-point measurement. Operation in the SERF regime, together with an integrated heating and shielding arrangement and a fold-back optical geometry that shortens the distance from the sensing volume to the magnetic source, sets the sensitivity floor in the low tens of femtotesla per root hertz at low frequency. A development path has been identified to reduce the effective sensing-volume scale from the roughly 1 cm per-channel footprint of the current prototype toward the 1 μm range, which would extend the platform from whole-organ mapping into micro-scale magnetic imaging regimes.


Architecturally, the MCAM module is engineered for arrays. Because all channels within a single module share one vapor cell, one laser pair, and one optics assembly, the per-channel parts count and tuning effort drop sharply versus designs that stack many single-channel sensors. Fiber-optic coupling between the laser sources and each sensor head lets modules be repositioned independently, so many modules can be tiled into a conformal helmet or surface array that adapts to head or torso shape and supports configurations that rigid large-cell predecessors cannot accommodate. The design is compatible with several alkali-metal and buffer-gas options and with per-module bias coils that allow each module to be tuned individually inside a larger array.


Advantages


  • Development path toward micrometer-scale spatial resolution, a roughly four-order-of-magnitude improvement over the current centimeter-scale prototype and an enabler of cellular-scale magnetic imaging
  • Sensitivity at the low tens of femtotesla per root hertz, comparable to cryogenic SQUID arrays, while using a warm vapor, non-cryogenic architecture
  • Roughly tenfold per-channel cost reduction by sharing one vapor cell, one laser pair and one optics set across 16 channels
  • No liquid cryogens, eliminating recurring cryogen costs and simplifying siting, maintenance and shielding
  • Fiber-coupled, repositionable sensor heads that conform to the patient rather than forcing the patient into a fixed dewar
  • Scalable into helmet-style arrays of hundreds of channels, including a size-adjustable pediatric configuration
  • Shorter sensor-to-source stand-off via rear-mirror beam folding, sharpening spatial resolution of biomagnetic sources

Market Applications


  • Medical Diagnostic Imaging (magnetoencephalography systems for epilepsy, stroke and neurodegenerative workups; magnetocardiography for arrhythmia and ischemia screening)
  • Pediatric and Adaptive Neuroimaging (size-adjustable MEG helmets, point-of-care brain monitoring)
  • Micro-scale Biomagnetic Imaging (single-neuron and small-circuit brain activity mapping, high-resolution cardiac tissue mapping)
  • Cancer Diagnostics (magnetic nanoparticle imaging for tumor localization and targeted-therapy tracking)
  • Magnetic Resonance Imaging (low-field/ultra-low field, portable MRI, functional brain imaging)
  • Sensing (low-frequency antennas for underground or undersea links, geomagnetic surveying)
  • Instrumentation (fundamental physics, biomagnetism laboratories, multichannel sensor R&D)


Development Status: TRL 4


U.S. Patent No. 11,105,865


LA-UR-26-25904



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NAICS: 334516
Federal
Precision Ultrasonic Transducer ManufacturingThe contract calls for the precise manufacturing of high-frequency, tunable ultrasonic transducers designed specifically for integration into the UltraSep platform’s resonance-locked separation system, requiring advanced engineering to meet strict performance criteria under demanding operational conditions. These transducers must be capable of precise frequency adjustment to maintain resonance with the system’s separation mechanism, ensuring consistent and efficient material partitioning, with production expected to adhere to rigorous quality and repeatability standards suited for industrial-scale deployment. Performance of this subcontract is centered in Los Alamos, New Mexico, under the oversight of Triad, a contractor to the Department of Energy, with full compliance to NAICS code 334516 for other electronic component manufacturing. The opportunity was posted on July 8, 2026, and responses are due by October 1, 2026, indicating a targeted procurement timeline for qualified manufacturers with demonstrated expertise in piezoelectric systems and high-frequency transducer fabrication. All work must align with the technical requirements of the UltraSep platform, and potential bidders must possess the capability to deliver calibrated, reliable units suitable for integration into a sensitive, resonance-dependent separation process.
Analytical Laboratory Instrument Manufacturing

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NAICS: 541714
Federal
TECHNOLOGY LICENSING OPPORTUNITY: Platform to Accelerate Discovery of Tailored Industrial Enzymes (PAD-TIE)The PAD-TIE platform, developed by NREL and Los Alamos National Laboratory, is a high-throughput screening system designed to rapidly identify and optimize enzymes capable of breaking down polyethylene terephthalate (PET) plastic under industrially relevant conditions. Unlike traditional methods that test enzymes one at a time, PAD-TIE evaluates tens of thousands of enzyme variants simultaneously, measuring their activity, stability, and production efficiency in a single process, eliminating costly purification steps and reducing time-to-identification. The system operates at the optimal temperature for PET degradation and is validated in lab-scale bioreactors that mimic real-world recycling environments, enabling the conversion of plastic waste into reusable monomers without harsh chemicals or excessive energy use. With a Technology Readiness Level of 6, the platform is a fully functional prototype with all components tested, and three U.S. patents are pending, making it a mature and protected innovation ready for commercial adoption. PAD-TIE is positioned to serve a broad range of industries including plastic recycling, waste management, polymer manufacturing, and sustainable materials development. Its adaptability allows customization for different PET compositions, additives, and processing conditions, ensuring compatibility with existing infrastructure. The platform’s efficiency and scalability offer a cost-effective solution for scaling enzymatic plastic degradation at an industrial level. Los Alamos National Laboratory is seeking industry partners through exclusive or non-exclusive licensing agreements to further develop and deploy the technology, with applications spanning bioremediation, bioplastics, and closed-loop recycling systems. Interested parties must respond by October 1, 2026, and inquiries should be directed to the provided licensing contacts. The technology is available for commercialization under a non-set-aside procurement with a NAICS code of 541714, and performance will occur in Los Alamos, New Mexico.
Research and Development in Biotechnology (except Nanobiotechnology)

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