The NIDDK Disorders of Gastrointestinal Interoception Consortium (DGIC) Scientific Data Research Center (U24 Clinical Trial Not Allowed)

The National Institutes of Health, through the Department of Health and Human Services, is soliciting applications for the NIDDK Disorders of Gastrointestinal Interoception Consortium (DGIC) Scientific Data Research Center under solicitation RFA-DK-28-214. The primary objective of this initiative is to establish a central hub that identifies mechanisms linking altered gastrointestinal interoception to dysmotility and symptoms, identifies disease or response biomarkers, and leverages advanced technologies to discover novel therapeutic targets. The selected center will be responsible for data coordination and management, regulatory compliance through the establishment of a single Institutional Review Board, biospecimen coordination, administrative support for the steering committee, and the dissemination of resources via FAIR-compliant databases and portals. The program intends to fund one award with a total program funding of 1.5 million dollars, though individual application budgets are limited to 950,000 dollars in direct costs. The maximum project period is five years. Applications will be evaluated through a multi-stage process involving initial peer review based on significance, investigator qualifications, and innovation, followed by a second-level review by a national Advisory Council or Board. Eligible applicants must maintain active registrations in the System for Award Management and eRA Commons. Recipients are required to adhere to strict cybersecurity guidelines, including notifying HHS of any incidents within 48 hours, and must comply with all NIH Data Management and Sharing policies.