Tissue Function and Critical Quality Attribute (CQA) Assessment

The contract seeks development and performance of assays to assess the functional integrity of preserved tissues, focusing on metabolic activity, electrophysiological function, and structural stability, alongside the identification and validation of critical quality attributes necessary for clinical use. These assessments are essential to ensure that tissues retain viable, reproducible, and therapeutically relevant properties after preservation, directly supporting translational readiness and regulatory compliance for clinical deployment. The effort is classified as a subcontract under NAICS code 541380 and is issued by the Advanced Research Projects Agency for Health within the Department of Health and Human Services, with performance expected in Washington. The solicitation was posted on April 24, 2026, and responses are due by May 12, 2026, at 4:59 PM Eastern Time, indicating a tight window for proposal submission. The work is pivotal to advancing preservation technologies for tissue-based therapies and requires technical expertise in functional tissue evaluation and quality assurance frameworks aligned with clinical standards.