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This Government Contract opportunity from Department Of Health And Human Services was posted on April 24, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

Special Notice for Technology InteGrator and AcceleratoR (TIGAR)

Closed
ARPA-H-SN-26-142Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541715
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Request for Proposal (RFP) - Resilient Missile Warning Tracking (RMWT) Low Earth Orbit (LEO) Ground Entry Points (GEPs)
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Solicitation # 80GSFC27R0015
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1 day ago

DEADLINE

in about 1 month
NAICS: 541715
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AN41--Pre-clinical Research: Behavioral Assessment
Solicitation # 36C24127Q0035
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241-NETWORK Contract Office 01 (36C241)

POSTED

1 day ago

DEADLINE

in 3 days
NAICS: 541715
New
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Sources Sought: Domestically Produced Hand and Measuring Tools (ACC-DTA CSO Amend 40)
Solicitation # W912CH26S0001
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W6QK Acc- Dta

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DEADLINE

N/A

AI Contract Overview

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The Advanced Research Projects Agency for Health (ARPA-H), under the Health Science Futures Office, is issuing a Special Notice to announce the upcoming Innovative Solutions Opening (ISO) for the Technology InteGrator and AcceleratoR (TIGAR) exploratory topic, with the official solicitation expected to be posted on SAM.gov on April 22, 2026. This initiative seeks groundbreaking research to develop temperature-flexible preservation methods for complex tissues and organs, aiming to eliminate reliance on cryogenic storage by enabling functional preservation — including cell viability, tissue structure, and critical physiological attributes — for at least 30 days under practical conditions ranging from -80°C to 25°C. Proposals must integrate novel approaches in artificial intelligence, advanced materials, and biotechnology to enable scalable, on-demand preservation applicable to research and clinical settings, with a focus on high-risk, high-reward concepts that align with ARPA-H’s mission of transformative health innovation. The program operates under an 18-month two-phase structure, with a mandatory go/no-go decision after Phase 1, and a total funding cap of $2 million per award. All potential proposers are required to register for and attend the mandatory TIGAR Proposers’ Day webinar, with registration closing on May 12, 2026, and the webinar sessions scheduled for May 14 or May 20, 2026. Failure to attend renders a proposal ineligible. The official solicitation, ARPA-H-SOL-26-144, will be published on SAM.gov and will contain definitive submission requirements, including the need to submit both a solution video and a full proposal, though specific formatting, page limits, and file types have not been detailed in this pre-solicitation notice. Evaluation will prioritize technical innovation, feasibility, potential impact on regenerative medicine and reduction of animal testing, and scalability, with award decisions expected to follow a trade-off analysis rather than lowest-price technically acceptable criteria. The place of performance is Washington, DC, and while no contract clauses, federal acquisition regulation provisions, or detailed packaging and labeling standards are specified in this notice, proposers must comply with all requirements outlined in the official ISO. Administrative and technical inquiries should be directed to [email hidden], and no set-aside provisions are in effect, meaning all entities are eligible to compete.

General Info

ARPA-H announces TIGAR solicitation April 22, 2026, with Proposers’ Day and May 12 deadline.

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

Washington, DC, USA

Set-Aside

NONE

Documents

2

ARPA-H Special Notice 26-142 TIGAR Webinar Announcement

PDF, Low priorityspecial-notice
Low

ARPA-H-SN-26-142_TIGAR+SN.pdf

PDF

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Timeline

1 update
PhaseClosed
Posted

special-notice

Notice updated

The notice description changed.

Response Deadline

Deadline has passed

Submission Closed

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)
Contacts1 person available
OfficeWashington, DC, 20005, USA
Office AddressWashington, DC, 20005, USA
Contacts
See Description Section

Full Description

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This Special Notice (SN) is intended to alert the scientific community to a newly approved Advanced Research Projects Agency for Health (ARPA-H) solicitation and notify potential proposers of an associated Proposers’ Day (PD) sponsored by the Health Science Futures (HSF) Office. Under the cognizance of the HSF Office, ARPA-H is publishing an Innovative Solutions Opening (ISO) for the Technology InteGrator and AcceleratoR (TIGAR) Exploratory Topic on April 22nd, 2026.  


Please monitor SAM.gov for updates to the ISO ARPA-H-SOL-26-144. 


For additional PD details see the attached notice ARPA-H-SN-26-142.


Amendment 1


Amendment 1 of the SN updated the webinar and webinar registration dates, as well as relevant links.

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Solicitation # ARPA-H-SOL-26-160
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Simulation-augmented, Real-time Platform Adaptive Seamless Trials (SURPASS)
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