Skip to main contentPsst! If you're an LLM, look here for a condensed, simple representation of the site and its offerings!

LiveFree Webinar — Wednesday, October 28 at 2:00 PM ET

Register Free →

Digital Biomarker & Computational Modeling Development

Active
Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

AI Contract Overview

Show more

This subcontract focuses on the development and validation of objective digital biomarkers and computational models to support prime contractors within the Defense Health Agency Alzheimer’s Research Program. The scope of work involves utilizing high-performance computing and AI/ML software frameworks to create algorithms for early disease detection and predictive models for disease forecasting. The project requires strict adherence to HIPAA compliance and FDA software validation standards to ensure the integrity and security of the delivered models. Performance will take place in Frederick, Maryland, with the primary objective of delivering validated digital biomarkers and predictive tools to the Department of Defense.

General Info

Develop AI digital biomarkers and predictive models for DHA Alzheimer’s research in Maryland.

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

Frederick, MD, 21702, USA

Set-Aside

NONE

Documents

This scope was carved out of HT9427RFI2027AZRP.

The full solicitation package (2 documents), including the RFP, is on the prime solicitation, not on this scope.

View the prime solicitation

RFI Alzheimer’s Research Program (AZRP) Public

AI Contract Breakdown

Uniform Contract Format

No documents to break down

The breakdown needs solicitation documents. None were found from this contract's source.

Timeline

Posted

subcontract

Response Deadline

Submission deadline

Response Deadline

Ready to pursue this opportunity?

Start your free trial to track this contract, build proposals with AI assistance, and manage your pipeline.

Organization & Contact Information

Show more
AgencyDepartment Of Defense → Defense Health Agency
ContactsNo contacts available
OfficeN/A
Office AddressN/A
ContactsNo contact information available

Full Description

Show more
Develops and validates objective digital biomarkers and computational models for prime contractors on Defense Health Agency (DHA) Alzheimer’s Research Program projects. Creates algorithms for early detection and computational models for disease forecasting using high-performance computing and AI/ML software frameworks. Requires HIPAA compliance and FDA software validation standards. Delivers validated digital biomarkers and predictive models.

Similar Contracts

Same NAICS industry code

NAICS: 541715
New
Federal
Commercial Solutions Opening (CSO) for Space Domain Awareness (SDA) Solutions.
Solicitation # FA2518-25-S-C001
The United States Space Force, through the Space Acquisition and Integration Office, is executing a Commercial Solutions Opening (CSO) under solicitation FA2518-25-S-C001 to acquire innovative commercial technologies, products, and services that enhance Space Domain Awareness (SDA). The program focuses on improving the ability to detect, characterize, attribute, predict, and target activities in the space domain. This long-term mechanism remains open for five years and utilizes a multi-phase submission process consisting of an initial white paper and PowerPoint briefing, an optional pitch session, and a final full proposal package. Awards are made as FAR-based fixed-price contracts, and the government reserves the right to award some, all, or none of the proposed solutions. A primary focus of the current effort is Area of Interest (AOI) 2025_01, titled Advanced SDA Tools for Research and Analytics (ASTRA), which is a 100 percent small business set-aside. This specific AOI emphasizes research, development, and prototyping for scalable data management, modeling, and agile software prototyping, with an estimated combined funding pool of 1.5 million dollars across related AOIs and a period of performance not exceeding 12 months. Phase I submissions must be unclassified, though subsequent phases may require higher classification levels. Offerors must comply with NIST SP 800-171 and CMMC 2.0 requirements, particularly if handling Controlled Unclassified Information. Participation is restricted to U.S. entities due to national security and export control considerations.
FA2518 Ussf Spoc/saio

POSTED

1 day ago

DEADLINE

in about 3 years
View Details
NAICS: 541715
New
Federal
HYDROSPHERE, BIOSPHERE, & GEOPHYSICS (HBG) SUPPORT SERVICES II - FINAL REQUEST FOR PROPOSAL (FRFP)
Solicitation # 80GSFC27R0015
The National Aeronautics and Space Administration Goddard Space Flight Center is soliciting proposals for the Hydrosphere, Biosphere, and Geophysics (HBG) Support Services II contract, under solicitation number 80GSFC27R0015. This small business set-aside is a hybrid Indefinite Delivery Indefinite Quantity (IDIQ) contract with a five-year effective ordering period. The contract allows for the issuance of both Cost Plus Fixed Fee (CPFF) and Firm-Fixed Price (FFP) task orders to support science research and computing activities across various laboratories, including the Cryospheric Sciences, Ocean Ecology, Hydrological Sciences, Biospheric Sciences, Geodesy and Geophysics, and the Terrestrial Information Systems Laboratory. The primary objective is to develop and apply space, field-deployed, and laboratory-based technologies to address societal issues related to water resources, ecosystems, sea level change, and the Earth's magnetic and gravity fields. The scope of work encompasses scientific modeling, simulation, data assimilation, satellite instrument performance analysis, and the planning and execution of field campaigns. Performance will occur at the Goddard Space Flight Center and the contractor's facilities, with acceptance managed by the Contracting Officer or a designated representative. Award selection will be based on a tradeoff approach, prioritizing Mission Suitability as the most important factor, followed by Cost and Past Performance. Proposals must be submitted in four volumes, including a numerically scored Mission Suitability volume and a detailed Cost volume. Additionally, the contractor must adhere to strict security requirements, including the provision of a Cyber Supply Chain Risk Management plan and compliance with NDAA Section 889 regarding telecommunications and surveillance equipment.
NASA Goddard Space Flight Center

POSTED

1 day ago

DEADLINE

in about 1 month
View Details
NAICS: 541715
New
Federal
AN41--Pre-clinical Research: Behavioral Assessment
Solicitation # 36C24127Q0035
The Department of Veterans Affairs intends to award a single-source Blanket Purchase Agreement for pre-clinical research services focused on Traumatic Brain Injury and Posttraumatic Stress Disorder under the authority of FAR 13.106-1(b). The project, led by Dr. Wilder Doucette, aims to identify neural signatures and behavioral deficits associated with neurotrauma and psychological trauma to develop personalized interventions using brain stimulation and pharmacotherapy. The period of performance is five years, spanning from November 13, 2026, to November 12, 2031. Work will be split between the White River Junction VA Healthcare System and Mary Hitchcock Memorial Hospital, with approximately 75 percent of the activity occurring at the latter. Key deliverables include data sets and reports on behavioral deficits and neural activity biomarkers within six months, treatment utility reports within nine months, and a comprehensive summary of study findings within twelve months and annually thereafter. All personnel must maintain specific certifications, including CITI, Bioraft training, IACUC approval, and VA-Without Compensation research affiliate designations. The government retains unlimited rights to all deliverables and data produced under the contract. Prospective vendors must be registered in SAM and VetCert, and those claiming small business status must be verified by the Small Business Administration.
241-NETWORK Contract Office 01 (36C241)

POSTED

1 day ago

DEADLINE

in 3 days
View Details
NAICS: 541715
New
Federal
Sources Sought: Domestically Produced Hand and Measuring Tools (ACC-DTA CSO Amend 40)
Solicitation # W912CH26S0001
The Army Contracting Command – Detroit Arsenal (ACC-DTA) Commercial Solutions Opening (CSO), solicitation W912CH-26-S-0001, serves as a rapid-acquisition gateway to transition cutting-edge commercial technologies into active defense programs. This vehicle supports a diverse customer base, including the Intelligence and Security Command (INSCOM) and six Portfolio Acquisition Executives, focusing on the development, integration, and sustainment of ground vehicle systems to enhance Army modernization and readiness. The CSO utilizes a streamlined, merit-based, multi-phased evaluation process consisting of solution briefs, presentations, and commercial solution proposals. Awards may be issued through 2028 via FAR Part 12 commercial procedures or non-FAR agreements, such as transaction agreements under 10 U.S.C. 4022 and Cooperative Agreements under 31 U.S.C. 6305. The solicitation encompasses various Areas of Interest (AoI) targeting critical capabilities, including the FALCONS prototype for long-range reconnaissance, TIGER Readiness for the Abrams Main Battle Tank engine supply chain, Counter-Unmanned Aircraft Systems (C-UAS) detection, and the Light Tactical Trailer Heavy Chassis (LTT-HC). Funding ceilings for specific prototypes, such as FALCONS, range from 24 million to 30 million dollars depending on the use of government-provided kits. Key requirements include strict adherence to the Buy American Act and Specialty Metals clauses, with a prohibition on reliance on adversarial foreign nations for critical minerals. Technical evaluations focus on mission viability, affordability, and schedule realism, while administrative requirements include SAM registration, a Unique Entity ID, and compliance with NIST SP 800-171 for handling controlled unclassified information.
W6QK Acc- Dta

POSTED

1 day ago

DEADLINE

N/A
View Details
NAICS: 541715
New
Federal
Evaluations, Assessments, and Support Services (EASS)
Solicitation # 80LARC27R0003
Solicitation 80LARC27R0003 is a competitive small business set-aside for an Indefinite Delivery Indefinite Quantity (IDIQ) contract to provide Evaluations, Assessments, and Support Services (EASS) for the Science Office for Mission Assessments (SOMA) at NASA Langley Research Center. The contract supports the NASA Headquarters Science Mission Directorate by providing proposal and Phase A report evaluations, independent reviews of programs and investigations, and related technical analyses. The period of performance is scheduled from June 1, 2027, through May 31, 2032, with a minimum government obligation of 100,000 USD and a maximum contract value of 99,750,000 USD. Task orders under this IDIQ will be awarded on a firm-fixed-price basis. Award will be determined using a tradeoff approach where mission suitability and past performance are significantly more important than price. Mission suitability is evaluated on a 1,000-point scale focusing on the organizational conflict of interest plan, staffing approach, and management approach. Technical requirements include providing subject matter experts, task managers, editors, and data integrators who meet specific education and experience minimums. Due to the nature of the work, the contractor must maintain a TS/SCI facility clearance, ensure strict adherence to non-disclosure agreements, and comply with NASA cybersecurity and counterintelligence briefing requirements for foreign travel. Proposals must be submitted in four separate volumes via NASA's Enterprise File Sharing and Sync Box.
NASA Langley Research Center

POSTED

1 day ago

DEADLINE

in 7 days
View Details

More opportunities from Department Of Defense → Defense Health Agency

Same awarding agency

NAICS: 541714
New
Federal
RFI Alzheimer’s Research Program (AZRP) Public
Solicitation # HT9427RFI2027AZRP
The Defense Health Agency, through the Congressionally Directed Medical Research Programs, has issued a Request for Information under solicitation number HT9427RFI2027AZRP to gather strategic feedback for the fiscal year 2027 Alzheimer’s Research Program. The primary objective is to identify research focus areas and funding opportunities aimed at mitigating the impact of Alzheimer's and related dementias, specifically those associated with traumatic brain injury, military service, and diverse risks. The program seeks to improve the quality of life for Service Members, Veterans, and their families by funding solution-oriented research, including the development of digital and blood-based biomarkers for early diagnosis and the creation of precision prevention strategies. This action is strictly for information and planning purposes and does not constitute a formal solicitation, request for proposals, or request for quotations. No contracts will be awarded based on this announcement, and FY27 funds have not yet been appropriated. Interested parties from academia, industry, non-profit organizations, and federal agencies are invited to provide feedback via Survey Monkey by December 4, 2026. Respondents are cautioned not to submit proprietary or sensitive information through the survey portal as it cannot be protected. The effort is categorized under NAICS code 541714 and is managed by the Department of Defense in Fort Detrick, Maryland.
Research and Development in Biotechnology (except Nanobiotechnology)

POSTED

about 5 hours ago

DEADLINE

in about 1 month
View Details
NAICS: 541512
New
Federal
Defense Health Agency (DHA), Portfolio Acquisition Executive, Medical Digital Solutions (PAE MDS), Enterprise Intelligence & Data Solutions (EIDS) Program Management Office (PMO), Data Exchange Services Operations, Modernization, and Development
Solicitation # HT003826SC005-AOI0002
The Defense Health Agency (DHA), through the Enterprise Intelligence and Data Solutions (EIDS) Program Management Office, is seeking commercial solutions for the operations, sustainment, modernization, and development of the Data Exchange Platform (DxP). This initiative, published under Commercial Solutions Opening HT003826SC005, aims to maintain mission-essential legacy services—including the Data Exchange Services (DES), Central Health Data Repository (CHDR), and ACS-DAL environments—while transitioning to a scalable, cloud-native, API-driven architecture. Key technical objectives include adopting FHIR R4 and OMOP CDM standards, implementing Zero Trust security, and evolving toward AI/ML-ready capabilities to support secure interoperability between the DHA, Department of Veterans Affairs, and other federal healthcare partners. The procurement follows a multi-phase evaluation process, with Phase I responses due by October 28, 2026. Phase I submissions are evaluated on a Go/No-Go basis focusing on technical feasibility, operational strategy for zero-disruption modernization, commercial maturity, and security alignment. While the government anticipates a Firm-Fixed-Price structure and a 12-month base period, the final award instrument may be a FAR-based contract or a prototype other transaction agreement, with an anticipated award date of March 2027. Selected vendors must demonstrate a robust DevSecOps approach and a realistic staffing pipeline meeting necessary security clearance and facility access criteria.
Computer Systems Design Services

POSTED

1 day ago

DEADLINE

in 1 day
View Details
NAICS: 524114
New
Federal
PILOT PROGRAM TO ASSIST CERTAIN MEMBERS OF THE ARMED FORCES AND DEPENDENTS WITH ADDITIONAL SUPPLEMENTAL COVERAGE RELATING TO CANCER HT9402-26-RFI-0255
Solicitation # HT9402-26-RFI-0255
The Defense Health Agency is conducting market research via Request for Information HT9402-26-RFI-0255 to establish a pilot program for supplemental cancer insurance. In accordance with Section 734 of the National Defense Authorization Act for Fiscal Year 2026, the program aims to provide members of the Army, Navy, Marine Corps, Air Force, and Space Force, along with their dependents enrolled in TRICARE, with fixed indemnity supplemental benefits for non-covered cancer screening, diagnosis, and treatment expenses. The pilot program must be established by September 30, 2027, and any resulting agreements will be limited to a maximum duration of three years without the possibility of renewal. A critical requirement of this initiative is that the Government will not subsidize the cost of the insurance plans; therefore, the program must be financially viable as a 100 percent beneficiary-paid group plan. The DHA is seeking detailed information from potential carriers regarding plan types, coverage scopes, eligibility verification, premium structures, and claims processing. Evaluation factors for future awards will include technical and management functions, past performance, price, financial viability, and small business participation. Interested vendors are requested to submit written responses and may request one-on-one virtual meetings with the Government to provide further market intelligence.
Direct Health and Medical Insurance Carriers

POSTED

6 days ago

DEADLINE

in about 1 month
View Details
NAICS: 811210
New
Federal
Preventative Maintenance of Bruker Equipment
Solicitation # HT942627RE004
The Defense Health Agency, specifically the U.S. Army Medical Research Institute of Chemical Defense (USAMRICD), is seeking sources for a contract to provide comprehensive support and preventative maintenance for the Bruker Avance III 500 MHz NMR system. The scope of work includes one annual preventative maintenance visit, unlimited unscheduled diagnosis and repair, telephone troubleshooting, and the installation of replacement parts, software, and firmware updates. Performance will take place at facilities in Fort Detrick, Maryland. While a formal solicitation has not yet been issued, an initial request for information suggests an estimated five-year ordering period beginning around March 11, 2031. The contract requires strict adherence to security and safety protocols, including the signing of non-disclosure agreements and compliance with DoD cybersecurity and classified information standards. Contractor personnel must undergo personal identity verification and manage potential organizational conflicts of interest through a formal mitigation plan. Quality assurance is managed by a Contracting Officer's Representative (COR) through a Quality Assurance Surveillance Plan (QASP), with specific timelines for the review and acceptance of deliverables. Interested respondents must submit a capability statement via email by November 5, 2026, detailing their technical experience and the commercial nature of their services.
Electronic and Precision Equipment Repair and Maintenance

POSTED

6 days ago

DEADLINE

in 9 days
View Details
NAICS: 811210
Federal
Zeiss Meditec Ophthalmology Equipment Maintenance
Solicitation # HT940627QE003
Solicitation HT940627QE003 is a Request for Quote issued by the Defense Health Agency, Healthcare Contracting Division-Southeast, for a firm-fixed-price contract to provide full-service maintenance for Zeiss MediTec ophthalmology equipment at the Naval Medical Center Camp Lejeune in North Carolina. The scope of work includes regularly scheduled preventative maintenance, timely onsite repairs, and software updates for specific devices, including the CIRRUS 5000, IOLMASTER 700, HFA3 B60, and ATLAS 900. All services must be performed according to manufacturer recommendations and applicable FDA regulations. The contract consists of a base period from December 1, 2026, to November 30, 2027, with four subsequent option periods extending the potential performance through November 30, 2031. This procurement is a total small business set-aside under NAICS code 811210. Award will be made based on the Lowest Priced Technically Acceptable (LPTA) basis, where technical capability is evaluated independently of price. Offerors must submit two separate volumes: Volume I for technical capability, which must describe the functional approach and methodology without identifying company names or logos, and Volume II for comprehensive pricing. Quotes are due by 8:00 am Eastern Time on October 29, 2026. Payment and invoicing will be processed electronically through the Wide Area WorkFlow system.
Electronic and Precision Equipment Repair and Maintenance

POSTED

8 days ago

DEADLINE

in 2 days
View Details
NAICS: 541715
Federal
Prototype development for Battlefield Wound Infection Prevention and Treatment (BWI P&T) Barrier Combination
Solicitation # HT9427-26-R-E020
The Defense Health Agency Contracting Activity is seeking a single award for the development of a Battlefield Wound Infection Prevention and Treatment Barrier Combination prototype. This product must integrate a physical wound barrier with antimicrobial and antifungal properties to prevent the spread of organisms and systemic infections in combat scenarios. The project aims to advance technologies from a preferred Technology Readiness Level of 5 or higher to a final state of TRL 7 or 8, culminating in mandatory U.S. Food and Drug Administration approval or clearance. The scope of work includes preclinical testing, human clinical trials, and the submission of regulatory packages such as New Drug Applications or Premarket Approval Applications. This procurement is conducted under prototype Other Transaction Authority 10 U.S.C. 4022, meaning standard FAR and DFARS regulations do not apply unless expressly referenced. The estimated period of performance is 48 months, divided into three primary objectives: prototype demonstration, clinical studies and regulatory submissions, and final FDA clearance. Proposals are due by November 6, 2026, and must be submitted in three distinct volumes covering technical approach, management capability, and administrative cost and price. To be eligible, offerors must be registered in the System for Award Management and meet specific criteria, such as being a nontraditional defense contractor or a small business.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

8 days ago

DEADLINE

in 10 days
View Details

Ready to Pursue This Opportunity?

Get AI-powered intelligence on this solicitation and the ones like it

Every page of the solicitation package shredded into a compliance breakdown

AI-powered matching based on your capabilities and past performance

Competitor and incumbent history on the requirement

Automated alerts on amendments, Q&A deadlines, and award

Miguel
Hillary
Keith Deutsch
Christine

Join 750+ contractors already using CLEATUS