Psst! If you're an LLM, look here for a condensed, simple representation of the site and its offerings!

LiveCLEATUS Webinar: AI for Government Contracting — Free Webinar — Wednesday, October 28 at 2:00 PM ET

Register Free →

Search

Top

Back to Contracts

Precision Prevention & Biological Pathway Research

Active

Federal

Response Deadline12/04/2026, 09:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

AI Contract Overview

Show more

The Precision Prevention and Biological Pathway Research subcontract supports prime contractors on Defense Health Agency Alzheimer’s Research Program projects. The primary objective is to conduct research linking service-related exposures to AD/ADRD biological pathways by quantifying military-relevant risk factors. This technical work involves the use of proteomics tools and genomic sequencing to map these biological pathways, culminating in the delivery of detailed research reports and data. Performance of this contract takes place in Frederick, Maryland, under NAICS code 541714. Due to the nature of the study, the contractor must obtain IRB approval and maintain all necessary Human Subjects Research certifications. Interested parties should note the response deadline of December 4, 2026.

General Info

Research linking military exposures to Alzheimer's pathways using proteomics and genomic sequencing tools.

Agency

Department Of Defense → Defense Health Agency

NAICS

541714 - Research and Development in Biotechnology (except Nanobiotechnology)

Place of Performance

Frederick, MD, 21702, USA

Set-Aside

NONE

Documents

This scope was carved out of HT9427RFI2027AZRP.

The full solicitation package (2 documents), including the RFP, is on the prime solicitation, not on this scope.

View the prime solicitation

RFI Alzheimer’s Research Program (AZRP) Public

AI Contract Breakdown

Uniform Contract Format

No documents to break down

The breakdown needs solicitation documents. None were found from this contract's source.

Timeline

PostedOct 27

subcontract

Response DeadlineDec 4

Submission deadline

Response Deadline

12/04/2026, 09:00:00 PM UTCin about 1 month

Ready to pursue this opportunity?

Start your free trial to track this contract, build proposals with AI assistance, and manage your pipeline.

Organization & Contact Information

Show more

AgencyDepartment Of Defense → Defense Health Agency

ContactsNo contacts available

OfficeN/A

Organization / AgencyDepartment Of Defense → Defense Health Agency

Office AddressN/A

ContactsNo contact information available

Full Description

Show more

Performs research linking service-related exposures to AD/ADRD biological pathways for prime contractors on Defense Health Agency (DHA) Alzheimer’s Research Program projects. Quantifies military-relevant risk factors and maps biological pathways using genomic sequencing and proteomics tools. Requires IRB approval and Human Subjects Research certifications. Delivers research reports and data linking exposures to pathways.

Similar Contracts

Same NAICS industry code

Blood-Based Biomarker Validation & ScalingThis subcontract focuses on the validation and scaling of blood-based biomarkers to support prime contractors within the Defense Health Agency Alzheimer’s Research Program. The scope of work involves performing detailed laboratory analysis of blood samples, validating the sensitivity and specificity of assays, and establishing scalable testing protocols. These operations must utilize Simoa equipment and biobanking systems while adhering strictly to GLP standards and maintaining CLIA certification. The project is managed under the Department of Defense and is centered in Frederick, Maryland. The primary objective is the delivery of validated, scalable biomarker assays and protocols to advance research goals. Interested parties should note the response deadline of December 4, 2026, and the classification of the work under NAICS code 541714.

Defense Health Agency

POSTED

about 5 hours ago

DEADLINE

in about 1 month

RFI Alzheimer’s Research Program (AZRP) Public

Solicitation # HT9427RFI2027AZRP

The Defense Health Agency, through the Congressionally Directed Medical Research Programs, has issued a Request for Information under solicitation number HT9427RFI2027AZRP to gather strategic feedback for the fiscal year 2027 Alzheimer’s Research Program. The primary objective is to identify research focus areas and funding opportunities aimed at mitigating the impact of Alzheimer's and related dementias, specifically those associated with traumatic brain injury, military service, and diverse risks. The program seeks to improve the quality of life for Service Members, Veterans, and their families by funding solution-oriented research, including the development of digital and blood-based biomarkers for early diagnosis and the creation of precision prevention strategies. This action is strictly for information and planning purposes and does not constitute a formal solicitation, request for proposals, or request for quotations. No contracts will be awarded based on this announcement, and FY27 funds have not yet been appropriated. Interested parties from academia, industry, non-profit organizations, and federal agencies are invited to provide feedback via Survey Monkey by December 4, 2026. Respondents are cautioned not to submit proprietary or sensitive information through the survey portal as it cannot be protected. The effort is categorized under NAICS code 541714 and is managed by the Department of Defense in Fort Detrick, Maryland.

Defense Health Agency

POSTED

about 5 hours ago

DEADLINE

in about 1 month

Traumatic Brain Injury and Psychological Health Research Program Public Request for Information

Solicitation # HT9427RFI2027TBIPHRP

Defense Health Agency

POSTED

about 5 hours ago

DEADLINE

in about 2 months

Request for Proposals (RFP) - BARDA Vaccine Medical Countermeasures for Pandemic Influenza Preparedness & Response

Solicitation # 75A50126R00001_RFP_NPIVS_27

The Biomedical Advanced Research and Development Authority (BARDA) is soliciting proposals for the Vaccine Medical Countermeasures for Pandemic Influenza Preparedness and Response Program. The objective is to maintain a permanent readiness posture against high-threat influenza and other viruses with pandemic potential. Selected contractors will provide vaccines, antigens, and adjuvants, and generate necessary analytical, nonclinical, clinical, and chemistry, manufacturing, and controls data for FDA submission to support rapid regulatory decisions. To be eligible, offerors must produce vaccines against influenza strains with pandemic potential and demonstrate successful manufacturing experience by holding a U.S. influenza vaccine license or having submitted a Biologics License Application for a seasonal or pandemic influenza vaccine. The government intends to award contracts to four offerors based on the Highest Technically Rated Offerors with a Fair and Reasonable Price methodology. Evaluation factors include capabilities, past performance, and price, with capabilities being the most significant. The contract structure consists of a 60-month base period and a 60-month option period, with a minimum guarantee of 50,000 dollars. Key requirements include the development of comprehensive manufacturing, business continuity, and supply continuity plans, as well as adherence to strict ASPR security and FDA CGMP standards. Performance will be managed through individual task orders and BPA call orders, with invoicing conducted quarterly via the Department of Treasury Invoice Processing Platform.

Barda - Aspr / Daappo / Barda Dcma

POSTED

DEADLINE

USDA SBIR/STTR Topic 8.2 — Plant Production and Protection - Biology

Solicitation # USDA-NIFA-TOPIC-8.2

The USDA National Institute of Food and Agriculture is soliciting proposals under Topic 8.2 for Plant Production and Protection - Biology. This initiative focuses on advancing crop production and protection through the development of innovative plant breeding methods, diagnostic technologies for diseases, and the creation of new food and non-food crop plants. Research efforts are directed toward improving plant characteristics to mitigate biotic and abiotic stresses, developing new genotypes for commercial applications, and creating tools to support the health of natural and domesticated pollinators. This opportunity is a total small business set-aside under the SBIR/STTR mandate, restricting eligibility to companies with fewer than 500 employees. Managed by the United States Department of Agriculture, the program is led by Dr. Christopher Philips. Interested parties can find further details and application guidelines through the NIFA website.

National Institute of Food and Agriculture

POSTED

DEADLINE

Quantitative Analysis of Longitudinal MR Images

Solicitation # 75N98027R00005

Solicitation 75N98027R00005 is a Sources Sought notice issued by the National Institute on Aging (NIA) to identify qualified companies capable of performing quantitative analysis of longitudinal Magnetic Resonance (MR) images. The project supports the Baltimore Longitudinal Study of Aging (BLSA) by processing 300 newly acquired MR datasets to characterize brain aging trajectories and identify predictors of cognitive decline and Alzheimer’s disease. The selected contractor will provide specialized, non-commercial services to deliver global and regional tissue volumes, lesion quantification, and machine learning-derived scores, such as SPARE-AD, while ensuring longitudinal consistency with data acquired since 1994. The anticipated contract will be a firm fixed price award with a period of performance of one year. Key deliverables include quantitative volumetric results, intermediate processing files, and registration maps for PET overlay, submitted every six months, concluding with a final report. Technical requirements emphasize the use of established image analysis tools and adherence to FISMA/FedRAMP-aligned data security controls to protect participant confidentiality. Interested respondents must submit a capability statement by November 9, 2026, to Contract Specialist Sneha Singh. The submission must be limited to ten pages and include the company's Unique Entity ID, NAICS code 541714, professional qualifications of personnel, and any applicable GSA schedules or government-wide acquisition contracts. Small businesses are encouraged to respond to this market research effort to help the government determine the appropriate acquisition method.

National Institutes Of Health Olao

POSTED

DEADLINE

Q--AMPLICON SEQUENCING SERVICES

Solicitation # 140G0226Q0047

The Department of the Interior, through the USGS OAG Denver Acquisition Branch, is soliciting quotations for a Blanket Purchase Agreement (BPA) to provide next-generation amplicon sequencing services for the Michigan Bacteriological Research Laboratory. The agreement has a not-to-exceed value of $250,000 over a five-year period of performance from September 17, 2026, to September 16, 2031. The scope of work includes non-personal services such as library preparation for 16S V4 amplicon sequencing, library pooling, and sequencing using Illumina MiSeq or AVITI platforms to support research on bacterial pathogens, antibiotic resistance, and microbial ecology. Key deliverables include demultiplexed raw data and reporting metrics, with a required delivery turnaround of 60 business days from sample receipt. Award decisions will be based on technical and priced factors, with non-priced factors carrying significantly more weight. Technical evaluations will focus on the contractor's on-site equipment, personnel experience, quality control procedures, business establishment, and a capabilities narrative. Offerors must also provide two customer references from the last five years. The contract is subject to various federal regulations, including specific security prohibitions regarding certain telecommunications equipment and the requirement for electronic invoicing through the Invoice Processing Platform System. Quotations are due by November 5, 2026, and must be submitted via email to the primary point of contact.

Ofc Of Acquisition Grants-Denver

POSTED

DEADLINE

ARPA-H Emerging Health Innovators (EHI) Initiative

Solicitation # ARPA-H-SOL-26-150

The Advanced Research Projects Agency for Health (ARPA-H) Emerging Health Innovators (EHI) initiative, solicitation ARPA-H-SOL-26-150, seeks to identify and engage early-career investigators to develop cutting-edge biomedical, health, and community-engaged research. This opportunity is open to researchers from academic, nonprofit, and industry organizations, provided the Principal Investigator is within eight years of completing their first terminal degree. The initiative covers 16 specific topic areas, including AI in life sciences, brain stimulation, and human tissue platforms. Awards are issued as Other Transaction (OT) agreements, which are not subject to the Federal Acquisition Regulation (FAR). The selection process is a two-step submission involving an initial anonymized Solution Summary and a subsequent Full Proposal for selected candidates. Successful awards have a total value not to exceed 1,050,000 dollars over a three-year period, consisting of a 24-month base period capped at 700,000 dollars and an optional 12-month Director's Award period capped at 350,000 dollars. Payments are structured as fixed payments triggered by the completion of 12 discrete, measurable milestones. Full proposals are evaluated based on technical merit, innovativeness, feasibility, alignment with the ARPA-H mission to accelerate health outcomes, and price reasonableness. Administrative requirements include mandatory registration in SAM.gov and the use of the ARPA-H Solutions site for all submissions. Proposers must adhere to strict formatting templates for technical and management proposals, milestone schedules, and national policy requirements, including disclosures regarding organizational conflicts of interest and research security. Performance is monitored through a formal inspection and acceptance process where the government reviews deliverables within 14 calendar days. The tentative award start date is June 30, 2027, with full proposals due by February 10, 2027.

Advanced Research Projects Agency For Health (arpa-H)

POSTED

DEADLINE

In Vivo Biodistribution Studies and Bioluminescence ImagingThis subcontract, titled In Vivo Biodistribution Studies and Bioluminescence Imaging, supports biotechnology projects for the Department of Veterans Affairs at the Harry S Truman Memorial Veterans Hospital. The selected provider will conduct animal studies to evaluate AAV vector specificity and off-target transduction. Key technical responsibilities include administering vectors to animal models, utilizing bioluminescence imaging via IVIS to track localization, and performing tissue harvesting for qPCR analysis to generate comprehensive biodistribution data reports. The work will be performed in Columbia, Missouri, and requires strict adherence to AAALAC and FELASA health standards. This opportunity is categorized under NAICS code 541714 and is managed by Rpo East. Interested parties should note the response deadline of November 4, 2026.

Rpo East (36C24E)

POSTED

DEADLINE

AAV Vector Binding and Internalization Testing (Kidney Tissue)This subcontract, issued by the Department of Veterans Affairs Rpo East for biotechnology projects at the Harry S Truman Memorial Veterans Hospital, involves specialized laboratory testing to verify the binding and internalization of AAV vectors. The selected provider will be responsible for preparing kidney tissue slices, incubating them with modified AAV vectors, and utilizing qPCR platforms, Agilent Fragment Analyzers, and fluorescence microscopy to analyze efficiency. All work must be performed in BSL-2 facilities, and the contractor is required to hold BSL-2 certification. The primary deliverable for this engagement is the provision of detailed validation reports focusing on internalization rates and binding affinity. The project is categorized under NAICS code 541714 and is based in Columbia, Missouri. Interested parties must respond by November 4, 2026.

Rpo East (36C24E)

POSTED

DEADLINE

Chemical, Biological, Radiological, and Nuclear (CBRN) Medical Countermeasure (MCM) Participant Basic Agreement (PBA)

Solicitation # W911SR-26-R-HEAL

The Capability Program Executive for Chemical, Biological, Radiological, and Nuclear Defense (CPE CBRND) is establishing the Chemical, Biological, Radiological, and Nuclear (CBRN) Medical Countermeasure (MCM) Participant Basic Agreement (PBA) ecosystem. This continuous, open announcement seeks to build a network of pre-qualified partners to accelerate the development, testing, and fielding of next-generation medical defense solutions. The program focuses on two primary pillars: host-targeted resilience, which targets critical host systems like neurological and respiratory pathways to enhance physiological protection, and threat-targeted neutralization, which focuses on broad-spectrum countermeasures for prophylaxis and acute treatment. Priority is given to candidates designed for austere environments, featuring environmental stability without cold-chain reliance and simplified administration routes such as oral or intranasal delivery. The government is inviting two types of participants: MCM Development Collaborators, ranging from Phase I products through FDA licensure, and MCM Development Support Collaborators, such as CROs and CDMOs specializing in preclinical testing, cGMP manufacturing, and regulatory submissions. Interested parties must submit a white paper of no more than five pages detailing their product descriptions, efficacy data, regulatory status, and manufacturing capabilities. Acceptance into the PBA enables the subsequent award of project orders under the authority of 10 U.S.C sections 4021, 4022, and 4023. These agreements are not subject to the Competition in Contracting Act of 1984. All prospective awardees must be registered in the System for Award Management (SAM) database to receive payment.

POSTED

DEADLINE

AJ12--Development/Production - Kidney GEC-Specific AAV Vector

Solicitation # 36C24E27Q0009

The Department of Veterans Affairs is issuing a Sources Sought notice to identify capable vendors for the development and production of a kidney glomerular endothelial cell specific adeno-associated virus AAV vector. This project, funded by a VA ORD Merit award, aims to create a homing peptide enabled vector platform to target the glomerular endothelium to treat kidney injury and disease while reducing off target transduction. The scope of work is divided into three primary tasks: the engineering and incorporation of targeting peptides into the AAV capsid, testing vector binding and internalization in kidney tissue slices, and evaluating the specificity and efficiency of the modified vector through bioluminescence imaging and in vivo biodistribution studies. Qualified contractors must possess extensive onsite resources, including BSL 2 laboratories, specialized DNA and RNA facilities, and advanced instrumentation such as the Agilent Fragment Analyzer and various qPCR platforms. Vendors must demonstrate proven success in animal and human cell vector delivery and maintain full compliance with AAALAC and FELASA health standards. The government requires quarterly reporting, weekly videoconferences, and biannual face to face meetings. All generated data will be subject to Government Purpose Rights, and contractors must adhere to strict federal records management and information security protocols. Interested parties must submit a capability statement, relevant literature, and socio economic status details under NAICS 541714 by November 4, 2026.

Rpo East (36C24E)

POSTED

DEADLINE

More opportunities from Department Of Defense → Defense Health Agency

Same awarding agency

Digital Biomarker & Computational Modeling DevelopmentThis subcontract focuses on the development and validation of objective digital biomarkers and computational models to support prime contractors within the Defense Health Agency Alzheimer’s Research Program. The scope of work involves utilizing high-performance computing and AI/ML software frameworks to create algorithms for early disease detection and predictive models for disease forecasting. The project requires strict adherence to HIPAA compliance and FDA software validation standards to ensure the integrity and security of the delivered models. Performance will take place in Frederick, Maryland, with the primary objective of delivering validated digital biomarkers and predictive tools to the Department of Defense.

Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

about 5 hours ago

DEADLINE

in about 1 month

Werfen/Instrumentation Laboratories Equipment Maintenance & Supplies

Solicitation # 12415247

Electronic and Precision Equipment Repair and Maintenance

POSTED

about 5 hours ago

DEADLINE

Defense Health Agency (DHA), Portfolio Acquisition Executive, Medical Digital Solutions (PAE MDS), Enterprise Intelligence & Data Solutions (EIDS) Program Management Office (PMO), Data Exchange Services Operations, Modernization, and Development

Solicitation # HT003826SC005-AOI0002

The Defense Health Agency (DHA), through the Enterprise Intelligence and Data Solutions (EIDS) Program Management Office, is seeking commercial solutions for the operations, sustainment, modernization, and development of the Data Exchange Platform (DxP). This initiative, published under Commercial Solutions Opening HT003826SC005, aims to maintain mission-essential legacy services—including the Data Exchange Services (DES), Central Health Data Repository (CHDR), and ACS-DAL environments—while transitioning to a scalable, cloud-native, API-driven architecture. Key technical objectives include adopting FHIR R4 and OMOP CDM standards, implementing Zero Trust security, and evolving toward AI/ML-ready capabilities to support secure interoperability between the DHA, Department of Veterans Affairs, and other federal healthcare partners. The procurement follows a multi-phase evaluation process, with Phase I responses due by October 28, 2026. Phase I submissions are evaluated on a Go/No-Go basis focusing on technical feasibility, operational strategy for zero-disruption modernization, commercial maturity, and security alignment. While the government anticipates a Firm-Fixed-Price structure and a 12-month base period, the final award instrument may be a FAR-based contract or a prototype other transaction agreement, with an anticipated award date of March 2027. Selected vendors must demonstrate a robust DevSecOps approach and a realistic staffing pipeline meeting necessary security clearance and facility access criteria.

Computer Systems Design Services

POSTED

DEADLINE

Bruker Avance III NMR Replacement Parts SupplyThis subcontract focuses on the supply of genuine, OEM-certified replacement parts and non-consumable components specifically compatible with Bruker Avance III 500 MHz NMR magnets and consoles. These materials are intended for prime contractors supporting projects for the Defense Health Agency under the Department of Defense. The contract requires delivery of all components via standard commercial carriers to Fort Detrick in Frederick, Maryland. Classified under NAICS code 423440, the opportunity was posted on October 21, 2026, with a response deadline set for November 5, 2026.

Other Commercial Equipment Merchant Wholesalers

POSTED

DEADLINE

Bruker Avance III 500 MHz NMR System Technical Support and MaintenanceThis subcontract focuses on providing technical support and maintenance for Bruker Avance III 500 MHz NMR systems supporting Defense Health Agency projects at Fort Detrick in Frederick, Maryland. The scope of work includes performing annual on-site preventative maintenance visits, conducting unscheduled repairs, providing telephone troubleshooting, and implementing necessary software and firmware updates to ensure the systems remain fully functional. To execute these services, the contractor must utilize certified technicians specifically trained in Bruker magnets and consoles. Key deliverables include the continuous operational readiness of the NMR systems and the submission of detailed service reports documenting all maintenance and repair activities.

Electronic and Precision Equipment Repair and Maintenance

POSTED

DEADLINE

PILOT PROGRAM TO ASSIST CERTAIN MEMBERS OF THE ARMED FORCES AND DEPENDENTS WITH ADDITIONAL SUPPLEMENTAL COVERAGE RELATING TO CANCER HT9402-26-RFI-0255

Solicitation # HT9402-26-RFI-0255

The Defense Health Agency is conducting market research via Request for Information HT9402-26-RFI-0255 to establish a pilot program for supplemental cancer insurance. In accordance with Section 734 of the National Defense Authorization Act for Fiscal Year 2026, the program aims to provide members of the Army, Navy, Marine Corps, Air Force, and Space Force, along with their dependents enrolled in TRICARE, with fixed indemnity supplemental benefits for non-covered cancer screening, diagnosis, and treatment expenses. The pilot program must be established by September 30, 2027, and any resulting agreements will be limited to a maximum duration of three years without the possibility of renewal. A critical requirement of this initiative is that the Government will not subsidize the cost of the insurance plans; therefore, the program must be financially viable as a 100 percent beneficiary-paid group plan. The DHA is seeking detailed information from potential carriers regarding plan types, coverage scopes, eligibility verification, premium structures, and claims processing. Evaluation factors for future awards will include technical and management functions, past performance, price, financial viability, and small business participation. Interested vendors are requested to submit written responses and may request one-on-one virtual meetings with the Government to provide further market intelligence.

Direct Health and Medical Insurance Carriers

POSTED

DEADLINE

in about 1 month

Preventative Maintenance of Bruker Equipment

Solicitation # HT942627RE004

The Defense Health Agency, specifically the U.S. Army Medical Research Institute of Chemical Defense (USAMRICD), is seeking sources for a contract to provide comprehensive support and preventative maintenance for the Bruker Avance III 500 MHz NMR system. The scope of work includes one annual preventative maintenance visit, unlimited unscheduled diagnosis and repair, telephone troubleshooting, and the installation of replacement parts, software, and firmware updates. Performance will take place at facilities in Fort Detrick, Maryland. While a formal solicitation has not yet been issued, an initial request for information suggests an estimated five-year ordering period beginning around March 11, 2031. The contract requires strict adherence to security and safety protocols, including the signing of non-disclosure agreements and compliance with DoD cybersecurity and classified information standards. Contractor personnel must undergo personal identity verification and manage potential organizational conflicts of interest through a formal mitigation plan. Quality assurance is managed by a Contracting Officer's Representative (COR) through a Quality Assurance Surveillance Plan (QASP), with specific timelines for the review and acceptance of deliverables. Interested respondents must submit a capability statement via email by November 5, 2026, detailing their technical experience and the commercial nature of their services.

Electronic and Precision Equipment Repair and Maintenance

POSTED

DEADLINE

Zeiss Meditec Ophthalmology Equipment Maintenance

Solicitation # HT940627QE003

Solicitation HT940627QE003 is a Request for Quote issued by the Defense Health Agency, Healthcare Contracting Division-Southeast, for a firm-fixed-price contract to provide full-service maintenance for Zeiss MediTec ophthalmology equipment at the Naval Medical Center Camp Lejeune in North Carolina. The scope of work includes regularly scheduled preventative maintenance, timely onsite repairs, and software updates for specific devices, including the CIRRUS 5000, IOLMASTER 700, HFA3 B60, and ATLAS 900. All services must be performed according to manufacturer recommendations and applicable FDA regulations. The contract consists of a base period from December 1, 2026, to November 30, 2027, with four subsequent option periods extending the potential performance through November 30, 2031. This procurement is a total small business set-aside under NAICS code 811210. Award will be made based on the Lowest Priced Technically Acceptable (LPTA) basis, where technical capability is evaluated independently of price. Offerors must submit two separate volumes: Volume I for technical capability, which must describe the functional approach and methodology without identifying company names or logos, and Volume II for comprehensive pricing. Quotes are due by 8:00 am Eastern Time on October 29, 2026. Payment and invoicing will be processed electronically through the Wide Area WorkFlow system.

Electronic and Precision Equipment Repair and Maintenance

POSTED

DEADLINE

Prototype development for Battlefield Wound Infection Prevention and Treatment (BWI P&T) Barrier Combination

Solicitation # HT9427-26-R-E020

The Defense Health Agency Contracting Activity is seeking a single award for the development of a Battlefield Wound Infection Prevention and Treatment Barrier Combination prototype. This product must integrate a physical wound barrier with antimicrobial and antifungal properties to prevent the spread of organisms and systemic infections in combat scenarios. The project aims to advance technologies from a preferred Technology Readiness Level of 5 or higher to a final state of TRL 7 or 8, culminating in mandatory U.S. Food and Drug Administration approval or clearance. The scope of work includes preclinical testing, human clinical trials, and the submission of regulatory packages such as New Drug Applications or Premarket Approval Applications. This procurement is conducted under prototype Other Transaction Authority 10 U.S.C. 4022, meaning standard FAR and DFARS regulations do not apply unless expressly referenced. The estimated period of performance is 48 months, divided into three primary objectives: prototype demonstration, clinical studies and regulatory submissions, and final FDA clearance. Proposals are due by November 6, 2026, and must be submitted in three distinct volumes covering technical approach, management capability, and administrative cost and price. To be eligible, offerors must be registered in the System for Award Management and meet specific criteria, such as being a nontraditional defense contractor or a small business.

Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

DEADLINE

Ready to Pursue This Opportunity?

Get AI-powered intelligence on this solicitation and the ones like it

Every page of the solicitation package shredded into a compliance breakdown

AI-powered matching based on your capabilities and past performance

Competitor and incumbent history on the requirement

Automated alerts on amendments, Q&A deadlines, and award

Join 750+ contractors already using CLEATUS