Fast Assessment of Solutions, Therapeutics, Pharmaceuticals, and SupplieS (FASTPASS) Innovative Solutions Opening

The Advanced Research Projects Agency for Health (ARPA-H) is seeking multiple awardees under Other Transaction Agreements for the Fast Assessment of Solutions, Therapeutics, Pharmaceuticals, and SupplieS (FASTPASS) program. The objective is to develop a near real-time, non-destructive, AI-enabled system capable of screening pharmaceutical products and inputs through their packaging at ports of entry and other supply-chain nodes. By integrating multi-modal sensing, signal processing, and data fusion, the system aims to augment FDA oversight by detecting contamination, adulteration, and formulation variability without opening containers. The program is structured as a 54-month effort divided into three 18-month phases, culminating in a fieldable platform with integrated visual imaging and machine-readable code documentation. Eligible respondents include universities, non-profit organizations, small businesses, and other commercial entities, provided they maintain active registration in SAM.gov and are not entities of concern under the CHIPS and Science Act of 2022. The submission process requires a mandatory Solution Summary Presentation by September 21, 2026, followed by a full proposal due by November 10, 2026. Full proposals must include a technical and management plan, a task description document, a cost proposal narrative and workbook, and a milestone payment schedule. Selection will favor technologies capable of analyzing a broad range of products and packaging, while destructive testing methods and technologies requiring the opening of samples are explicitly excluded from the scope.