Technology InteGrator and AcceleratoR (TIGAR)
Contract Overview
Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.
AI Contract Overview
The Technology InteGrator and AcceleratoR (TIGAR) program, managed by the Advanced Research Projects Agency for Health (ARPA-H), is a solicitation for early-stage, high-risk, and high-impact biopreservation concepts. The effort seeks to develop enabling technologies—such as new materials, AI/ML, and innovative packaging—to achieve temperature-flexible storage for large and complex biological systems, including regenerative tissues and organs. The primary goal is to reduce reliance on strictly controlled temperature zones and remove logistical hurdles for distributing complex biologics, specifically targeting functional preservation of entire structures or one cubic centimeter volumes of tissue at practical temperatures using conventional equipment. The program is structured as multiple Other Transaction (OT) Agreements with a maximum funding request of 2 million USD per proposal over an 18-month period of performance. This period is divided into two 9-month phases, with a down-select decision occurring after Phase 1. Eligible applicants include small businesses, universities, non-profit organizations, and other commercial entities, provided they are registered in SAM.gov and possess a valid Unique Entity Identifier. Awards are prohibited for entities of concern under the CHIPS and Science Act of 2022 or those participating in malign foreign talent recruitment programs. The submission process involves two steps: a seven-minute solution video with captions and supplemental slides, followed by a full proposal consisting of technical, management, and cost volumes. For Intake Group 1, the solution video is due August 12, 2026, and the full proposal is due September 17, 2026. Proposals are evaluated based on overall scientific and technical merit, team expertise, potential impact on biomedicine, user focus, and cost realism. Key administrative requirements include the disclosure of organizational conflicts of interest and compliance with research security reviews for selected proposals.
General Info
Agency
Place of Performance
Washington, DC, USASet-Aside
Timeline
Response Deadline
Organization & Contact Information
Full Description
Amendment 4
The ISO was updated to extend the Solution Video submission deadline to August 12, 2026 and the Full Proposal submission deadline to September 17, 2026 for intake Group 1. See page 3 of the full text ISO for more information.
Amendment 3
(1) Appendix B was updated to remove track changes
(2) Appendix C4 was updated to remove an erroneous comment.
Amendment 2
(1) Instructions on how to submit a Solution Video were added to the ISO (see pages 7-8).
(2) Information related to the Video Captions file was added to Appendix B.0 (Solution Video Format and Instructions).
(3) The instructions in Appendix B.1 (Template for Supplemental Slides) were simplified, and a Cost Summary slide was added (see Slide 7).
(4) Appendix C.3 was updated to reference "Phase" rather than "Year" for clarity.
(5) The Administation and National Policy document in Appendix C.4 was replaced with an updated document.
Amendment 1
The ISO was updated with the new webinar and webinar registration dates.
Effort Description:
TIGAR Exploratory Topic will forge entirely new paths to stabilizing regenerative tissues and organs by seeding the development of enabling technologies that can unlock temperature-flexible storage in increasingly larger and more complex biological systems. Solutions may involve any combination of new materials, artificial intelligence/machine learning, high-throughput screening methods, biological interventions, devices, processing methods, analytical technology, and packaging approaches that can overcome current roadblocks and yield a leap in the ability to store and distribute complex biologics, without introducing high cost or complexity. Strategies that reduce reliance on strictly controlled temperature zones and can ensure safe storage in a range of environmental conditions are preferred. While long-term temperature-flexible storage is ideal, any advance that removes logistical hurdles or establishes shelf-life stability at easy to maintain temperatures (preferably non-cryogenic) will be considered. Innovations at the cellular level without a strategy for deployment in thick tissues will not be considered.
Please ensure to follow this opportunity for any updates.
For more information on the TIGAR Exploratory Topic visit: https://arpa-h.gov/explore-funding/initiatives-and-sprints/tigar
For information on Proposer's Day details and registration information, please see Special Notice ARPA-H-SN-26-142
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