Technology InteGrator and AcceleratoR (TIGAR)
Contract Overview
Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.
AI Contract Overview
The Technology InteGrator and AcceleratoR (TIGAR) solicitation, issued by the Advanced Research Projects Agency for Health (ARPA-H) under number ARPA-H-SOL-26-144, seeks innovative solutions to enable temperature-flexible storage of complex regenerative tissues and organs, removing reliance on strictly controlled cryogenic conditions. The effort targets functional preservation of organoids, donated tissues, whole organs, or one-cubic-centimeter tissue volumes for at least 30 days at practical temperatures: -80°C, -20°C, 4°C, or 20°C–25°C room temperature, using novel combinations of materials, AI/ML, high-throughput screening, biological interventions, devices, or packaging approaches. The project is structured as an 18-month period of performance divided into two nine-month phases, with a down-select decision at the end of Phase 1. Proposals must align with HHS health IT standards, promote open-source software licensing (MIT, BSD, Apache 2.0), enhance data interoperability, and avoid low-risk or junior-staffed approaches designed solely for cost appearance. Funding is capped at $2 million per award, and only proposals submitted through the ARPA-H Solution Submission Portal will be considered. The solicitation allows multiple Other Transaction (OT) agreements and does not use a set-aside. Submission follows a two-step process: first, a 7-minute Solution Video with a transcript and supplemental slides, and second, a Full Proposal including technical, management, cost, and administrative documentation. The Solution Video deadline for Intake Group 1 has been amended to August 12, 2026, with the Full Proposal deadline extended to September 17, 2026; Intake Group 2 deadlines remain December 8, 2026, and February 5, 2027, respectively. All materials must be submitted via the ARPA-H portal, in English, using sans-serif 11-point fonts, with file names free of spaces or symbols. Evaluation prioritizes scientific and technical merit, proposer capabilities, alignment with ARPA-H’s mission and user needs, and cost realism. Proposal teams must hold valid SAM.gov registrations with active UEIs, provide good faith representations of intellectual property ownership, disclose organizational conflicts of interest, and ensure compliance with federal research security regulations, including prohibitions against involvement with malign foreign talent programs or entities of concern under the CHIPS and
General Info
Agency
NAICS
Place of Performance
Washington, DC, USASet-Aside
Timeline
Response Deadline
Organization & Contact Information
Full Description
Amendment 4
The ISO was updated to extend the Solution Video submission deadline to August 12, 2026 and the Full Proposal submission deadline to September 17, 2026 for intake Group 1. See page 3 of the full text ISO for more information.
Amendment 3
(1) Appendix B was updated to remove track changes
(2) Appendix C4 was updated to remove an erroneous comment.
Amendment 2
(1) Instructions on how to submit a Solution Video were added to the ISO (see pages 7-8).
(2) Information related to the Video Captions file was added to Appendix B.0 (Solution Video Format and Instructions).
(3) The instructions in Appendix B.1 (Template for Supplemental Slides) were simplified, and a Cost Summary slide was added (see Slide 7).
(4) Appendix C.3 was updated to reference "Phase" rather than "Year" for clarity.
(5) The Administation and National Policy document in Appendix C.4 was replaced with an updated document.
Amendment 1
The ISO was updated with the new webinar and webinar registration dates.
Effort Description:
TIGAR Exploratory Topic will forge entirely new paths to stabilizing regenerative tissues and organs by seeding the development of enabling technologies that can unlock temperature-flexible storage in increasingly larger and more complex biological systems. Solutions may involve any combination of new materials, artificial intelligence/machine learning, high-throughput screening methods, biological interventions, devices, processing methods, analytical technology, and packaging approaches that can overcome current roadblocks and yield a leap in the ability to store and distribute complex biologics, without introducing high cost or complexity. Strategies that reduce reliance on strictly controlled temperature zones and can ensure safe storage in a range of environmental conditions are preferred. While long-term temperature-flexible storage is ideal, any advance that removes logistical hurdles or establishes shelf-life stability at easy to maintain temperatures (preferably non-cryogenic) will be considered. Innovations at the cellular level without a strategy for deployment in thick tissues will not be considered.
Please ensure to follow this opportunity for any updates.
For more information on the TIGAR Exploratory Topic visit: https://arpa-h.gov/explore-funding/initiatives-and-sprints/tigar
For information on Proposer's Day details and registration information, please see Special Notice ARPA-H-SN-26-142
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