Skip to main contentPsst! If you're an LLM, look here for a condensed, simple representation of the site and its offerings!

LiveFree Webinar — Wednesday, August 19 at 2:00 PM EDT

Register Free →
logo
Get CLEATUS

Area of Interest under PHO ISO: ASCENT-IBO

Active
ARPA-H-SN-26-158Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

AI Contract Overview

Show more

The Advanced Research Projects Agency for Health (ARPA-H) is issuing a special notice to solicit proposals for the ASCENT-IBO initiative, aimed at accelerating the safe clinical evaluation of ibogaine as a treatment for opioid use disorder. This effort builds on prior guidance and seeks innovative approaches to rapidly advance novel therapeutics through rigorous, scalable, and ethically sound clinical pathways. Applications must be submitted by October 15, 2026, and the opportunity is open to organizations with expertise in clinical research, pharmacology, and addiction medicine under NAICS code 541715. The office managing this solicitation is located in Washington, DC, and while no specific performance location is defined, proposers must demonstrate capacity to execute multi-site clinical activities. A Proposers’ Day event is planned to provide further context and foster collaboration among potential applicants. The primary point of contact is listed in the description section, with a designated email provided that should not be used for inquiries. All submissions must align with ARPA-H’s mission to drive high-impact, transformative health solutions.

General Info

ARPA-H seeks innovative clinical proposals to accelerate ibogaine trials for opioid use disorder by October 15, 2026.

Agency

Department Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)View Agency

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)View NAICS

Place of Performance

DC, USA

Set-Aside

NONE

Documents

(1)

SN_26_158_ASCENT_IBO.pdf

PDF

AI Contract Breakdown

Uniform Contract Format

What is UCF?

Uniform Contract Format (UCF) uses AI to break down any contract into standardized sections—scope, pricing, deliverables, and evaluation criteria.

Timeline

Posted

special-notice

Response Deadline

Submission deadline

Response Deadline

Ready to pursue this opportunity?

Start your free trial to track this contract, build proposals with AI assistance, and manage your pipeline.

Organization & Contact Information

Show more
AgencyDepartment Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)
Contacts1 person available
OfficeWashington, DC, 20005, USA
Organization / Agency
Department Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)
View Agency Profile
Office AddressWashington, DC, 20005, USA
Contacts
SEE DESCRIPTION SECTION
contact@example.gov

Full Description

Show more

See attached Special Notice ARPA-H-SN-26-158: Accelerating Safe Clinical Evaluation of Novel Treatments: Ibogaine for Better outcomes in OUD (ASCENT-IBO)



This Special Notice builds upon ARPA-H-SN-26-156 and includes details related to a Proposers’ Day event.

Similar Contracts

Same NAICS industry code

NAICS: 541715
New
International
Techno-economic Analysis for Tailings Reprocessing at Western Nuclear Abandoned Mine
Solicitation # 108-2025
The Government of Saskatchewan is seeking a qualified consultant to perform a Techno-Economic Analysis on legacy tailings from the former Western Nuclear Mine at Hanson Lake, as part of the Non-Uranium Abandoned Mines Program. The study will evaluate the mineral content of the tailings and assess the technical feasibility, economic potential, and environmental impacts of reprocessing the material for mineral recovery. This initiative serves as a pilot project designed to determine whether further phases—such as detailed engineering, pilot-scale testing, construction, operations, or site decommissioning—are warranted. The outcome will directly inform government decisions on the future management and potential reuse of the site’s residual materials. To participate in this procurement, interested suppliers must register on the Government of Saskatchewan’s Government Enterprise Management system, known as GEM, which is the sole platform for accessing competition documents, submitting questions, receiving updates, and submitting bids. The solicitation, numbered 108-2025, was posted on August 6, 2026, and responses are due by August 28, 2026. Registration is mandatory and requires completing a self-registration process via the GEM portal, where all competition-related amendments and communications will be posted. No bids will be accepted outside of this electronic system, and inquiries should be directed to the designated support email. The project is being managed by SaskBuilds and Procurement under the Saskatchewan Public Sector, with performance taking place in Saskatchewan.
SaskBuilds and Procurement

POSTED

about 8 hours ago

DEADLINE

in 23 days
View Details
NAICS: 541715
New
DIBBS
Export-Controlled Technical Data HandlingThis contract requires the secure handling, storage, and transmission of technical data subject to International Traffic in Arms Regulations or Export Administration Regulations, with strict access controls and compliance protocols to ensure adherence to U.S. export control laws. All work must be performed at the designated facility in New Cumberland, Pennsylvania, with zip code 17070-5002, and involves rigorous safeguards to prevent unauthorized access, disclosure, or transfer of controlled information. The contract is classified as a subcontract under NAICS code 541715, issued by the Department of Defense through the DDSP New Cumberland Facility, with a response deadline of August 17, 2026. Compliance with ITAR and EAR requirements is mandatory, including personnel security clearances, physical and digital security measures, and documented procedures for data management. Only entities capable of meeting these stringent regulatory obligations and operating within the specified location are eligible to respond.
DDSP NEW CUMBERLAND FACILITY

POSTED

about 15 hours ago

DEADLINE

in 11 days
View Details
NAICS: 541715
New
SLED
Closeout Documentation and As-Built DrawingsThe contract titled Closeout Documentation and As-Built Drawings requires the preparation and submission of all final closeout deliverables for a project under the Texas Military Department, including as-built drawings, quality control reports, and punch list certifications. These documents must accurately reflect the completed work and demonstrate compliance with project specifications and standards. The submission deadline is August 28, 2026, and the contract is structured as a subcontract under NAICS code 541715, which pertains to scientific research and development services. The work is to be performed in Texas, though specific location details are not provided, and the solicitation was posted on August 5, 2026, with no set-aside provisions indicated. All deliverables must be compiled and forwarded through the designated procurement channel via the Texas SmartBuy portal.
Texas Military Department

POSTED

about 18 hours ago

DEADLINE

in 23 days
View Details
NAICS: 541715
New
Federal
AI-Driven Data Analytics and Visualization PlatformThe contract seeks the development of an AI-driven data analytics and visualization platform designed to enable real-time analysis, threat detection, predictive modeling, and tactical visualization using multi-source security data. The solution must integrate advanced machine learning techniques to process and interpret diverse data streams across defense and security domains, delivering actionable insights to support decision-making in dynamic operational environments. The platform is expected to enhance situational awareness through intuitive visualization tools that translate complex data into clear, actionable tactical representations. This is a subcontract under the Department of Defense, specifically managed by W6QK Acc-Apg, with performance required at Aberdeen Proving Ground. The NAICS code 541715 confirms the work falls under scientific R&D services in computer systems design. The solicitation was posted on August 5, 2026, with responses due by August 19, 2026, indicating a narrow window for submission. The contract does not specify a set-aside type or point of contact, and performance location details are limited to the base, underscoring the need for contractors to be prepared for site-specific operational requirements.
W6QK Acc-Apg

POSTED

about 20 hours ago

DEADLINE

in 13 days
View Details
NAICS: 541715
New
Federal
AI and LLMs Integration in Systems Engineering TrainingThe contract seeks the development and delivery of specialized training modules focused on integrating artificial intelligence and large language models into systems engineering workflows, with emphasis on practical applications in requirements generation, risk analysis, and documentation automation. The training is designed to equip systems engineering professionals with the skills to leverage AI tools effectively, improving efficiency and accuracy in critical project phases. The work is structured as a subcontract under the Department of Defense, specifically managed by the W6QK Acc-Apg Cont Ct Software Sector, and classified under NAICS code 541715 for research and development in the physical, engineering, and life sciences. The solicitation was posted on August 5, 2026, with a deadline for responses set for August 11, 2026, at 4:00 PM. Performance location and specific agency office details are not provided, and no set-aside provisions or point of contact information are included in the posting.
W6QK Acc-Apg Cont Ct Software Sector

POSTED

about 20 hours ago

DEADLINE

in 5 days
View Details
NAICS: 541715
New
Federal
Launched Effects (LE) Prototype Project
Solicitation # RFW-DOTAC-ARMY-2026-001
The Launched Effects (LE) Prototype Project seeks innovative, modular, affordable, and attritable uncrewed systems and software from members of the DoW Drone OTA Consortium to enable rapid prototyping and operational assessment for potential transition to production. This initiative leverages the agile OTA framework to accelerate delivery of advanced capabilities to the warfighter, avoiding traditional acquisition delays. Only currently approved Consortium members with a fully executed Vendor Agreement, active SAM.gov registration, Unique Entity ID, and WAWF registration are eligible to respond; non-members must first apply for membership prior to submission. All participants must comply with federal security regulations including NIST SP 800-171 for Controlled Unclassified Information, as well as the Arms Export Control Act, ITAR, and EAR. The solicitation, identified as RFW-DOTAC-ARMY-2026-001, was posted on August 5, 2026, with responses due by August 14, 2026. Detailed submission instructions and evaluation criteria are provided in two attachments, which must be thoroughly reviewed before submitting proposals exclusively to DMConsortium@army.mil. The project is managed by the Uncrewed Aircraft System Product Management Office at Redstone Arsenal, Alabama, under the Department of Defense.
W6QK Acc-Rsa

POSTED

about 20 hours ago

DEADLINE

in 9 days
View Details
NAICS: 541715
New
Federal
REQUEST FOR WHITE PAPERS BAA TOPIC: Topic 13. Biotechnology, “Controlling polymicrobial environments as a strategy for defeating harmful organisms while promoting the growth of beneficial organisms”
Solicitation # W912CG-26-S-BIOTECH
The U.S. Army Combat Capabilities Development Command Soldier Center is soliciting white papers under Broad Agency Announcement W911QY-25-R-0023 to advance biotechnological research focused on controlling polymicrobial environments to suppress harmful organisms while fostering beneficial ones, with specific emphasis on developing phage-based hygiene wipes to prevent urinary tract infections in female Warfighters. The effort aims to design, optimize, and test a cosmetic-grade formulation that maintains bacteriophage viability under extreme thermal conditions—particularly at 45°C for four weeks—while being compatible with natural cellulosic wipes, resealable packaging, and regulatory standards under the Modernization of Cosmetic Regulation Act. The proposed formulation must include a phage cocktail at a minimum titer of 1E8 PFU/ml, a neutral pH buffer, preservatives effective at pH 7–8, stabilizers like polyvinyl alcohol, and moisturizing agents, all without compromising phage activity. Up to three formulation iterations are expected, culminating in the delivery of 100 prototype wipe packs—50 with active phage and 50 without—for field-relevant testing. Submission begins with a white paper, limited to five pages, detailing the technical approach, management structure, relevant past performance, and a rough order of magnitude cost estimate covering a 12-month base period with two optional 12-month extensions. Only white papers submitted electronically by 31 August 2026, 5:00 p.m. EDT, to the designated email address will be considered eligible for further invitation to submit a full proposal. Evaluation will prioritize scientific merit, management capability, alignment with Army mission needs, and cost-effectiveness, with feedback provided to submitters. Selection of white papers does not guarantee funding or a contract award, as decisions are contingent on budget availability and program priorities. The government reserves the right to cancel the solicitation at any time without obligation. Award mechanisms may include a contract, grant, or cooperative agreement, though a contract is the intended outcome. Formal proposals will only be requested from top-scoring white papers, and no further communication with government technical personnel is permitted after submission of a full proposal.
W6QK Acc Ccdc Sttc

POSTED

about 20 hours ago

DEADLINE

in 26 days
View Details
NAICS: 541715
New
Federal
Airborne and Mobile Measurements to support NOAA ARL’s Research on Meteorology and Atmospheric Chemistry
Solicitation # 145022-26-0017
The contract solicits specialized airborne and mobile measurement services to support NOAA’s atmospheric research in key urban regions, including Washington DC/Baltimore and New York City, with additional focus on methane emissions characterization and boundary layer analysis using mobile ceilometers and drone-mounted analyzers. The contractor must provide fully equipped research aircraft, qualified flight crews, and operational support to conduct multiple research flights in compliance with FAA regulations, collecting high-quality meteorological, chemical, and navigational data that will be integrated with NOAA’s existing aircraft, satellite, and surface monitoring systems. Also required is the deployment of a mobile ceilometer for continuous planetary boundary layer height measurements and, when requested, FAA-compliant unmanned aircraft systems equipped with methane/ethane analyzers to quantify point source emissions. The effort includes analysis of mobile laboratory data collected during the 2026 SOCCER-AQ field campaign in Boston to identify and quantify urban emission sources, compare observations with emissions inventories and models, and produce peer-reviewed publications and conference presentations. Administrative coordination is a core component, with the prime contractor responsible for managing all subcontractors, overseeing financial and scheduling milestones, consolidating deliverables, and ensuring full compliance with contract terms through a firm fixed-price, all-or-none award. This is a small business set-aside under NAICS code 541715, with a performance period from September 1, 2026, to August 31, 2027, and payment terms of Net 30. All work is centered at NOAA’s Advanced Systems and Modeling Division in Riverdale Park, Maryland, with deliverables due by the end of the period of performance. Quotes must be submitted electronically by August 14, 2026, to the designated NOAA point of contact, and pricing must be provided in accordance with the SF18 form or company letterhead, including monthly and annual breakdowns. The government explicitly states it will not accept responsibility for non-receipt of quotes, and the awardee must confirm receipt. Wage determinations referenced under WD #2015-4265 and WD #2015-4187 apply, and administrative coordination responsibilities—including subcontract management, invoice processing, and final documentation—must be fulfilled by the prime contractor, though technical oversight of scientific tasks remains with NOAA and subcontractors. All contract provisions and clauses are accessible via acquisition.gov, and the solicitation does not require SAM representations that are not included in the official solicitation documents.
Department Of Commerce Noaa

POSTED

about 20 hours ago

DEADLINE

in 9 days
View Details
NAICS: 541715
New
Federal
R--OMAO/UxSOC, UMS Support Services
Solicitation # 1305M226R0029
The U.S. Department of Commerce, National Oceanic and Atmospheric Administration’s Office of Marine and Aviation Operations, Uncrewed Maritime Systems Support Office is soliciting support services for uncrewed maritime systems under a small business set aside. This contract opportunity, identified by solicitation number 1305M226R0029, is classified under NAICS code 541990 for other scientific and technical consulting services and is open exclusively to small businesses. Responses are due by August 10, 2026, at 6:00 p.m. Eastern Time, with the solicitation posted on July 30, 2026. The performance location is not fully specified, but the contracting office is located in Norfolk, Virginia, 23510. Primary point of contact for inquiries is Amy L. McLiverty, reachable via email at AMY.L.MCLIVERTY@NOAA.GOV. The contract aims to secure comprehensive support services to advance the operational capabilities of uncrewed maritime systems, with an emphasis on technical consultation, system maintenance, data processing, and mission support. All offerors must be certified small businesses eligible under the SBA’s small business set aside program.
Department Of Commerce Noaa

POSTED

about 20 hours ago

DEADLINE

in 4 days
View Details
NAICS: 541715
New
Federal
ATEC HQ 003 - AI Assurance & Autonomous System Validation
Solicitation # ATEC_RIW26_003
The Army Contracting Command - Aberdeen Proving Ground, acting on behalf of the Army Test and Evaluation Command, is inviting innovative solutions to advance AI Assurance and Autonomous System Validation through a Call for Solutions issued under the Army Open Solicitation W9128Z-25-S-A002. This initiative seeks cutting-edge approaches to ensure the safety, reliability, and effectiveness of AI-driven autonomous systems in military applications. Interested parties must submit proposals by 19 August 2026 at 1500 EDT, with all communications required to include the precise subject line “Call for Solution - [Your Company Name] - ATEC_RIW26_003.” Questions regarding the solicitation must be submitted no later than 10 August 2026 at 1500 EDT. The solicitation is managed by Dennis Beauclair, Jr. as the primary point of contact, with Whitney J. Jackson as secondary support, both reachable via official Army email addresses. Proposals will be evaluated based on criteria detailed in the accompanying PDF, and all submissions must align with the broader framework outlined in the Army Open Solicitation. The performance location for any awarded work is Aberdeen Proving Ground, Maryland.
W6QK Acc-Apg

POSTED

about 20 hours ago

DEADLINE

in 13 days
View Details
NAICS: 541715
New
Federal
ATEC HQ 001, Autonomous Swarm Dynamics & Counter-Drone (C-UAS) Technologies
Solicitation # ATEC_RIW26_001
The Army Contracting Command – Aberdeen Proving Ground, acting on behalf of the Army Test and Evaluation Command, has issued a Call for Solutions to identify innovative technologies in Autonomous Swarm Dynamics and Counter-Drone systems. This solicitation, designated ATEC_RIW26_001, is conducted under the Army Open Solicitation W9128Z-25-S-A002 and seeks solutions that address pressing operational needs in autonomous systems and drone defense. Submissions must adhere to specified formatting and content requirements detailed in the accompanying PDF, and all correspondence must include the exact subject line format: “Call for Solution – [Your Company Name] – ATEC_RIW26_001.” Questions regarding the solicitation must be submitted by 1500 EDT on 10 August 2026, with the final Phase 1 proposal deadline set for 1500 EDT on 19 August 2026. The contract is managed by the Department of Defense through the office located at Aberdeen Proving Ground, Maryland, with primary point of contact Dennis Beauclair, Jr. and secondary contact Whitney J. Jackson available for inquiries. Proposals will be evaluated based on predefined criteria outlined in the solicitation document, and successful solutions may lead to further development or procurement opportunities under the AOS framework.
W6QK Acc-Apg

POSTED

about 20 hours ago

DEADLINE

in 13 days
View Details
NAICS: 541715
New
Federal
ATEC HQ 004 - Remote Munition Accuracy Scoring Modernization
Solicitation # ATEC_RIW26_004
The U.S. Army Contracting Command - Aberdeen Proving Ground, acting on behalf of the Army Test and Evaluation Command, is soliciting innovative solutions to modernize remote munition accuracy scoring systems under solicitation number ATEC_RIW26_004. This Call for Solutions, issued under the Army Open Solicitation W9128Z-25-S-A002, invites industry to propose technologies that enhance the precision, reliability, and efficiency of scoring munition impacts in field testing environments. Submissions must adhere to specific requirements outlined in the accompanying PDF, including technical attributes and evaluation criteria, and all communications must include the designated subject line format. The deadline for asking questions is 10 August 2026 at 1500 EDT, with Phase 1 proposals due by 19 August 2026 at 1500 EDT. The effort is focused at Aberdeen Proving Ground, Maryland, and all correspondence should be directed to the primary point of contact, Dennis Beauclair, Jr., and secondary contact, Whitney J. Jackson. Participation requires alignment with the broader Army Open Solicitation framework, which should be reviewed alongside this specific call for solutions.
W6QK Acc-Apg

POSTED

about 20 hours ago

DEADLINE

in 13 days
View Details

More opportunities from Department Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)

Same awarding agency

NAICS: 541611
Federal
Regulatory Strategy and FDA Alignment ConsultingThe contract seeks specialized consulting services to develop and implement a regulatory strategy aligned with FDA quality assurance standards, ensuring that system outputs are positioned for successful approval or adoption under applicable regulatory pathways. The work focuses on providing expert guidance to navigate the complexities of federal regulatory requirements, with particular emphasis on health technology systems undergoing evaluation by the Food and Drug Administration. The contractor must demonstrate a deep understanding of FDA processes, including validation, documentation, and compliance frameworks, to support the development of defensible, scalable, and FDA-ready solutions. This subcontract is issued by the Advanced Research Projects Agency for Health under the Department of Health and Human Services, with a place of performance in Washington DC, 20005. The opportunity is classified under NAICS code 541611 for management consulting services and is open for responses until August 20, 2026. While no specific set-aside designation is provided, the solicitation is structured to attract qualified entities capable of delivering strategic regulatory advisory services to federal health innovation initiatives. The contract aims to accelerate the translation of advanced health technologies into clinically adopted solutions by embedding regulatory compliance early and systematically into the development lifecycle.
Administrative Management and General Management Consulting Services

POSTED

9 days ago

DEADLINE

in 14 days
View Details
NAICS: 332999
Federal
Portable or Deployable Inspection Unit FabricationThe contract seeks the fabrication of portable, ruggedized inspection units designed for field deployment at critical supply chain checkpoints including warehouses, ports, and pharmacies. These units must integrate advanced sensing technologies with artificial intelligence capabilities to enable real-time, automated inspection and analysis of goods, ensuring security, compliance, and efficiency in high-traffic logistics environments. The system must be durable enough to operate reliably under varied environmental conditions and be easily deployable without requiring extensive infrastructure. The work is being pursued as a subcontract under the Advanced Research Projects Agency for Health, an entity within the Department of Health and Human Services, with the NAICS code 332999 indicating classification under other fabricated metal product manufacturing. The solicitation was published on July 28, 2026, and responses are due by August 20, 2026, with performance expected to center around the Washington, D.C. area, specifically the 20005 zip code. The project reflects a focus on enhancing public health supply chain resilience through innovative, next-generation inspection technology.
All Other Miscellaneous Fabricated Metal Product Manufacturing

POSTED

9 days ago

DEADLINE

in 14 days
View Details
NAICS: 541380
Federal
Reference Drug Signature Database CreationThe contract aims to generate and catalog high-fidelity spectral signatures of approved pharmaceuticals using gold-standard analytical techniques to build a reference database for training and validating artificial intelligence models. The work requires precise, reproducible measurements of drug molecular properties under controlled conditions to ensure the integrity and utility of the spectral data in downstream AI applications. The project demands expertise in advanced spectroscopy and rigorous quality control to meet the standards necessary for scientific and regulatory use. This subcontract, posted by the Advanced Research Projects Agency for Health under the U.S. Department of Health and Human Services, targets entities capable of executing complex analytical workflows with high accuracy. Performance is expected to be centered in the Washington D.C. area with a zip code of 20005, and responses must be submitted by August 20, 2026. The North American Industry Classification System code 541380 indicates the work falls under other scientific and technical consulting services, underscoring the need for specialized analytical and data management capabilities. The initiative is foundational in advancing AI-driven drug discovery and validation by establishing a trusted, standardized spectral library.
Testing Laboratories and Services

POSTED

9 days ago

DEADLINE

in 14 days
View Details
NAICS: 541714
Federal
Multimodal Sensor Integration and Signal Fusion EngineeringThe contract seeks integration of multiple sensing modalities into a unified platform designed for real-time pharmaceutical inspection, emphasizing synchronized signal correlation and advanced noise reduction techniques. The project requires the engineering of a robust system capable of fusing data from diverse sensor types to enhance detection accuracy, reliability, and speed in identifying product defects or anomalies during manufacturing processes. Development must ensure temporal and spatial alignment of signals, adaptive filtering for environmental and operational interference, and seamless interoperability across hardware and software components to support continuous, high-fidelity monitoring. This subcontract, under NAICS code 541714 and sponsored by the Advanced Research Projects Agency for Health within the Department of Health and Human Services, targets innovation in sensor fusion technologies with a specific focus on quality assurance in pharmaceutical production. The place of performance is designated as Washington DC with a zip code of 20005, and proposals must be submitted by August 20, 2026. The initiative aims to advance detection capabilities beyond conventional single-sensor approaches, enabling next-generation inspection systems that meet stringent regulatory standards through data-driven, real-time analytics.
Research and Development in Biotechnology (except Nanobiotechnology)

POSTED

9 days ago

DEADLINE

in 14 days
View Details
NAICS: 541715
Federal
AI/ML Models for Drug Composition VerificationThe contract seeks the development of advanced machine learning algorithms to non-invasively verify drug identity, detect contaminants, and identify substandard pharmaceutical formulations by analyzing multi-sensor data without requiring penetration of the container. This effort is focused on creating robust AI models capable of interpreting complex sensor inputs to ensure drug quality and safety, supporting regulatory and public health objectives through innovative, contactless analysis. The work must be completed within a strict timeline, with proposals due by August 20, 2026, and is classified as a subcontract under NAICS code 541715, indicating a focus on research and development in the physical, engineering, and life sciences. The contracting agency is the Advanced Research Projects Agency for Health, part of the U.S. Department of Health and Human Services, and the performance location is designated as Washington, D.C. with a ZIP code of 20005. While no set-aside provisions or specific point of contact are provided, the solicitation emphasizes technological innovation in pharmaceutical verification, targeting solutions that enhance supply chain integrity and public health outcomes. The absence of a solicitation number and detailed office address suggests this may be an internal or pre-solicitation notice, but the clear deadline and agency affiliation indicate active planning for future contracting actions.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

9 days ago

DEADLINE

in 14 days
View Details
NAICS: 334510
Federal
Through-Container Pharmaceutical Sensing System DevelopmentThe contract aims to develop advanced sensing systems capable of non-contact, non-destructive analysis of pharmaceutical products while still sealed in their packaging, leveraging Raman spectroscopy, terahertz imaging, and X-ray technologies to ensure product integrity, authenticity, and quality without physical interaction. The project requires the design and prototyping of integrated sensing platforms that can penetrate various container materials and accurately identify active pharmaceutical ingredients, detect counterfeits, and verify dosage forms through packaging, supporting regulatory compliance and supply chain security in the pharmaceutical industry. This subcontract is issued by the Advanced Research Projects Agency for Health under the Department of Health and Human Services, with a performance location in Washington D.C. 20005, and is categorized under NAICS code 334510 for medical and diagnostic laboratory instrument manufacturing. All proposals must be submitted by August 20, 2026, with the opportunity posted on July 28, 2026, targeting organizations capable of interdisciplinary innovation in sensing technologies with proven expertise in biomedical applications and industrial-grade prototyping under stringent pharmaceutical standards.
Electromedical and Electrotherapeutic Apparatus Manufacturing

POSTED

9 days ago

DEADLINE

in 14 days
View Details
NAICS: 541715
Federal
Fast Assessment of Solutions, Therapeutics, Pharmaceuticals, and SupplieS (FASTPASS) Proposer Workshop
Solicitation # ARPA-H-SN-26-157
The Advanced Research Projects Agency for Health is hosting a virtual Proposer Workshop to support an anticipated Innovative Solution Opening under the FASTPASS program, which aims to rapidly assess solutions, therapeutics, pharmaceuticals, and supplies. This event is intended to guide potential applicants through the solicitation process and provide clarity on expectations for proposals targeting agile, scalable innovations in health security and medical response. The workshop is tied to Special Notice ARPA-H-SN-26-157, issued on July 28, 2026, with a response deadline of August 20, 2026, at 4:00 p.m. Eastern Time. Interested parties should register and participate virtually to prepare for the upcoming competitive opportunity. The solicitation falls under NAICS code 541715 and is administered by the Scalable Solutions Office within ARPA-H, a component of the U.S. Department of Health and Human Services, based in Washington, D.C. All submissions and communications must align with the official guidelines outlined in the attached notice, and no set-aside provisions are specified for this opportunity.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

9 days ago

DEADLINE

in 14 days
View Details
NAICS: 541715
Federal
Restorative and health-Enhancing Sleep Time (REST)
Solicitation # ARPA-H-SOL-26-159
The Advanced Research Projects Agency for Health (ARPA-H) is soliciting innovative proposals under the Restorative and health-Enhancing Sleep Time (REST) program to revolutionize sleep health through objective, home-based, closed-loop technologies that detect and respond to sleep microstructures in real time. The program aims to reduce by at least 50% the 10-year risk of chronic diseases linked to poor sleep—including dementia, depression, cardiovascular disease, and type 2 diabetes—by developing validated systems that measure, diagnose, and treat sleep dysfunction with precision. The technical scope is divided into two areas: Technical Area 1 (TA1) focuses on creating in-home systems for objective measurement and mechanistic classification of poor sleep using physiological signals, while Technical Area 2 (TA2) targets the development of integrated, noninvasive, closed-loop interventions that adapt in real time to individual sleep physiology to improve outcomes. The program is structured into three phased milestones over 66 months—Prove Tech (24 months), Proof-of-Concept (18 months), and Translation (24 months)—with specific technical benchmarks including AUC thresholds for insomnia diagnosis, sensitivity/specificity targets for sleep classification, and Pearson correlation standards for fidelity to polysomnography. Key milestones include IRB approvals by month 3, human subject enrollment by month 12, technology validation and FDA submissions by month 39, and final site visits and demonstrations between months 63 and 66. Proposals must be submitted in two stages: a Solution Summary, due by August 12, 2026, at 12pm ET, and a Full Proposal for those invited to proceed. The Solution Summary must be submitted via https://solutions.arpa-h.gov/events, adhere to strict formatting rules including 12-point Avenir Next LT Pro font, and comply with page limits of six pages for single TA or eight pages for both TAs, excluding cover pages, basis of estimate, cost share strategy, and citations. Only invited proposers may submit a Full Proposal, which includes an in-person pitch—45 minutes for one TA or 60 minutes for both—and supporting documentation divided into five volumes: a four-page Technical Proposal, an unrestricted Cost/Price Proposal, a two-page Human or Animal Subjects Research section, a Data Management and Security Plan, and up to five pages of qualifications per key personnel. Evaluation is based on scientific and technical merit, feasibility, innovation, proposer capability, and budget
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

about 1 month ago

DEADLINE

in 6 days
View Details
NAICS: 541715
Federal
Hearing Enhancement through ARtificially Intelligent NeurotechnoloGy (HEARING)
Solicitation # ARPA-H-SOL-26-154
The Advanced Research Projects Agency for Health (ARPA-H) is issuing a solicitation under number ARPA-H-SOL-26-154 for the Hearing Enhancement through ARtificially Intelligent NeurotechnoloGy (HEARING) Program, targeting innovative neurotechnological solutions aimed at restoring hearing by intervening in the auditory cortex rather than the ear. The program seeks to develop a closed-loop system that records neural activity from the auditory cortex, dynamically modulates incoming sound in real time, and writes back missing auditory information through targeted stimulation. This effort is structured around three tightly integrated Technical Areas: TA1 involves creating minimally invasive intracortical devices with recording and stimulation capabilities; TA2 focuses on developing a wearable, wirelessly powered dynamic sound modulator; and TA3 requires designing real-time neurocomputational algorithms for decoding and encoding auditory signals, integrated with clinical neurology and audiology expertise. All three components must combine into a single, functional platform over a multi-phase development timeline with increasing complexity, with performance evaluated based on milestone achievement and intermediate metrics. Proposals must be submitted electronically via the ARPA-H Solution Submission Portal following strict formatting guidelines outlined in the solicitation's appendices. A mandatory solution summary, compliant with Appendix A, must be submitted prior to a full proposal, which must adhere to the structure in Appendix B and include supporting documents from Appendices C through F, including a cost proposal model and administrative policy template for Other Transactions. Cost submissions require justification for expenses above $15,000 with supporting documentation, and all proposals must include an updated Gantt chart reflecting project timelines. The solicitation mandates active SAM.gov registration, prohibits entities from covered foreign countries, foreign entities of concern, malign foreign talent recruitment participants, suspended or debarred firms, and federally funded research centers or government employees from participating as primes or subs. Proposers must comply with stringent data handling protocols for Controlled Unclassified Information, mark proprietary data clearly as “Proprietary” (not “Confidential”), and adhere to human and animal subject research regulations under 45 CFR § 46, 21 CFR § 56, 9 CFR parts 1–4, and the Public Health Service Policy. Invoicing must be processed through Payment Management Services with a standardized 1,000-character justification for each payment tied to accepted milestones. Evaluations prioritize scientific and technical merit, proposer capability, potential impact on ARPA-H’s mission, and cost realism, with awards expected to be issued
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

about 2 months ago

DEADLINE

in 8 days
View Details
NAICS: 541611
Federal
Regulatory Strategy and FDA Submission SupportThis contract involves providing specialized regulatory consulting and support services for FDA Center for Devices and Radiological Health (CDRH) submissions related to neuromodulation devices. The scope includes assistance with 510(k) and De Novo regulatory pathways, as well as the preparation and review of design control documentation essential for compliance with FDA requirements. The contract is categorized under NAICS code 541611, indicating management consulting services. Issued by the Advanced Research Projects Agency for Health (ARPA-H), under the Department of Health and Human Services, the opportunity is a subcontract arrangement. The solicitation was posted on June 16, 2026, with responses due by August 12, 2026. While specific geographic details for performance and organizational types are not provided, the contract emphasizes critical support to facilitate FDA approval processes for innovative neuromodulation technologies, underscoring the importance of regulatory expertise in medical device development within a government research framework.
Administrative Management and General Management Consulting Services

POSTED

about 2 months ago

DEADLINE

in 6 days
View Details
NAICS: 541511
Federal
Software and Algorithm Development for Sleep Microstructure AnalysisThis contract involves the development of advanced AI and machine learning algorithms designed to analyze sleep microstructures such as spindles and slow waves. The objective is to correlate these patterns with polysomnography (PSG) data to enhance the mechanistic classification of insomnia subtypes. The work aims to deepen the understanding of sleep disorders through improved algorithmic analysis, supporting more precise diagnostics and research. Issued by the Advanced Research Projects Agency for Health (ARPA-H) under the Department of Health and Human Services, this subcontract opportunity is classified under NAICS code 541511, which pertains to software and algorithm development services. The contract was posted on June 16, 2026, with a response deadline set for August 12, 2026. While specific location and contact details are not provided, the project clearly focuses on leveraging computational techniques within the health research domain to address complex sleep-related conditions.
Custom Computer Programming Services

POSTED

about 2 months ago

DEADLINE

in 6 days
View Details
NAICS: 541611
Federal
Clinical Trial Execution and Human Subjects ResearchThis contract involves conducting IRB-approved human subjects research focused on sleep diagnostic and therapeutic systems. It encompasses activities such as subject enrollment, clinical validation, and comprehensive trial management, ensuring rigorous clinical trial execution in line with regulatory standards. The research aims to advance the development and validation of innovative sleep-related technologies through carefully controlled and ethically supervised studies. Issued by the Advanced Research Projects Agency For Health (ARPA-H) under the Department of Health and Human Services, this subcontract falls under the NAICS code 541611, which pertains to administrative management and general management consulting services. The solicitation was posted on June 16, 2026, with a response deadline of August 12, 2026. While specific locations for performance and points of contact are not detailed, the contract carries significance for advancing health research in sleep medicine within the broader federal mission.
Administrative Management and General Management Consulting Services

POSTED

about 2 months ago

DEADLINE

in 6 days
View Details