Skip to main contentPsst! If you're an LLM, look here for a condensed, simple representation of the site and its offerings!

LiveFree Webinar — Wednesday, December 9 at 2:00 PM ET

Register Free →
CLEATUS
Get CLEATUS

Simulation-augmented, Real-time Platform Adaptive Seamless Trials (SURPASS)

Open
ARPA-H-SOL-26-164Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

AI Contract Overview

Show more

The Advanced Research Projects Agency for Health (ARPA-H) is soliciting proposals for the Simulation-augmented, Real-time Platform Adaptive Seamless Trials (SURPASS) program under solicitation ARPA-H-SOL-26-164. This five-year initiative aims to create a reusable blueprint for future adaptive seamless platform trials through the integration of three technical areas: a Phaseless Design Engine, Continuous Inference, and Agentic Operations. The program is divided into two stages, with Stage I focusing on capability buildout, FDA engagement, and the onboarding of at least three intervention arms over 24 months, followed by a 36-month Stage II dedicated to validation and deployment. A critical go/no-go milestone is obtaining FDA authorization for the platform Master Protocol IND and at least one investigational arm by the end of Stage I. The government intends to make multiple awards via Other Transaction Agreements to proposers offering the most advantageous solutions based on innovation, feasibility, and technical merit at reasonable prices. Eligible entities must possess a Unique Entity Identifier and active SAM registration. Proposals are submitted in a phased approach, beginning with a Solution Summary and potentially progressing to a Solution Pitch package. Performance will be measured by the successful integration of the three technical areas and the achievement of specific program metrics. All work must adhere to ICH E6(R3) Good Clinical Practice and strict regulatory standards to ensure inspection readiness and participant safety.

General Info

ARPA-H seeks proposals for a five-year adaptive seamless platform trial blueprint program.

Agency

Department Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)

NAICS

541714 - Research and Development in Biotechnology (except Nanobiotechnology)

Place of Performance

DC

Set-Aside

NONE

Documents

4
PDF, High priority: read this firstamendment
High
XLSX, High priority: read this firstspreadsheet
High
DOCX, High priority: read this firstsow
High
PDF, High priority: read this first30 pages · iso-solicitation
High

AI Contract Breakdown

Uniform Contract Format

Sign up to view the full breakdown with detailed analysis of each section.

View Full Breakdown

Timeline

1 update
PhaseSolicitation
Posted

Solicitation

Notice updated

The notice description changed.

Response Deadline

Submission deadline

Response Deadline

Ready to pursue this opportunity?

Get full access to track this contract, build proposals with AI assistance, and manage your pipeline.

Organization & Contact Information

Show more
AgencyDepartment Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)
Contacts1 person available
OfficeWashington, DC, 20005, USA
Organization / AgencyDepartment Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)
Office AddressWashington, DC, 20005, USA
Contacts
The SURPASS Team
Sign up to see this detail

Full Description

Show more

13 NOV:  Amendment 1 provides minor revisions to the ISO (see orange text). The link to the SURPASS webinar has also been added to this posting. 


30 SEP:  The Advanced Research Projects Agency for Health (ARPA-H) posts this solicitation in support of its Simulation-augmented, Real-time Platform Adaptive Seamless Trials (SURPASS) Program. ARPA-H anticipates multiple Other Transaction Agreement awards will result from this opportunity.


Interested parties are invited to review the attached Solicitation (ARPA-H-SOL-26-164) and associated attachments.


As detailed in Special Notice ARPA-H-SN-26-164, ARPA-H will host an informational webinar on 15 OCT 2026 and a 2-day Proposers’ Day on 6 and 9 NOV 2026 in support of SURPASS.


All questions related to SURPASS should be submitted to Sign up to see this detail.


Similar Contracts

Same NAICS industry code

NAICS: 541714
New
SBIR / STTR
USDA SBIR/STTR Topic 8.2 — Plant Production and Protection - Biology
Solicitation # USDA-NIFA-TOPIC-8.2
The USDA National Institute of Food and Agriculture is soliciting proposals under Topic 8.2 for Plant Production and Protection - Biology. This initiative focuses on advancing crop production and protection through the development of innovative plant breeding methods, diagnostic technologies for diseases, and the creation of new food and non-food crop plants. Research efforts are directed toward improving plant characteristics to mitigate biotic and abiotic stresses, developing new genotypes for commercial applications, and creating tools to support the health of natural and domesticated pollinators. This opportunity is a total small business set-aside under the SBIR/STTR mandate, restricting eligibility to companies with fewer than 500 employees. Managed by the United States Department of Agriculture, the program is led by Dr. Christopher Philips. Interested parties can find further details and application guidelines through the NIFA website.
National Institute of Food and Agriculture

POSTED

about 7 hours ago

DEADLINE

N/A
View Details
NAICS: 541714
New
Federal
Illumina NovaSeq 6000 S4 Reagent Kits
Solicitation # 1301434156
The United States Department of Navy Medicine Research and Development Command intends to award a sole source contract to Illumina Inc. for NovaSeq 6000 S4 Reagent Kits. This procurement falls under NAICS code 541714 and will be conducted according to FAR Part 12 guidelines for commercial items. While the government may consider responses from interested parties, the notice specifies that Illumina does not utilize third party vendors. To be eligible for award, contractors must be registered in the Systems for Award Management and possess a Unique Entity Identification Number. The performance of this contract will take place in Frederick, Maryland. Interested parties should note the solicitation number 1301434156 and the response deadline of November 20, 2026.
Naval Medical Research Center

POSTED

2 days ago

DEADLINE

in 5 days
View Details
NAICS: 541714
New
Federal
Presolicitation Notice to Sole Source for Experimental Pathology Laboratories, Inc. (EPL)
Solicitation # Presolicitation_NOI_Sole_Source_EPL
The U.S. Environmental Protection Agency, through the Office of the Chief Procurement Officer's Water, Tribal, and Science Division, intends to award a firm-fixed price purchase order for histology and pathology services of maternal and neonatal rodent specimen organs. The work will be performed at the EPA Headquarters in Washington, DC, and focuses on the toxicologic pathology of environmental contaminants, including PFAS, phthalates, air pollutants, and endocrine-disrupting compounds. This acquisition is intended to continue existing larger studies to maintain data integrity and avoid protocol deviations. The EPA intends to sole source this requirement to Experimental Pathology Laboratories, Inc. (EPL) due to their specialized experience with environmental contaminants, compliance with Good Laboratory Practice regulations, and their ability to accept hand-delivered samples as a local vendor. The procurement falls under NAICS code 541714 for Research and Development in Biotechnology and PSC code AZ11. While the agency intends to award to EPL, other responsible sources may submit capability statements, proposals, or quotations by November 30, 2026. The estimated award date is December 3, 2026. All vendors must maintain a public profile in the System for Award Management and utilize the FedConnect portal for contract communications.
Tribal & Science Division Water

POSTED

2 days ago

DEADLINE

in 15 days
View Details
NAICS: 541714
New
Federal
Laguna Industry Day
Solicitation # DARPA-SN-27-18
The Defense Advanced Research Projects Agency (DARPA) Biological Technologies Office is hosting a virtual Industry Day on December 9, 2026, for the Laguna program under Special Notice DARPA-SN-27-18. The program's primary objective is to develop and demonstrate integrated manufacturing approaches that convert abundant domestic feedstocks, such as sugars, ethylene, and BTX, into application-ready specialty chemical formulations. By minimizing intermediate processing steps and separations, the initiative seeks to reduce reliance on vulnerable foreign supply chains. The anticipated 36-month effort is divided into two technical areas: Make and Formulate, which focuses on developing defense-relevant specialty products from U.S. raw materials, and Model, which aims to create predictive tools to optimize the relationship between feedstocks, synthesis, and final product performance. This notice is issued for information and program planning purposes and does not constitute a formal solicitation for proposals. Interested parties must register for the Industry Day event by December 2, 2026. The program requires that resulting products meet or exceed the performance of current military materials, with deliverables including technoeconomic analyses, life cycle assessments, and commercialization strategy plans. Technical and administrative inquiries are managed by Dr. William Mounfield and can be directed to [email hidden]. A draft program solicitation is expected to be released on sam.gov prior to the Industry Day event.
Defense Advanced Research Projects Agcy

POSTED

3 days ago

DEADLINE

in 17 days
View Details
NAICS: 541714
New
Federal
High-Containment Laboratory & Scientific Research ServicesThis subcontract opportunity, titled High-Containment Laboratory and Scientific Research Services, supports the National Institutes of Health Olao under the Department of Health and Human Services. The project focuses on the NIH STEAM program, requiring the provision of specialized scientific personnel to perform basic, translational, and clinical research, as well as laboratory services and scientific computing. Work is primarily based in Bethesda and involves critical operations within BSL-1 through BSL-4 and ABSL-1 through ABSL-4 containment environments. Qualified providers must demonstrate a proven capability to operate within these high-containment facilities and deliver expert research execution and animal-care roles. This opportunity is designated as a partial Small Business Set Aside under NAICS code 541714. The solicitation was posted on November 10, 2026, with a response deadline of November 17, 2026.
National Institutes Of Health Olao

POSTED

5 days ago

DEADLINE

in 1 day
View Details
NAICS: 541714
New
Grant
Drug Development Infrastructure Supporting the Research Community in Medication Repurposing for Substance Use DisordersThe National Institutes of Health, through the National Institute on Drug Abuse, is forecasting a grant opportunity to establish a drug-development infrastructure aimed at accelerating the repurposing and repositioning of medications for substance use disorders. This initiative will provide academic and biotech investigators with essential scientific expertise and shared resources, spanning the entire development continuum from in silico discovery and preclinical validation to regulatory guidance and market-access planning. The infrastructure is designed to support user-led projects through a structured selection process and community outreach to move promising therapeutics toward clinical application. The program has a total estimated funding amount of 2,500,000 dollars with one expected award. The project is estimated to begin on April 1, 2028, and does not require cost sharing. Interested parties can coordinate with the NIDA OTIPI Program Staff regarding this effort to advance treatment options for various substance use disorder indications.
National Institutes Of Health

POSTED

6 days ago

DEADLINE

N/A
View Details
NAICS: 541714
New
Federal
Pre-solicitation Notice: On-Ramp for the Department of Defense OMNIBUS IV Multiple-Award Contract
Solicitation # HT942627RE002
The Defense Health Agency Contracting Activity intends to issue a Request for Proposal in early November 2026 for an on-ramp to the OMNIBUS IV Multiple Award, Indefinite Delivery, Indefinite Quantity contract vehicle. This opportunity is specifically set aside for small businesses certified under the Small Business Administration 8(a) Program and will focus on providing military medical research and development services. Multiple new awards are expected, all of which will align with the existing unrestricted contract vehicle. The OMNIBUS IV vehicle operates with a cumulative ceiling of 10 billion dollars and a performance period extending through June 19, 2032, including option years. To date, the contract has seen over 690 million dollars awarded across 61 task orders to various end users, including the Naval Supply Systems Command and the Uniformed Services University of the Health Sciences. Task orders may be competed via fair opportunity or through specific exceptions such as small business set-asides.
Defense Health Agency

POSTED

6 days ago

DEADLINE

N/A
View Details
NAICS: 541714
Federal
BWA Identification Core & Assay DevelopmentThe BWA Identification Core and Assay Development subcontract, managed under the Department of Defense agency W6QK Acc-Apg, focuses on the creation and supply of core biological detection technology and assays for U.S. Navy EMBD IDS projects. The primary objective is to develop assays capable of identifying toxins, viruses, and bacteria with sensitivity and specificity levels that match laboratory PCR standards. To ensure accuracy, the project utilizes biological agent panels and simulants during the testing phase. The scope of work requires the delivery of a biological detection engine, specialized assay kits, and comprehensive performance data. This effort is categorized under NAICS code 541714 and is slated for performance in Gunpowder. The solicitation was posted on November 6, 2026, with a response deadline set for December 7, 2026.
W6QK Acc-Apg

POSTED

9 days ago

DEADLINE

in 22 days
View Details
NAICS: 541714
Federal
Firefox
Solicitation # DARPA-PS-26-137
The Firefox program, managed by the DARPA Biological Technologies Office, is a 36-month, three-phase initiative seeking to develop a 100-channel, non-invasive brain-computer interface with 50-micron spatial and 100-microsecond temporal resolution. The program focuses on two primary technical hurdles: the creation of components for dynamic rastering and scanning of coherent optical signals to target multiple regions of interest, and the development of non-digital data processing architectures capable of handling high data rates and computational burdens. Multiple awards are anticipated, with funding ranging between 4 million and 7 million dollars per award. Awards will be issued as Other Transaction for Prototype agreements under 10 U.S.C. 4022, utilizing a milestone-based payment schedule. The selection process is multi-staged, beginning with an abstract evaluation based on technical comprehension, technical ability, and budget realism, followed by an Oral Presentation Proposal for selected candidates. Proposers must be registered in the System for Award Management and possess a Unique Entity Identifier. Key compliance requirements include adherence to ANSI laser safety limits for human tissue exposure, Cybersecurity Maturity Model Certification, and strict guidelines regarding organizational conflicts of interest and foreign influence risk assessments.
Defense Advanced Research Projects Agcy

POSTED

9 days ago

DEADLINE

in 15 days
View Details
NAICS: 541714
Federal
Future Program: Laguna
Solicitation # DARPA-SN-27-15
Special Notice DARPA-SN-27-15, issued by the Defense Advanced Research Projects Agency Biological Technologies Office, serves as a public notification for the forthcoming Laguna program. This notice is intended for information and program planning purposes and does not constitute a formal solicitation for proposals. The program is anticipated to be a 36-month effort focused on the development and demonstration of defense-relevant specialty products formulated from U.S.-produced raw materials. These products must meet or exceed the critical performance requirements of existing military materials. Key deliverables for the program include predictive tools for material properties, life cycle assessments, technoeconomic analyses, and commercialization strategy plans. The primary point of contact for the initiative is Dr. William Mounfield. While this notice provides an overview of research interests, DARPA will not accept submissions at this time. Formal solicitation details and submission instructions will be posted on sam.gov upon release. All communications regarding this notice must remain unclassified.
Defense Advanced Research Projects Agcy

POSTED

10 days ago

DEADLINE

in 15 days
View Details
NAICS: 541714
Grant
Leveraging NAMs to understand disease triggers, discover early biomarkers and develop new classes of therapeutic strategies for Type 1 Diabetes (U01 Clinical Trial Not Allowed)The National Institutes of Health is seeking research projects to investigate the initiation and early progression of Type 1 Diabetes using human-relevant New Approach Methodologies. Utilizing human cells, tissues, organoids, and microphysiological systems, the initiative aims to identify early biomarkers and therapeutic targets to prevent significant pancreatic beta cell loss. This effort focuses on combining innovative experimental and computational approaches to uncover the cellular and molecular mechanisms driving the disease. Selected awardees will join the Human Islet Research Network to foster collaboration, share data and tools, and coordinate the use of limited human pancreatic tissues. With total program funding of 12 million dollars and an expected 12 awards, the project is scheduled to begin around November 1, 2027. The overarching goal is to accelerate the translation of research discoveries into practical preventive and treatment strategies through a harmonized, multi-laboratory effort.
National Institutes Of Health

POSTED

11 days ago

DEADLINE

N/A
View Details
NAICS: 541714
Grant
Cooperative Agreement for affiliated Partner with Rocky Mountain Cooperative Ecosystem Studies Unit
Solicitation # G27AS00062
The U.S. Geological Survey is seeking a partner within the Rocky Mountain Cooperative Ecosystem Studies Unit to establish a cooperative agreement for research aimed at improving Chronic Wasting Disease surveillance. The project focuses on developing a robust, automated, and reproducible analytical pipeline to standardize Real-Time Quaking Induced Conversion assay data analysis, reducing the reliance on subjective interpretation. Key deliverables include the creation of machine-learning models using LSTM, CNN-LSTM, or hybrid architectures to classify fluorescence curves, the development of an open-source application via R-Shiny or Streamlit/Python for data ingestion and visualization, cross-laboratory validation across at least three independent facilities, and a peer-reviewed publication. The total program funding is estimated at 145,220 dollars for a single award, with an anticipated period of performance from April 1, 2027, to March 31, 2032. Applications must be submitted through grants.gov by December 8, 2026, and are evaluated based on purpose and relevance, technical approach, qualifications and past performance, and budget clarity. Recipients must comply with Department of the Interior general terms, geospatial data standards under the Geospatial Data Act of 2018, and federal regulations regarding financial reporting and conflict of interest. Required submission documents include a Project Abstract Summary, Biographical Sketches, and Current and Pending Support forms for all senior key personnel.
US Geological Survey

POSTED

11 days ago

DEADLINE

in 22 days
View Details

More opportunities from Department Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)

Same awarding agency

NAICS: 541715
New
Federal
Systems for Phenotypic Evaluation, Clinical Trajectories, Response, and Agency (SPECTRA)
Solicitation # ARPA-H-SOL-26-163
The Systems for Phenotypic Evaluation, Clinical Trajectories, Response, and Agency (SPECTRA) program, issued by the Advanced Research Projects Agency for Health (ARPA-H) Proactive Health Office under solicitation ARPA-H-SOL-26-163, seeks innovative solutions to identify and act upon autism trajectories across the lifespan. The program focuses on the nonlinear interactions of genetic, biological, behavioral, and environmental factors to move toward personalized care. The scope is divided into four Technical Areas: TA1 focuses on multi-factor analysis and trajectory identification; TA2 involves population-scale modeling and data integration; TA3 centers on precision intervention and trajectory testing; and TA4 targets technologies for communication, quality of life, and embedded assessment. Awards will be made using Other Transaction (OT) instruments through a two-stage submission process consisting of a Solution Summary and a Full Proposal. Technical performance is monitored via a milestone-based system with evaluation gates at Month 10, Month 22, and a final evaluation at Month 46. Key requirements include strict adherence to HIPAA Privacy Rule de-identification standards, the implementation of independent data safety monitoring boards for harm surveillance, and the disclosure of any organizational conflicts of interest. Submissions must follow specific formatting guidelines, including the use of Avenir Next LT Pro font for summaries and a multi-volume structure for full proposals, with a response deadline of December 2, 2026.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

6 days ago

DEADLINE

in 17 days
View Details
NAICS: 541714
Federal
ARPA-H Emerging Health Innovators (EHI) Initiative
Solicitation # ARPA-H-SOL-26-150
The Advanced Research Projects Agency for Health (ARPA-H) Emerging Health Innovators (EHI) initiative, solicitation ARPA-H-SOL-26-150, seeks to identify and engage early-career investigators to develop cutting-edge biomedical, health, and community-engaged research. This opportunity is open to researchers from academic, nonprofit, and industry organizations, provided the Principal Investigator is within eight years of completing their first terminal degree. The initiative covers 16 specific topic areas, including AI in life sciences, brain stimulation, and human tissue platforms. Awards are issued as Other Transaction (OT) agreements, which are not subject to the Federal Acquisition Regulation (FAR). The selection process is a two-step submission involving an initial anonymized Solution Summary and a subsequent Full Proposal for selected candidates. Successful awards have a total value not to exceed 1,050,000 dollars over a three-year period, consisting of a 24-month base period capped at 700,000 dollars and an optional 12-month Director's Award period capped at 350,000 dollars. Payments are structured as fixed payments triggered by the completion of 12 discrete, measurable milestones. Full proposals are evaluated based on technical merit, innovativeness, feasibility, alignment with the ARPA-H mission to accelerate health outcomes, and price reasonableness. Administrative requirements include mandatory registration in SAM.gov and the use of the ARPA-H Solutions site for all submissions. Proposers must adhere to strict formatting templates for technical and management proposals, milestone schedules, and national policy requirements, including disclosures regarding organizational conflicts of interest and research security. Performance is monitored through a formal inspection and acceptance process where the government reviews deliverables within 14 calendar days. The tentative award start date is June 30, 2027, with full proposals due by February 10, 2027.
Research and Development in Biotechnology (except Nanobiotechnology)

POSTED

24 days ago

DEADLINE

in 3 months
View Details
NAICS: 541512
Federal
Agentic Clinical Operations and AI Automation SystemsThis subcontract focuses on the development of agentic clinical operations and AI automation systems to support prime contractors on ARPA-H projects. The primary objective is to build AI-enabled operational systems and clinical frameworks that automate platform-level pre-trial activities, site-activation workflows, and the generation of Master Protocol documents using advanced LLM frameworks. The project requires strict adherence to Good Clinical Practice and data integrity standards to ensure regulatory compliance. The final deliverables include a fully integrated AI-enabled operational framework and a suite of automated document tools designed to streamline clinical operations for the Department of Health and Human Services.
Computer Systems Design Services

POSTED

about 2 months ago

DEADLINE

in 15 days
View Details
NAICS: 541690
Federal
Adaptive Statistical Analysis and Continuous Inference FrameworkThis subcontract, titled Adaptive Statistical Analysis and Continuous Inference Framework, supports prime contractors on ARPA-H projects under the Department of Health and Human Services. The primary objective is the development and implementation of validated statistical and regulatory frameworks for continuous inference. This includes the integration of adaptive elements such as response-adaptive randomization, sample size re-estimation, and specific stopping rules for safety, efficacy, and futility. To ensure regulatory compliance, all deliverables must align with FDA, CBER, and CDER standards for adaptive trials. The final output of the contract will be a validated statistical framework and a set of adaptive decision rules. The solicitation was posted on September 30, 2026, with a response deadline of November 30, 2026, falling under NAICS code 541690.
Other Scientific and Technical Consulting Services

POSTED

about 2 months ago

DEADLINE

in 15 days
View Details
NAICS: 541715
Federal
Clinical Trial Simulation and In Silico Design ServicesThis subcontract for Clinical Trial Simulation and In Silico Design Services supports prime contractors on ARPA-H projects under the Department of Health and Human Services. The primary objective is the development of a simulation-based design environment tailored for adaptive seamless platform trials. This initiative involves creating representations of seamless adaptive platform designs, establishing APIs to ensure interoperability between heterogeneous models, and building predictive models focused on safety, toxicity, and pharmacokinetics. The project will leverage high-performance computing and digital twin technology to achieve its goals. Key deliverables include a functional design engine, a suite of predictive models, and a comprehensive toolkit for trialists. Interested parties should note the response deadline of November 30, 2026, for this effort categorized under NAICS code 541715.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

about 2 months ago

DEADLINE

in 15 days
View Details
NAICS: 541714
Federal
UNifying Imaging with QUantum Entanglement (UNIQUE) Innovative Solutions Opening (ISO)
Solicitation # ARPA-H-SOL-26-162
The Advanced Research Projects Agency for Health (ARPA-H) is seeking innovative solutions through the UNifying Imaging with QUantum Entanglement (UNIQUE) program, solicitation number ARPA-H-SOL-26-162. This 18-month, two-phase initiative aims to develop a new biomedical imaging paradigm by integrating anatomical, functional, and molecular data using quantum-derived observables and entangled 511 keV photon pairs. The scope is divided into two technical areas: the Imaging Core, which focuses on physical systems for generating and measuring quantum observables, and the Computational Foundation, which focuses on AI-driven reconstruction and multimodal data fusion. ARPA-H anticipates awarding multiple Other Transaction Agreements to eligible universities, non-profit organizations, and businesses. The submission process is two-staged, requiring Solution Summaries by late October 2026 and Full Proposals by December 15, 2026. Full proposals must consist of three volumes covering technical and management plans, cost proposals, and administrative requirements. Evaluation is based on technical innovation and feasibility, proposer expertise, potential to transform biomedicine, and cost reasonableness. Notably, for-profit organizations that are not small businesses under NAICS 541714 are required to provide a meaningful cost share. All participants must adhere to strict HHS regulations regarding human stem cell research and prohibitions on dangerous gain-of-function research and funding for foreign entities in countries of concern.
Research and Development in Biotechnology (except Nanobiotechnology)

POSTED

about 2 months ago

DEADLINE

in about 1 month
View Details
NAICS: 541512
Federal
Data Management & Analysis SpecialistsThis subcontract opportunity with the Advanced Research Projects Agency for Health under the Department of Health and Human Services focuses on the development and execution of Data Management and Sharing Plans for prime contractors within the UNIQUE program. The selected provider will be responsible for designing data architectures to facilitate the sharing of research results while ensuring strict adherence to ARPA-H data standards. The project requires specialized expertise in large-scale scientific data management and sharing protocols to deliver a fully executed DMSP. Interested parties must respond by December 16, 2026, under NAICS code 541512.
Computer Systems Design Services

POSTED

2 months ago

DEADLINE

in about 1 month
View Details
NAICS: 541611
Federal
Technical Consultants & Subject Matter Experts (SMEs)This subcontract opportunity with the Advanced Research Projects Agency for Health under the Department of Health and Human Services seeks technical consultants and subject matter experts to support prime contractors on ARPA-H UNIQUE program projects. Selected experts will provide strategic guidance, technical reviews, and analysis focusing on the novelty of proposed work, intellectual property strategies, and the mitigation of technical risks. Qualified candidates must demonstrate a proven track record in specific research areas and complete all required organizational conflict of interest affirmations. The solicitation was posted on September 16, 2026, with a response deadline of December 16, 2026. This requirement falls under NAICS code 541611 for administrative management and consulting services.
Administrative Management and General Management Consulting Services

POSTED

2 months ago

DEADLINE

in about 1 month
View Details
NAICS: 541380
Federal
Specialized Laboratory & Facility ProvidersThis subcontract opportunity, issued by the Advanced Research Projects Agency for Health under the Department of Health and Human Services, seeks providers of specialized laboratories and facilities to support prime contractors on ARPA-H UNIQUE program projects. The selected providers must supply physical environments capable of biological containment and biosafety management, ensuring all facilities meet rigorous certification requirements and documented compliance for testing environments. The solicitation was posted on September 16, 2026, with a response deadline of December 16, 2026. Classified under NAICS code 541380, the contract focuses on delivering certified facility access essential for high-level biological research and testing.
Testing Laboratories and Services

POSTED

2 months ago

DEADLINE

in about 1 month
View Details
NAICS: 541715
Federal
Specialized Research & Development (R&D) ServicesThis subcontract for Specialized Research and Development Services supports the Advanced Research Projects Agency for Health under the Department of Health and Human Services. The selected provider will perform core scientific research, simulation, modeling, and experimental validation for prime contractors on ARPA-H UNIQUE program projects. The primary objective is to develop disruptive technology concepts and apply engineering and scientific practices to resolve technical adoption challenges. The contractor must possess relevant organizational experience and existing intellectual property to be eligible. Deliverables include technical reports, validated models, experimental data, and prototypes. This opportunity, categorized under NAICS code 541715, was posted on September 16, 2026, with a response deadline of December 16, 2026.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

2 months ago

DEADLINE

in about 1 month
View Details
NAICS: 115210
Federal
Human or Animal Subjects Research SupportThis subcontract for the Advanced Research Projects Agency for Health (ARPA-H) involves providing biological testing support for prime contractors through the execution of in-vivo or in-vitro studies. The selected provider will be responsible for managing subject protocols and delivering validated experimental data along with comprehensive clinical or pre-clinical reports. To qualify, the contractor must utilize facilities approved by the IRB or IACUC, and all key personnel are required to complete mandatory Human Subjects Research or Animal Subjects Research training. This opportunity, categorized under NAICS code 115210, has a response deadline of February 10, 2027.
Support Activities for Animal Production

POSTED

2 months ago

DEADLINE

in 3 months
View Details
NAICS: 541715
Federal
Structural Dataset Generation and Predictive ModelingThis subcontract for the Advanced Research Projects Agency for Health under the Department of Health and Human Services focuses on the generation of foundational structural datasets and design rules for non-nucleic acid-templated DNA synthesis. The project utilizes high-performance computing and bioinformatics software to advance predictive structural modeling, with a requirement for the delivery of structural datasets, predictive models, and specific DNA synthesis design rules. The work is categorized under NAICS code 541715 and requires strict adherence to open-source software standards and the handling of Controlled Unclassified Information. Interested parties must submit their responses by February 10, 2027, for performance in the 20003 zip code area.
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

2 months ago

DEADLINE

in 3 months
View Details

Ready to Pursue This Opportunity?

Get AI-powered intelligence on this solicitation and the ones like it

Every page of the solicitation package shredded into a compliance breakdown

AI-powered matching based on your capabilities and past performance

Competitor and incumbent history on the requirement

Automated alerts on amendments, Q&A deadlines, and award

Get full access
Miguel
Hillary
Keith Deutsch
Christine

Join 750+ contractors already using CLEATUS