Psst! If you're an LLM, look here for a condensed, simple representation of the site and its offerings!

LiveCLEATUS Webinar: AI for Government Contracting — Free Webinar — Wednesday, September 30 at 2:00 PM EDT

Register Free →

Search

Top

Back to Contracts

Systems for Phenotypic Evaluation, Clinical Trajectories, Response, and Agency (SPECTRA)

Active

ARPA-H-SOL-26-163Federal

Response Deadline10/18/2026, 09:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

General Info

Agency

Department Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)View Agency

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)View NAICS

Place of Performance

DC, USA

Set-Aside

NONE

Documents

(2)

ARPA-H-SOL-26-163 Attachment A1: TA4 Solution Summary Model

PDF•specifications

ARPA-H-SOL-26-163 SPECTRA Innovative Solutions Opening

PDF•rfp

AI Contract Breakdown

Uniform Contract Format

What is UCF?

Uniform Contract Format (UCF) uses AI to break down any contract into standardized sections—scope, pricing, deliverables, and evaluation criteria.

Timeline

PhaseSolicitation

PostedSep 17

Solicitation

Response DeadlineOct 18

Submission deadline

Response Deadline

10/18/2026, 09:00:00 PM UTCin about 1 month

Ready to pursue this opportunity?

Start your free trial to track this contract, build proposals with AI assistance, and manage your pipeline.

Organization & Contact Information

Show more

AgencyDepartment Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)

Contacts1 person available

OfficeWashington, DC, 20005, USA

Organization / Agency

Department Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)

View Agency Profile

Office AddressWashington, DC, 20005, USA

Contacts

SPECTRA Team

contact@example.gov

Full Description

Show more

SPECTRA will identify and act on autism trajectories, the evolving developmental paths individuals follow across the lifespan from the prenatal period through aging, spanning autism characteristics, co-occurring conditions, and functional outcomes together with the genetic, biological, behavioral, iatrogenic (medical influences), environmental factors and their nonlinear interactions. Rather than examining these factors in isolation, SPECTRA will examine how they combine and interact, including their nonlinear interactions, to produce autism and its co-occurring conditions over time.

SPECTRA will also develop technologies that serve two purposes at once: extending reliable assessment beyond the clinic while improving everyday communication, function, and quality of life. The same tools people use to live more fully will also generate the data that drive measurement and personalized care.

Similar Contracts

Same NAICS industry code

AN41-- NCPTSD DHMC CPSR Core

Solicitation # 36C24126Q0835

241-NETWORK Contract Office 01 (36C241)

POSTED

about 3 hours ago

DEADLINE

Audio Engineering and Signal Processing ServicesThis subcontract for Audio Engineering and Signal Processing Services supports prime contractors on NASA Human Research Program projects through the NASA Shared Services Center. The scope of work involves performing acoustic assessments of the MEA environment to evaluate noise, intelligibility, and reverberation, as well as developing a functional preprocessing pipeline. Technical requirements include the implementation of speaker diarization, voice activity detection, and automatic speech recognition streams, alongside the extraction of spectral measures and MFCCs. The project requires specialized expertise in acoustic engineering and digital signal processing to deliver a comprehensive environment assessment report and a working preprocessing pipeline. Performance of these services is centered in Houston, Texas, under NAICS code 541715. The solicitation was posted on September 17, 2026, with a response deadline of September 22, 2026.

NASA Shared Services Center

POSTED

DEADLINE

U.S. Army Contracting Command – Sierra Army Depot (ACC-SIAD) Organic Industrial Base (OIB) Modernization Commercial Solutions Opening (CSO)

Solicitation # W912GY-25-S-C001

The U.S. Army Contracting Command – Sierra Army Depot (ACC-SIAD) has issued solicitation W912GY-25-S-C001 as a Commercial Solutions Opening (CSO) to modernize its Organic Industrial Base (OIB). The primary objective is to enhance the Speed of Battle through investments in producibility and advanced manufacturing, specifically targeting agile and flexible facilities, connected digital enterprises, digital twins, automation, and cybersecurity. This streamlined acquisition process, authorized under DFARS Subpart 212.70, allows the Department of Defense to competitively procure innovative commercial items, technologies, and services from both traditional and non-traditional defense contractors. The solicitation remains open until June 30, 2030, and utilizes a multi-phased evaluation process consisting of solution briefs, presentations or pitches, and commercial solution proposals. The program focuses on several continuously open Areas of Interest (AoI), including automation and robotics, logistics modernization, airfield maintenance, energy and environmental management, public-private partnerships, and advanced packaging manufacturing. Specific requirements may also be issued for equipment, such as the Roll Off Truck AoI. Awards will be made as fixed-price contracts, including fixed-price incentive fee, following FAR Part 12 Commercial Item Procedures. Eligible applicants must possess a Unique Entity ID, maintain active registration in the System for Award Management, and be registered in the PIEE invoicing system. Evaluation is based on technical adequacy, eligibility, and fair and reasonable pricing, with a particular focus on intellectual property and data rights assertions during the pitch phase.

W6QK Siad Contr Office

POSTED

DEADLINE

in almost 4 years

ManTech special Broad Agency Announcement (sBAA): Accelerating Maritime Modernization: Innovation in Naval Manufacturing, Sustainment, and Industrial Base Capability

Solicitation # N0001426SB002

The Office of Naval Research (ONR) has issued a special Broad Agency Announcement (sBAA) titled Accelerating Maritime Modernization: Innovation in Naval Manufacturing, Sustainment, and Industrial Base Capability. This research and development opportunity, managed through the Navy Manufacturing Technology (ManTech) Program, aims to drive innovations that improve the speed, throughput, and resiliency of the naval industrial base. The program specifically supports the Golden Fleet Initiative to enhance the readiness and longevity of naval assets by addressing challenges in shipyards, maintenance depots, and supply chains. Key technology focus areas include composites, welding, AR/VR, digital shipyard support, and advanced packaging for rugged electronics. The solicitation is structured in two phases, with Phase I targeting immediate, high-value technological efforts and Phase II focusing on emerging future needs. The procurement process utilizes a two-step approach, beginning with a white paper submission followed by a down-select to a detailed full proposal consisting of technical and cost volumes. Awards may be issued as procurement contracts or Other Transaction Agreements (OTAs). For Phase I, the government plans to fund approximately 3 to 5 projects under 6.2 Applied Research with values between $500,000 and $3,000,000, and 5 to 10 projects under 6.3 with values between $1,500,000 and $5,000,000. Proposals are evaluated based on technical merit, Navy relevance and impact, ManTech appropriateness, and small business participation, rather than being evaluated against one another. The expected period of performance for projects is 1 to 2 years. Eligible offerors include both small and large businesses, provided they maintain an active SAM registration, a valid Unique Entity Identifier (UEI), and a CAGE code. A critical requirement for award is CMMC Level 2 (Self) certification. Additionally, an active DD-2345 Joint Certification Program (JCP) certification will be heavily weighed during the evaluation of organizational credentials. The response deadline for this solicitation is July 16, 2027. All submissions must be made through the designated ONR Submission Portal, and successful applicants must demonstrate a clear, quantifiable impact on the production or sustainment lifecycle along with a credible transition plan to a naval platform or industrial facility.

Office Of Naval Research

POSTED

DEADLINE

U.S. Army Contracting Command – Watervliet Arsenal (ACC-WVA) Organic Industrial Base (OIB) Modernization Commercial Solutions Opening (CSO)

Solicitation # W911PT26SC001

The U.S. Army Contracting Command – Watervliet Arsenal (ACC-WVA) has issued a Commercial Solutions Opening (CSO) solicitation, number W911PT26SC001, to modernize the Army's Organic Industrial Base. This competitive solicitation is open until September 30, 2027, and seeks innovative commercial products, technologies, and services to integrate manufacturing resources across the enterprise. Key objectives include linking legacy analogue systems with digital systems, expanding modeling and simulation, and improving the delivery of materiel solutions. The CSO is structured around specific Areas of Interest (AoIs) with varying closing dates through 2026, covering topics such as advanced cannon technology, ultrasonic test inspection equipment, electrical infrastructure improvements, chromium facility conversion, electronic access control systems, automated manufacturing of minor components, and automated cooling tower treatments. The acquisition process follows a multi-phased approach consisting of a written solution brief, an optional presentation or pitch, and a final request for a Commercial Solution Proposal (CSP). Evaluation is based on responsiveness to the AoI, technical merit, and price reasonableness. Eligible awards will be fixed-price contracts issued under FAR Part 12 Commercial Item Procedures. To be eligible, respondents must maintain an active registration in the System for Award Management (SAM) and possess a Unique Entity ID (UEI). All submissions must remain unclassified, and awarded contractors are required to use the Wide Area Work Flow (WAWF) system for invoicing.

POSTED

DEADLINE

in about 1 year

ITS4US Deployment Accelerator Pilot

Solicitation # 693JJ3-26-BAA-0007

The Department of Transportation's Intelligent Transportation Systems Joint Program Office is issuing a pre-solicitation notice for the ITS4US Deployment Accelerator Pilot under solicitation number 693JJ3-26-BAA-0007. This initiative aims to accelerate the replication of innovative technology solutions by awarding up to five operational pilots. Selected awardees will utilize open-source software and documentation from the ITS4US Deployment Program to develop, test, and deploy integrated technology solutions, thereby validating the maturity of these technologies for broader industry implementation. Participants will be integrated into a deployer cohort to receive technical support funded by the USDOT, allowing them to collaborate with peers to reduce costs and implementation time. This opportunity is managed by the Acquisition and Grants Management office in Washington, DC, and falls under NAICS code 541715. There are currently no set-aside restrictions for this solicitation.

693JJ3 Acquisition And Grants Mgt

POSTED

DEADLINE

NSWC-PHD MATAC OTA Request for Prototype Proposals: Router Chassis Design & Production

Solicitation # DIG-27-02-001

The Department of Defense, through the Commanding Officer at Port Hueneme, California, is seeking proposals under solicitation DIG-27-02-001 to design and produce a custom hardware chassis prototype. The project aims to resolve a physical compatibility issue where a new commercial network router does not fit into existing Tomahawk Equipment Cabinets. The objective is to create a secure chassis that allows the router to integrate with current power supplies and equipment racks without requiring a full system redesign. This opportunity is categorized under NAICS code 541715 and is managed via the NSWC-PHD MATAC OTA process. Proposals must be submitted by October 8, 2026. Following the successful development and testing of the prototype, the government intends to transition the project into a production phase for up to 60 units.

Commanding Officer

POSTED

DEADLINE

Receive Only Antennas for Antarctic Polar Orbiting Satellites

Solicitation # N6523626RE103

POSTED

DEADLINE

Market Research for Survivability, Assured Mobility, and Maneuver Support

Solicitation # W912CH_RFI_SAMMS

This sources-sought solicitation, issued by the Department of Defense under solicitation number W912CH_RFI_SAMMS, seeks market research to support research and development efforts for Survivability, Assured Mobility, and Maneuver Support material solutions. The project focuses on enhancing occupant-centric survivability through technologies such as armor and active protection systems, ensuring the ability to deploy and maneuver assets across diverse global climates, and maintaining freedom of movement via robotics, bridging systems, and combat engineer equipment. The opportunity is categorized under NAICS code 541715 and is managed by the office in Warren, Michigan. Interested parties must submit their responses by October 2, 2026. There is currently no set-aside designated for this requirement. Primary coordination for this effort is handled by David Asmar and Andrew Culkin.

POSTED

DEADLINE

Defense Logistics Information Research (DLIR) BAA

Solicitation # SP4701-26-B-0004

Dcso Philadelphia

POSTED

DEADLINE

in almost 5 years

Solicitation # DARPA-PS-26-127

The DARPA Perseus program, solicitation DARPA-PS-26-127, seeks innovative proposals to develop microscale ultra-high-vacuum (µUHV) systems that enable compact cold-atom devices and environmentally-decoupled ultra-high Q microelectromechanical (MEMS) and photonics devices. The primary technical goal is to create manufacturable vacuum packages with pressures below 10^-10 mbar that integrate cold-atom quantum sensors, MEMS, and photonic sensors while addressing critical challenges in vacuum packaging, materials, interconnects, and pumps. The program is structured into a three-month Phase 0 for security setup, a Phase 1 for technical work, and an optional Phase 2, with an estimated performance duration of 42 months starting around January 15, 2027. Awards will be made via Other Transaction (OT) for Prototype Agreements under 10 U.S.C. § 4022. Proposals are evaluated based on scientific and technical merit, potential contribution to the DARPA mission, and budget, price, and schedule. Technical merit assessments focus on innovation, feasibility, team expertise in manufacturing, and risk management. Mandatory requirements include the submission of an Intellectual Property Management Plan and a Commercialization and Transition Strategy. Compliance with cybersecurity standards is critical, specifically requiring a valid CMMC Level 2 self-assessment. Additionally, strict organizational conflict of interest (OCI) rules apply, particularly regarding Independent Verification and Validation (IV&V) partners. Full proposals must include Technical and Management Volumes and a detailed Price Volume, with a final submission deadline of September 23, 2026.

Defense Advanced Research Projects Agcy

POSTED

DEADLINE

Dual Purpose Weather Forecasting Solution

Solicitation # N6523626RE102

POSTED

DEADLINE

More opportunities from Department Of Health And Human Services → Advanced Research Projects Agency For Health (arpa-H)

Same awarding agency

ARPA-H Comprehensive Organ System Modeling in Outer Space (COSMOS) Innovative Solutions Opening

Solicitation # ARPA-H-SOL-26-165

The Advanced Research Projects Agency for Health (ARPA-H) has issued solicitation ARPA-H-SOL-26-165 for the Comprehensive Organ System Modeling in Outer Space (COSMOS) initiative. This program seeks to determine if microgravity in Low Earth Orbit (LEO) accelerates tissue aging in the brain, heart, uterus, and kidney across specific adult age brackets. If the Tissue Aging Rate in Space (TARIS) is proven to exceed the rate on Earth, the initiative aims to establish a high-throughput, autonomous drug screening platform in LEO that is more cost-effective and faster than terrestrial research and development. The government intends to award multiple Other Transaction (OT) Agreements to a diverse range of eligible entities, including universities, non-profits, and businesses of all sizes. The project is structured into two sequential phases: Phase I lasts 27 months, focusing on development and testing, while Phase II lasts 15 months and includes two planned space launches. Key deliverables include the quantification of TARIS using microphysiological systems (MPS), the creation of a licensable dataset of terrestrial and LEO twin data, and the establishment of a public-private partnership with a Fortune 100 pharmaceutical company. Technical requirements are stringent, requiring that at least 75 percent of experimental samples be MPS and that donor age brackets be strictly maintained at 30, 45, and 60 years (plus or minus 2 years). Proposals are evaluated based on technical innovation, risk mitigation, the potential to transform biomedicine, and commercial application viability. The government utilizes a milestone-based payment system where funding is tied to the achievement of quantitative exit criteria. Applicants must provide a comprehensive submission including a technical and management proposal, a task description document, a cost proposal, and certifications regarding eligibility and national policy compliance, including research security and cybersecurity standards.

Research and Development in Biotechnology (except Nanobiotechnology)

POSTED

DEADLINE

Data Management & Analysis SpecialistsThis subcontract opportunity with the Advanced Research Projects Agency for Health under the Department of Health and Human Services focuses on the development and execution of Data Management and Sharing Plans for prime contractors within the UNIQUE program. The selected provider will be responsible for designing data architectures to facilitate the sharing of research results while ensuring strict adherence to ARPA-H data standards. The project requires specialized expertise in large-scale scientific data management and sharing protocols to deliver a fully executed DMSP. Interested parties must respond by December 16, 2026, under NAICS code 541512.

Computer Systems Design Services

POSTED

DEADLINE

Technical Consultants & Subject Matter Experts (SMEs)This subcontract opportunity with the Advanced Research Projects Agency for Health under the Department of Health and Human Services seeks technical consultants and subject matter experts to support prime contractors on ARPA-H UNIQUE program projects. Selected experts will provide strategic guidance, technical reviews, and analysis focusing on the novelty of proposed work, intellectual property strategies, and the mitigation of technical risks. Qualified candidates must demonstrate a proven track record in specific research areas and complete all required organizational conflict of interest affirmations. The solicitation was posted on September 16, 2026, with a response deadline of December 16, 2026. This requirement falls under NAICS code 541611 for administrative management and consulting services.

Administrative Management and General Management Consulting Services

POSTED

DEADLINE

Specialized Laboratory & Facility ProvidersThis subcontract opportunity, issued by the Advanced Research Projects Agency for Health under the Department of Health and Human Services, seeks providers of specialized laboratories and facilities to support prime contractors on ARPA-H UNIQUE program projects. The selected providers must supply physical environments capable of biological containment and biosafety management, ensuring all facilities meet rigorous certification requirements and documented compliance for testing environments. The solicitation was posted on September 16, 2026, with a response deadline of December 16, 2026. Classified under NAICS code 541380, the contract focuses on delivering certified facility access essential for high-level biological research and testing.

Testing Laboratories and Services

POSTED

DEADLINE

Specialized Research & Development (R&D) ServicesThis subcontract for Specialized Research and Development Services supports the Advanced Research Projects Agency for Health under the Department of Health and Human Services. The selected provider will perform core scientific research, simulation, modeling, and experimental validation for prime contractors on ARPA-H UNIQUE program projects. The primary objective is to develop disruptive technology concepts and apply engineering and scientific practices to resolve technical adoption challenges. The contractor must possess relevant organizational experience and existing intellectual property to be eligible. Deliverables include technical reports, validated models, experimental data, and prototypes. This opportunity, categorized under NAICS code 541715, was posted on September 16, 2026, with a response deadline of December 16, 2026.

Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

POSTED

DEADLINE

Quantum AI Interpretation and Multimodal Fusion DevelopmentThis subcontract for the Advanced Research Projects Agency for Health under the Department of Health and Human Services focuses on the development of AI-driven reconstruction for the ARPA-H UNIQUE program. The scope of work involves creating physics-informed AI and quantum-aware reconstruction algorithms, utilizing PyTorch, TensorFlow, and high-performance computing clusters to achieve multimodal data fusion of anatomical and molecular information. Key technical deliverables include the implementation of uncertainty quantification for multidimensional quantum observables and the production of specialized reconstruction software and imaging representations. The project is categorized under NAICS code 541511 and was posted on September 16, 2026, with a response deadline of October 13, 2026.

Custom Computer Programming Services

POSTED

DEADLINE

Engineered Source Materials and Nanomaterials SupplyThis subcontract with the Advanced Research Projects Agency for Health under the Department of Health and Human Services focuses on the supply of engineered source materials and nanomaterials for prime contractors involved in ARPA-H UNIQUE program projects. The scope of work involves engineering materials to optimize the production of entangled 511 keV photon pairs and developing nanomaterials that function as sources or enhancers for quantum-derived biological signals. To ensure quality and safety, the provider must provide purity certifications and maintain strict nuclear regulatory compliance. The contract is categorized under NAICS code 325180 and was posted on September 16, 2026, with a response deadline of October 13, 2026.

Other Basic Inorganic Chemical Manufacturing

POSTED

DEADLINE

Quantum-Aware Detector and Physical System DevelopmentThis subcontract under the Advanced Research Projects Agency for Health (ARPA-H) focuses on the design and fabrication of quantum-aware detectors for prime contractors within the UNIQUE program. The primary objective is to develop decoherence-aware imaging architectures and verify the feasibility of measuring positronium-sensitive interactions through the use of controlled phantoms and 511 keV photon pair generators. The project culminates in the delivery of a functional physical imaging core and detector system designed to reproducibly measure quantum observables. Classified under NAICS code 334516, the opportunity was posted on September 16, 2026, with a response deadline of October 13, 2026.

Analytical Laboratory Instrument Manufacturing

POSTED

DEADLINE

Intellectual Property (IP) & BioSecure Act CounselThis subcontract opportunity with the Advanced Research Projects Agency for Health (ARPA-H) under the Department of Health and Human Services seeks legal counsel to support prime contractors on COSMOS projects. The selected provider will be responsible for managing intellectual property generated during Phase I and II, ensuring all activities comply with the BIOSECURE Act, and structuring IP to facilitate future Commercial Biopharmaceutical Partnerships. The role requires specialized legal expertise in biotechnology intellectual property and federal biotechnology laws to deliver comprehensive IP strategies and mandatory compliance certifications. Interested parties must respond by October 7, 2026, under NAICS code 541110.

Offices of Lawyers

POSTED

DEADLINE

Regulatory & GMP/GLP Compliance ConsultingThis subcontract for the Advanced Research Projects Agency for Health (ARPA-H) focuses on providing specialized regulatory and compliance consulting for prime contractors involved in COSMOS projects. The primary objective is to ensure that the development of microphysiological systems occurs under Good Manufacturing Practice and Good Laboratory Practice conditions to secure future FDA regulatory approval for reproducible disease models. The selected provider must possess extensive expertise in FDA regulatory standards specifically related to in vitro testing models. Key deliverables include the creation of regulatory compliance roadmaps and alignment reports to guide the project toward successful regulatory buy-in. The opportunity is categorized under NAICS code 541690, with a response deadline of October 7, 2026.

Other Scientific and Technical Consulting Services

POSTED

DEADLINE

Spaceflight Hardware Co-Engineering & IntegrationThis subcontract for the Advanced Research Projects Agency for Health involves the technical integration of MPS hardware for prime contractors on ARPA-H COSMOS projects. The scope of work includes co-engineering MPS support systems, specifically fluidics and housing, in collaboration with Commercial Service Providers for autonomous LEO platforms. A primary objective is ensuring all hardware remains compatible with commercial launch cargo parameters to deliver design-locked support housing. The project requires specialized expertise in space-rated hardware and microgravity fluidics. Interested parties must respond by October 7, 2026, under NAICS code 541330. This effort is managed under the Department of Health and Human Services to support advanced research in spaceflight hardware integration.

Engineering Services

POSTED

DEADLINE

Machine Learning (ML) & Data AnalyticsThis subcontract under the Advanced Research Projects Agency for Health (ARPA-H) focuses on the design and optimization of machine learning-assisted models for prime contractors on COSMOS projects. The primary objective involves processing Terrestrial Arm and LEO Twin data sets to identify critical patterns related to aging and tissue dysfunction, with a specific goal of optimizing models for high-throughput drug testing during Phase II. The project requires specialized proficiency in large-scale data set optimization and ML-assisted biological modeling. The successful contractor will be responsible for delivering fully analyzed data sets and functional machine learning models. This opportunity was posted on September 16, 2026, with a response deadline of October 7, 2026, falling under NAICS code 541511.

Custom Computer Programming Services

POSTED

DEADLINE

Ready to Pursue This Opportunity?

Get AI-powered intelligence on this solicitation and the ones like it

Every page of the solicitation package shredded into a compliance breakdown

AI-powered matching based on your capabilities and past performance

Competitor and incumbent history on the requirement

Automated alerts on amendments, Q&A deadlines, and award

Join 750+ contractors already using CLEATUS