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Cooperative Agreement for affiliated Partner with Rocky Mountain Cooperative Ecosystem Studies Unit

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G27AS00062Grant

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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The U.S. Geological Survey is seeking a CESU partner through a Cooperative Agreement to improve the efficiency and standardization of Real-Time Quaking Induced Conversion (RT-QuIC) assay data analysis for Chronic Wasting Disease (CWD) surveillance. The project aims to replace subjective interpretation with a robust, automated analytical pipeline. Key deliverables include the development of machine-learning models using LSTM, CNN-LSTM, or hybrid architectures to classify fluorescence curves, the creation of an open-source application using R-Shiny or Streamlit/Python for data ingestion and visualization, and the production of a peer-reviewed publication. To ensure reliability, the partner must perform cross-lab validations across at least three independent laboratories, including the USGS National Wildlife Health Center and the University of Georgia's Southeastern Cooperative Wildlife Disease Research Study. The opportunity has a total program funding and award ceiling of 145,220 dollars, with an anticipated period of performance from April 1, 2027, to March 31, 2032. Applications must be submitted via grants.gov by December 8, 2026, and must be submitted by an Authorized Organization Representative. Proposals are evaluated based on purpose and relevance, technical approach, qualifications and past performance, and budget clarity. Applicants must be registered in SAM.gov and provide a Unique Entity Identifier. The award is governed by DOI and USGS Terms and Conditions, and compliance with various 2 CFR 200 regulations regarding monitoring, reporting, and risk assessment is required.

General Info

USGS seeks a partner to automate CWD surveillance data analysis via machine learning.

Agency

Department Of The Interior → US Geological Survey

Estimated contract value

$1 to $145,220

Place of Performance

Not specified

Set-Aside

NONE

Documents

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DOCX, High priority: read this first1 page · sow
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PDF, High priority: read this first4 pages · sow
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PDF, High priority: read this first6 pages · current-and-pending-support-form
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DOCX, High priority: read this first1 page · project-abstract-summary
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PDF, High priority: read this firstrfp
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Organization & Contact Information

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AgencyDepartment Of The Interior → US Geological Survey
Contacts1 person available
OfficeUSA
Organization / Agency
Department Of The Interior → US Geological Survey
Office AddressUSA
Contacts

Full Description

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The USGS is offering a funding opportunity to a CESU partner for research focused on improving the efficiency and standardization of Real-Time Quaking Induced Conversion (RT-QuIC) assay data analysis for Chronic Wasting Disease (CWD) surveillance, research, and management.

CWD continues to expand geographically and intensify in prevalence, placing growing strain on wildlife management agencies. RT-QuIC is among the most promising tools for the detection of low-level CWD prions, but current analytical approaches lack standardization and rely heavily on subjective interpretation. This opportunity supports development of a robust, automated, and reproducible analytical pipeline that improves efficiency, repeatability, and inter-laboratory consistency.

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