transgenic mouse

PRE-SOLICITATION NOTICE OF INTENT NON-COMPETITIVE INTRODUCTION PURSUANT TO FAR Subpart 5.2-Synopses of Proposed Contract Actions, THIS IS A PRE-SOLICITATION NOTICE OF A PROPOSED CONTRACT TO ACTION. THIS IS A PRE-SOLICITATION NON-COMPETITIVE NOTICE OF INTENT TO AWARD A CONTRACT OR PURCHASE ORDER WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME). The National Institute on Drug Abuse (NIDA), Station Support Contracts and Simplified Acquisitions Branch (SS/SA) on behalf of the National Institute on Drug Abuse intends to negotiate and award a contract for transgenic mouse. NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE The intended procurement is classified under NAICS code 541380 with a Size Standard of $15M. REGULATORY AUTHORITY The resultant contract will include all applicable provisions and clauses of the Federal acquisition Requlation (FAR) in effect through the Federal Acquisition Circular (FAC) 05-95. STATUTORY AUTHORITY This acquisition is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13-Simplified Acquisition Procedures, Subpart 13.106-1 (b) (1), Soliciting from a single source. Non-Competitive (Single-sole Source) Determination: This notice of proposed acquisition is posted as an intent to award a purchase order on a non-competitive basis to: Ingenious Targeting Laboratory 2200 Smithtown Avenue Ronkonkoma, NY 11779 The essential characteristics of the transgenic model that limit the availability to Ingenious Targeting Laboratory are the unique design, genetic targeting approaches and targeting vectors specifically owned by the specified vendor. DESCRIPTION OF REQUIREMENT Project Description slc30a3-cre expressing mouse Purpose and Objectives The Biobehavioral Imaging and Molecular Neuropsychopharmacology Unit at NIDA studies the role of zinc in neurobiology. Transgenic mice can serve as powerful tools for specific targeting of zinc neurons in the brain which currently cannot be targeted with other methods. The Biobehavioral Imaging and Molecular Neuropsychopharmacology Unit at NIDA is in need of a unique transgenic mouse model for selective targeting of zinc containing neurons. The specific transgenic mouse model will need to express cre recombinase in slc30a3 cells and also offer the ability for conditional deletion of slc30a3. Period of Performance Estimated, June 15, 2017 to January 31, 2018. CLOSING STATEMENT This synopsis is not a request for competitive proposals. However, interested parties may identify their interest and capability to respond to this notice. Responses to this notice must include sufficient information to establish the interested parties' bona-fide capabilities of providing the product or service. The price quote shall include: unit price, list price, shipping and handling costs, delivery days after contract award, delivery terms, prompt payment discount terms, F.O.B. Point (Destination or Origin), product or catalog number(s); product description; and any other information or factors that may be considered in the award decision. Such factors may include: past performance; special features required for effective program performance; trade-in considerations; probable life of the item selected as compared with that of a comparable item; warranty considerations; maintenance availability; and environmental and energy efficiency considerations. In addition the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement. All responses must be received by May 24, 2017 at 12:00 PM Eastern Standard Time and must reference number HHS-NIH-NIDA-NOI-17-330. Responses must be submitted electronically to Sneha Patel, sneha.patel@nih.gov and must reference the solicitation number HHS-NIH-NIDA-NOI-17-330 on your electronic request. FAX requests are not accepted. All responsible sources may submit a capability statement, proposal, or quotation, which shall be considered by the agency. RE-SOLICITATION NOTICE OF INTENT NON-COMPETITIVE INTRODUCTION PURSUANT TO FAR Subpart 5.2-Synopses of Proposed Contract Actions, THIS IS A PRE-SOLICITATION NOTICE OF A PROPOSED CONTRACT TO ACTION. THIS IS A PRE-SOLICITATION NON-COMPETITIVE NOTICE OF INTENT TO AWARD A CONTRACT OR PURCHASE ORDER WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME). The National Institute on Drug Abuse (NIDA), Station Support Contracts and Simplified Acquisitions Branch (SS/SA) on behalf of the National Institute on Drug Abuse intends to negotiate and award a contract for transgenic mouse. NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE The intended procurement is classified under NAICS code 541380 with a Size Standard of $15M. REGULATORY AUTHORITY The resultant contract will include all applicable provisions and clauses of the Federal acquisition Requlation (FAR) in effect through the Federal Acquisition Circular (FAC) 05-95. STATUTORY AUTHORITY This acquisition is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13-Simplified Acquisition Procedures, Subpart 13.106-1 (b) (1), Soliciting from a single source. Non-Competitive (Single-sole Source) Determination: This notice of proposed acquisition is posted as an intent to award a purchase order on a non-competitive basis to: Ingenious Targeting Laboratory 1301 Arrow Point Drive Cedar Park, TX 78613 The essential characteristics of the transgenic model that limit the availability to Ingenious Targeting Laboratory are the unique design, genetic targeting approaches and targeting vectors specifically owned by the specified vendor. DESCRIPTION OF REQUIREMENT Project Description slc30a3-cre expressing mouse Purpose and Objectives The Biobehavioral Imaging and Molecular Neuropsychopharmacology Unit at NIDA studies the role of zinc in neurobiology. Transgenic mice can serve as powerful tools for specific targeting of zinc neurons in the brain which currently cannot be targeted with other methods. The Biobehavioral Imaging and Molecular Neuropsychopharmacology Unit at NIDA is in need of a unique transgenic mouse model for selective targeting of zinc containing neurons. The specific transgenic mouse model will need to express cre recombinase in slc30a3 cells and also offer the ability for conditional deletion of slc30a3. Period of Performance Estimated, June 15, 2017 to January 31, 2018. CLOSING STATEMENT This synopsis is not a request for competitive proposals. However, interested parties may identify their interest and capability to respond to this notice. Responses to this notice must include sufficient information to establish the interested parties' bona-fide capabilities of providing the product or service. The price quote shall include: unit price, list price, shipping and handling costs, delivery days after contract award, delivery terms, prompt payment discount terms, F.O.B. Point (Destination or Origin), product or catalog number(s); product description; and any other information or factors that may be considered in the award decision. Such factors may include: past performance; special features required for effective program performance; trade-in considerations; probable life of the item selected as compared with that of a comparable item; warranty considerations; maintenance availability; and environmental and energy efficiency considerations. In addition the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov." A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement. All responses must be received by May 24, 2017 at 12:00 PM Eastern Standard Time and must reference number HHS-NIH-NIDA-NOI-17-330. Responses must be submitted electronically to Sneha Patel, sneha.patel@nih.gov and must reference the solicitation number HHS-NIH-NIDA-NOI-17-330 on your electronic request. FAX requests are not accepted. All responsible sources may submit a capability statement, proposal, or quotation, which shall be considered by the agency.