Vehicle Recompete: BPCA-PTN — Idc 75N94018D00003
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The Best Pharmaceuticals for Children Act - Pediatric Trials Network (BPCA-PTN) is an Indefinite Delivery Vehicle managed by the National Institutes of Health NICHD under the Department of Health and Human Services. This full-recompete contract, identified as vehicle 75N94018D00003, has an IDV ceiling of 96 million dollars and an ordering period that extends through June 3, 2026. There was no set-aside used for this procurement. Duke University has been a primary recipient of significant task orders under this vehicle, focusing on innovative trial designs, assay developments in pediatric therapeutics, and pharmacoepidemiology studies. Key initiatives include the integration of patients with Down syndrome into pharmacology-based clinical trials and the identification of gaps in off-label drug use in children through systematic literature reviews and population PK modeling. These efforts aim to advance pediatric science by utilizing clinically relevant outcomes, biomarkers, and real-world data.
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Not specifiedSet-Aside
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Igf::Ot::Igf nichd best pharmaceuticals for children act - pediatric trials network (bpca-ptn) 2018-2026 Original Solicitation: NIHNICHDOPPTB20182 IDV Ceiling: $96,000,000 Set-Aside: No set aside used. Contracting Office: National Institutes Of Health Nichd Agencies: Department of Health and Human Services Classification: full-recompete (Confidence: high - 85/100)
Top task orders by value: - TO PERFORM INNOVATIVE TRIAL DESIGNS WITH CLINICALLY RELEVANT OUTCOMES SUCH AS ENDPOINTS, BIOMARKERS, AND EPIDEMIOLOGY DATA INCLUDED ASPART OF EVERY PROTOCOL, TO OBTAIN COMPREHENSIVE AND COMPARATIVE ANALYSIS OF THE DATA FOR THE ADVANCE OF SCIENCE AND ($10,583,491) - DUKE UNIVERSITY - BPCA INNOVATIVE TRIAL DESIGNS AND ASSAY DEVELOPMENTS IN PEDIATRIC THERAPEUTICS ($8,783,682) - DUKE UNIVERSITY - TO PROVIDE A PLATFORM FOR THE INCLUSION OF PATIENTS WITH DOWN SYNDROME INTO THE PHARMACOLOGY-BASED CLINICAL TRIALS. THE GOALS ARE TO RECRUIT THIS PATIENT POPULATION INTO THE PEDIATRIC TRIALS NETWORK OPPORTUNISTIC STUDY MODEL AND TO DEVELOP A TRAINING ($6,798,777) - DUKE UNIVERSITY - THE PURPOSE OF THIS TASK ORDER IS TO IDENTIFY THE REMAINING GAPS IN OFF-LABEL USE IN CHILDREN AND TO DESIGN CLINICAL RESEARCH (SYSTEMATIC LITERATURE REVIEWS, EPIDEMIOLOGY STUDIES, POPULATION PK MODELING STUDIES, AND INNOVATIVE SAFETY AND EFFECTIVENES ($5,759,708) - DUKE UNIVERSITY - BPCA PHARMACOEPIDEMIOLOGY (REAL WORLD DATA) STUDIES ($2,394,965) - DUKE UNIVERSITY
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