Marie D. Sepe

Marie D. Sepe serves as a Contract Specialist for the Defense Threat Reduction Agency (HDTRA1), where she plays a critical role in executing complex acquisitions that support the agency’s mission to counter weapons of mass destruction and mitigate emerging national security threats. She manages the full lifecycle of procurement actions—from market research and solicitation development to contract award and administration—primarily focusing on advanced technical systems, cybersecurity infrastructure, and analytical software solutions. Her work directly enables HDTRA1’s scientific and operational teams to detect, deter, and neutralize chemical, biological, radiological, nuclear, and high-yield explosive threats through timely and compliant contracting. Marie maintains longstanding relationships with key contractors including TECHTRANS INTERNATIONAL INC, BATTELLE MEMORIAL INSTITUTE, AERIS LLC, APPLIED RESEARCH ASSOCIATES, INC., and AMAZON WEB SERVICES, INC. These partnerships reflect a preference for established technical providers with deep expertise in defense science, threat modeling, and cloud-based secure computing environments. Her contracting approach emphasizes performance-based outcomes, technical rigor, and risk mitigation, often involving multiple-award task order contracts and indefinite-delivery/indefinite-quantity mechanisms to ensure agile responsiveness to evolving threats. Her procurement patterns show a strong preference for open competition, with 85.7% of awards issued without set-aside designations, reflecting the highly specialized and mission-critical nature of HDTRA1’s requirements. While small business participation is limited to 14.3% of awards, these are typically structured as Total Small Business Set-Asides under FAR 19.5, indicating targeted support for qualified small firms capable of meeting stringent technical and security standards. Marie’s portfolio is exclusively focused on NAICS 423430, encompassing the procurement of computer systems, specialized software, and related IT infrastructure essential to threat intelligence, data analytics, and secure communications. Her expertise lies in acquiring cutting-edge computational tools, secure cloud platforms, and integrated defense-grade software solutions that underpin HDTRA1’s technical operations and scientific research initiatives.