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COLUMBUS NANOWORKS, INC.

UEI: DKV6HXMPSJJ5CAGE: 3Y4B8

COLUMBUS NANOWORKS, INC. is a federal contractor, registered under UEI DKV6HXMPSJJ5 and CAGE code 3Y4B8. It has been awarded $5,042,930 across 10 federal contracts. Primary work spans Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology), Biological Product (except Diagnostic) Manufacturing, and Unknown NAICS. Top awarding agencies include Department Of Health And Human Services and Department Of Defense.

Contact Information

Registration and classification details

Registration

UEI Code

DKV6HXMPSJJ5

CAGE Code

3Y4B8

Entity Structure

Corporate Entity (Not Tax Exempt)

Established

N/A

Business Classifications

2XMFXS

NAICS Codes

325413In-Vitro Diagnostic Substance Manufacturing(Primary)
325414Biological Product (except Diagnostic) Manufacturing
334516Analytical Laboratory Instrument Manufacturing
541690Other Scientific and Technical Consulting Services
541713Research and Development in Nanotechnology
+2 more

Federal Contracting Overview

Award totals, agency breakdown, NAICS distribution, and geographic footprint.

AI Capability Profile

Columbus Nanoworks, Inc. specializes in advanced research and development of biosensing platforms and nanoscale imaging systems for biomedical applications. The company leverages machine learning, quantum-based detection techniques, and fluorescent nanodiamonds to enable sensitive, label-free biomar...

Columbus Nanoworks, Inc. specializes in advanced research and development of biosensing platforms and nanoscale imaging systems for biomedical applications. The company leverages machine learning, quantum-based detection techniques, and fluorescent nanodiamonds to enable sensitive, label-free biomarker analysis—particularly for microRNAs and cortisol—as part of human performance monitoring and in vivo biological imaging. Their technical expertise spans the design and fabrication of nanostructured biosensors, computational posture analysis, and the integration of optical detection systems with biological assays, positioning them at the intersection of physical sciences and life sciences R&D. A key differentiator is their ability to translate nanomaterial innovations into functional biomedical tools, bridging laboratory prototypes with deployable diagnostic and monitoring platforms. The contractor has delivered projects for the Department of Health and Human Services and the Department of Defense, consistently supporting SBIR-phase research initiatives focused on non-diagnostic biological applications. For HHS, they have developed fluorescent nanodiamonds for biological imaging and machine learning-driven posture analytics, while for DoD, they engineered quantum-enabled nanobiosensors to detect low-abundance biomarkers relevant to soldier health and performance. These engagements reflect a pattern of responsive, mission-driven R&D aligned with federal health and human performance priorities. Their primary industry focus lies in NAICS 541715 for physical and engineering sciences R&D and 325414 for biological product manufacturing, where they operate as a niche innovator in non-diagnostic nanobiotechnology. Their work supports defense and public health sectors through novel sensor platforms and imaging agents, avoiding commercial diagnostics to maintain a specialized, government-focused market position. Columbus Nanoworks, Inc. is a small business based in Columbus, Ohio, with no federal certifications on record. Their geographic presence is localized but their technical work serves national-level defense and health research missions through targeted federal contracts.

Key Performance Metrics

Awards Count

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Award Analytics & Distribution

Awards by Agency
Department Of Health And Human Services$3.8M75.2%
Department Of Defense$1.3M24.8%
Awards by NAICS
541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)$2.1M41.9%
325414 - Biological Product (except Diagnostic) Manufacturing$1.5M29.7%
- Unknown NAICS$949.1K18.8%
541713 - Research and Development in Nanotechnology$300.0K6%
325413 - In-Vitro Diagnostic Substance Manufacturing$182.7K3.6%
Awards by Agency Over Time
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Awards by Place of Performance

Open opportunities in COLUMBUS NANOWORKS, INC.'s top NAICS codes and agencies

NAICS: 325413
New
DIBBS
CONTROL, RESPIRATORY PA
Solicitation # SPE2DS-26-T-311F
The BioFire RP2.1/RP2.1plus Control Panel is a synthetic nucleic acid-based quality control product consisting of 12 vials, each containing 300 microliters of a non-infectious buffer solution with stabilizers and preservatives. It is designed for in vitro use with the FilmArray instrument to monitor the detection and identification of respiratory pathogens during RP2.1 panel testing. Each kit provides sufficient reagent for six quality control runs, including six positive and six negative controls. The product requires strict frozenstorage between -25°C and -15°C (-13°F to 5°F) and has a non-extendable shelf life of 18 months, with no more than two months allowed to have passed from the date of manufacture to delivery to the government. Labeling must include the date of manufacture, expiration date, contract number, and lot number in compliance with Medical Marking Standard No. 1, which supersedes MIL-STD-129. Packaging must meet commercial standards, ensuring protection against damage, with exterior containers suitable for safe transport at the lowest cost to the specified delivery point. The item is governed by DLA technical and packaging requirements, including RS013 for shelf life, RP001 for packaging standards, and RD003 for potential covered defense information. The National Stock Number is 6550-01-690-4435, with a procurement quantity of three kits under solicitation SPE2DS-26-T-311F, with a delivery deadline of 83 days after award.
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NAICS: 325414
New
DIBBS
TEST KIT, BACTERIA D
Solicitation # SPE2DS-26-T-310W
The contract is for the procurement of 25 units of the API 20 E test kit, designed for the identification of Enterobacteriaceae and other gram-negative rods, under the NSN 6550-01-507-3726. Each purchase group (PG) equals 25 units, and the full order consists of exactly one PG. The product must be delivered within five days of contract award, with delivery terms specified as FOB destination, and no quantity variance is permitted. Strict shelf-life requirements apply: no more than three months may have elapsed from the date of manufacture to the date of delivery, and the item has a non-extendable shelf life of 18 months, classified as a TYPE I CODE K item. The test kits require refrigerated storage between 2 and 8 degrees Celsius at all times. Packaging must comply with commercial standards and Medical Marking Standard No. 1, superseding MIL-STD-129, with each unit sealed in protective containers and shipped in suitable exterior packaging to ensure safe delivery at the lowest freight rate. The product is regulated by the FDA, and the contracting official must submit a referral via EBS for confirmation, including manufacturer and part number details. The manufacturer is bioMérieux Inc with part number 20100. Technical and quality requirements are governed by the DLA Master List, and packaging, marking, and information security controls, including potential covered defense information, are mandated per applicable DLA directives. All documentation and compliance must align with the solicitation SPE2DS-26-T-310W, issued under NAICS code 325414 by the Department of Defense.
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NAICS: 541715
New
Federal
REQUEST FOR WHITE PAPERS BAA TOPIC: Topic 13. Biotechnology, “Controlling polymicrobial environments as a strategy for defeating harmful organisms while promoting the growth of beneficial organisms”
Solicitation # W912CG-26-S-BIOTECH
The U.S. Army Combat Capabilities Development Command Soldier Center is soliciting white papers under Broad Agency Announcement W911QY-25-R-0023 to advance biotechnological research focused on controlling polymicrobial environments to suppress harmful organisms while fostering beneficial ones, with specific emphasis on developing phage-based hygiene wipes to prevent urinary tract infections in female Warfighters. The effort aims to design, optimize, and test a cosmetic-grade formulation that maintains bacteriophage viability under extreme thermal conditions—particularly at 45°C for four weeks—while being compatible with natural cellulosic wipes, resealable packaging, and regulatory standards under the Modernization of Cosmetic Regulation Act. The proposed formulation must include a phage cocktail at a minimum titer of 1E8 PFU/ml, a neutral pH buffer, preservatives effective at pH 7–8, stabilizers like polyvinyl alcohol, and moisturizing agents, all without compromising phage activity. Up to three formulation iterations are expected, culminating in the delivery of 100 prototype wipe packs—50 with active phage and 50 without—for field-relevant testing. Submission begins with a white paper, limited to five pages, detailing the technical approach, management structure, relevant past performance, and a rough order of magnitude cost estimate covering a 12-month base period with two optional 12-month extensions. Only white papers submitted electronically by 31 August 2026, 5:00 p.m. EDT, to the designated email address will be considered eligible for further invitation to submit a full proposal. Evaluation will prioritize scientific merit, management capability, alignment with Army mission needs, and cost-effectiveness, with feedback provided to submitters. Selection of white papers does not guarantee funding or a contract award, as decisions are contingent on budget availability and program priorities. The government reserves the right to cancel the solicitation at any time without obligation. Award mechanisms may include a contract, grant, or cooperative agreement, though a contract is the intended outcome. Formal proposals will only be requested from top-scoring white papers, and no further communication with government technical personnel is permitted after submission of a full proposal.
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NAICS: 541715
New
Federal
Airborne and Mobile Measurements to support NOAA ARL’s Research on Meteorology and Atmospheric Chemistry
Solicitation # 145022-26-0017
The contract solicits specialized airborne and mobile measurement services to support NOAA’s atmospheric research in key urban regions, including Washington DC/Baltimore and New York City, with additional focus on methane emissions characterization and boundary layer analysis using mobile ceilometers and drone-mounted analyzers. The contractor must provide fully equipped research aircraft, qualified flight crews, and operational support to conduct multiple research flights in compliance with FAA regulations, collecting high-quality meteorological, chemical, and navigational data that will be integrated with NOAA’s existing aircraft, satellite, and surface monitoring systems. Also required is the deployment of a mobile ceilometer for continuous planetary boundary layer height measurements and, when requested, FAA-compliant unmanned aircraft systems equipped with methane/ethane analyzers to quantify point source emissions. The effort includes analysis of mobile laboratory data collected during the 2026 SOCCER-AQ field campaign in Boston to identify and quantify urban emission sources, compare observations with emissions inventories and models, and produce peer-reviewed publications and conference presentations. Administrative coordination is a core component, with the prime contractor responsible for managing all subcontractors, overseeing financial and scheduling milestones, consolidating deliverables, and ensuring full compliance with contract terms through a firm fixed-price, all-or-none award. This is a small business set-aside under NAICS code 541715, with a performance period from September 1, 2026, to August 31, 2027, and payment terms of Net 30. All work is centered at NOAA’s Advanced Systems and Modeling Division in Riverdale Park, Maryland, with deliverables due by the end of the period of performance. Quotes must be submitted electronically by August 14, 2026, to the designated NOAA point of contact, and pricing must be provided in accordance with the SF18 form or company letterhead, including monthly and annual breakdowns. The government explicitly states it will not accept responsibility for non-receipt of quotes, and the awardee must confirm receipt. Wage determinations referenced under WD #2015-4265 and WD #2015-4187 apply, and administrative coordination responsibilities—including subcontract management, invoice processing, and final documentation—must be fulfilled by the prime contractor, though technical oversight of scientific tasks remains with NOAA and subcontractors. All contract provisions and clauses are accessible via acquisition.gov, and the solicitation does not require SAM representations that are not included in the official solicitation documents.
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NAICS: 541715
New
Federal
AJ11--(Late) Research Services - ID Neuroimaging Biomarkers for Brain Connectivity - BRONX | EDA: 9/25/26
Solicitation # 36C24E26R0022
The Department of Veterans Affairs, James J. Peters VA Medical Center, intends to award a sole-source contract to the New Jersey Institute of Technology (NJIT) for specialized research services focused on identifying neuroimaging biomarkers for brain connectivity, in support of an ongoing VA Merit Award. This action is justified under 41 U.S.C. §3304(a)(3) and FAR 6.103-3, as NJIT is the only entity with the unique, four-year-developed expertise, proprietary datasets, and validated methodologies essential to the research's continuity and scientific integrity. NJIT’s world-class proficiency in fNIRS-based brain connectivity research, backed by multiple peer-reviewed publications and sustained collaboration with VA investigators, cannot be replicated by other institutions, even those with fNIRS capabilities, due to the absence of proximity, shared data infrastructure, and proven technical proficiency. Any other source would introduce unacceptable delays or compromise the research outcomes. The solicitation number is 36C24E26R0022, with a posted date of August 5, 2026, and a deadline for capability statements of August 10, 2026, at 4:00 PM EST. While this is a notice of intent and not a competitive solicitation, any responsible source believing it can meet the requirement may submit a capability statement to Lynn Portman at lynn.portman@va.gov by the deadline; telephone responses are not accepted. The NAICS code is 541715, and the contracting office is located in Pittsburgh, PA, under the Rpo East (36C24E) organization. The government retains sole discretion to determine whether to proceed without competition, and no further opportunities for bid submission will be provided.
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NAICS: 541715
New
Federal
ARMY OPEN SOLICITATION (AOS)
Solicitation # W9128Z-25-S-A002
The Army Open Solicitation (AOS), identified by solicitation number W9128Z-25-S-A002, is an indefinite, open solicitation issued by the U.S. Army Contracting Command – Aberdeen Proving Ground to rapidly acquire innovative commercial technologies and research-driven solutions across all Army mission areas. Designed to revitalizing the industrial base and enhancing Warfighter lethality, the solicitation leverages a flexible acquisition framework under multiple FAR, DFARS, and U.S. Code authorities, including Other Transactions, Commercial Solutions Opening, and prototype authorities. It supports both Active Capability Gap submissions and periodic Calls for Solutions, with responses evaluated based on technical merit, feasibility, schedule, price estimation, viability, and desirability using a trade-off approach rather than lowest price technically acceptable. The solicitation remains open indefinitely until canceled, with recent amendments through March 2026 expanding and clarifying Army Example Areas, refining submission procedures, and updating contracting information including Active Capability Gap mailboxes. All submissions must adhere to strict formatting requirements, including a single PDF submission not exceeding five pages or fifteen slides, with mandatory inclusion of an executive summary, company information, and rough order of magnitude cost and schedule estimates. Offerors must be registered in SAM, use WAWF for invoicing, and comply with stringent data storage and security requirements, including U.S.-only data hosting and full organizational conflict of interest disclosures. The solicitation encourages participation from small businesses, nontraditional defense contractors, and nonprofit research institutions, with specific certifications required through the Affirmation of Business Status Certification. Performance may occur at government facilities including Aberdeen Proving Ground and other CONUS/OCONUS locations as directed, with award timing anticipated in fiscal year 2026, and support expected through 2032. No fixed contract value is provided, as pricing is determined through competitive evaluation of commercial proposals under the solicitation's open-ended structure.
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NAICS: 541715
New
Federal
ATEC HQ 002 - Wide-Field Optical Data Fusion Modernization
Solicitation # ATEC_RIW26_002
The Army Contracting Command - Aberdeen Proving Ground, acting on behalf of the Army Test and Evaluation Command, has issued a Call for Solutions to advance Wide-Field Optical Data Fusion Modernization under solicitation number ATEC_RIW26_002. This initiative seeks innovative technical approaches to enhance the integration and processing of wide-field optical data, targeting improvements in operational effectiveness and system performance. Submissions must adhere to the guidance detailed in the CfS document and align with the overarching framework of the Army Open Solicitation W9128Z-25-S-A002. All communications regarding this solicitation must include the specific subject line format: “Call for Solution - [Your Company Name] - ATEC_RIW26_002” to ensure proper routing and processing. The deadline to submit questions is August 10, 2026, at 1500 EDT, and all proposals for Phase 1 are due by August 19, 2026, at 1500 EDT. The solicitation is managed by the Department of Defense through the ACC-APG office located in Aberdeen Proving Ground, Maryland, with primary point of contact Dennis Beauclair, Jr., and secondary contact Whitney J. Jackson. Proposers are directed to review both the Call for Solutions and the associated Army Open Solicitation posting for complete requirements, evaluation criteria, and submission protocols. Responses must be submitted through the designated SAM.gov portal linked in the official posting.
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NAICS: 541715
New
Grant
US Travelers Health Research, Surveillance, Communication, and Outreach Network
Solicitation # RFA-CK-26-036
The Centers for Disease Control and Prevention is seeking to establish a comprehensive network to enhance the health and safety of U.S. travelers internationally by improving pre-travel preparedness, real-time health information access, and rapid research capacity. The initiative focuses on empowering both travelers and healthcare providers with up-to-date, high-quality travel health guidance through scalable digital platforms including electronic medical records, web applications, and mobile tools. These technologies will facilitate the systematic collection of health data before, during, and after travel to identify emerging risks and support timely public health responses. The program aims to strengthen the role of primary care providers in travel medicine by expanding their awareness and equipping them with evidence-based tools to deliver accurate recommendations to international travelers. The network will serve as a foundational platform for ongoing surveillance and research into global health threats affecting U.S. travelers, enabling proactive identification and mitigation of infectious and environmental risks. By integrating data from diverse sources and fostering collaboration across healthcare systems, the project seeks to create a dynamic, responsive infrastructure that informs both individual travel decisions and broader public health policy. This effort is being issued under solicitation RFA-CK-26-036 with a submission deadline of November 5, 2026, and is managed by the CDC within the U.S. Department of Health and Human Services, with inquiries directed to the designated point of contact.
Centers For Disease Control And Prevention

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NAICS: 325413
New
DIBBS
CONTROL SET, GLUCOSE
Solicitation # SPE2DS-26-T-308J
The control set for glucose is designed for use with the Accu-Chek Inform II system and includes two 2.5 mL vials—one each of Level 1 and Level 2 control solutions—to ensure accurate calibration and performance verification of test strips. It must be stored between 39 and 86 degrees Fahrenheit (4 to 30 degrees Celsius) and must not be frozen. The item is issued as a single unit and is subject to strict medical procurement standards, including commercial packaging requirements that ensure protection from damage and safe delivery by common carriers. All units must be marked in accordance with Medical Marking Standard No. 1, which supersedes MIL-STD-129, and include the date of manufacture, expiration or retest date, contract number, and lot number. The item has a non-extendable shelf life of 24 months, and no more than three months may have elapsed from the date of manufacture to the date of government delivery. Technical and quality requirements referenced under R and I numbers are governed by the DLA Master List, with revision standards tied to solicitation or award dates depending on acquisition size. This item is classified as a Type I (Code M) medical supply, and all labeling, packaging, and marking must comply with the latest version of MMS1C. The NSN is 6550-01-642-5011, the solicitation number is SPE2DS-26-T-308J, and delivery is required within 20 days after order award to Fort Campbell, with the contract managed by the Department of Defense under the Medical Supply Chain.
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