CRESTONE, INC.
CRESTONE, INC. is a federal contractor, registered under UEI EDSLAP2J1BL8 and CAGE code 5RDJ6. It has been awarded $67,610,270 across 12 federal contracts. Primary work spans Research and Development in Biotechnology (except Nanobiotechnology), Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology), and Unknown NAICS. Top awarding agencies include Department Of Health And Human Services and Other agencies (2 agencies, <0.5% each).
Contact Information
Registration and classification details
Registration
UEI Code
EDSLAP2J1BL8CAGE Code
5RDJ6Entity Structure
Corporate Entity (Not Tax Exempt)Established
N/ABusiness Classifications
NAICS Codes
Federal Contracting Overview
Award totals, agency breakdown, NAICS distribution, and geographic footprint.
AI Capability Profile
CRESTONE, INC. specializes in preclinical and clinical-stage research and development across the life sciences, with deep expertise in small-molecule drug discovery, laboratory synthesis, and translational bioassay validation. The company supports federal agencies by advancing novel therapeutic cand...
CRESTONE, INC. specializes in preclinical and clinical-stage research and development across the life sciences, with deep expertise in small-molecule drug discovery, laboratory synthesis, and translational bioassay validation. The company supports federal agencies by advancing novel therapeutic candidates from early-stage optimization through Investigational New Drug (IND) filing readiness, employing rigorous biochemical, pharmacological, and analytical methodologies. Their technical capabilities include medicinal chemistry synthesis, in vitro and in vivo testing protocols, pharmacokinetic/pharmacodynamic profiling, and regulatory-compliant data package development for NIH and VA programs. CRESTONE differentiates itself through its focused execution in biotechnology and physical sciences R&D, particularly in bridging laboratory innovation with clinical development pathways under strict federal compliance frameworks. The contractor maintains a consistent presence with the Department of Health and Human Services, primarily supporting National Institutes of Health initiatives in infectious disease and therapeutic development, as well as the Department of Veterans Affairs, where they deliver specialized laboratory services for biomedical research. These relationships reflect a pattern of sustained engagement in mission-critical, science-driven programs requiring precision, reproducibility, and regulatory alignment. CRESTONE operates primarily under NAICS 541714 and 541715, focusing on non-nanotechnology biotechnology research and broader physical/engineering life sciences R&D. Their market positioning centers on niche, high-impact therapeutic discovery efforts, particularly in small-molecule optimization and preclinical validation, serving the federal biomedical innovation ecosystem without competing in broad-spectrum contract research. As a small business structured as a 2L entity based in Boulder, Colorado, CRESTONE operates with agility and scientific rigor. The company holds no formal government certifications but leverages its technical depth and domain-specific experience to deliver high-value R&D services within the federal life sciences market.
Key Performance Metrics
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