PACIFIC BIOSCIENCES OF CALIFORNIA, INC

Pacific Biosciences of California, Inc. specializes in the design, manufacture, and support of long-read DNA and RNA sequencing instrumentation, with deep expertise in single-molecule real-time (SMRT) sequencing technology. The company delivers end-to-end genomic solutions, including high-accuracy sequencers such as the REVIO and Sequel II systems, along with associated reagent kits, consumables, and precision maintenance services. Their technical capabilities encompass instrument calibration, preventive maintenance, repair of complex optical and microfluidic subsystems, and integration of sequencing workflows for research and diagnostic applications. Key differentiators include proprietary HiFi sequencing chemistry, ultra-long read lengths for complex genome assembly, and robust service infrastructure tailored to mission-critical genomic research environments. The contractor maintains strong, recurring relationships with the Department of Health and Human Services and the Department of Agriculture, providing sequencing instruments, reagents, and sustained technical support for genomic research, agricultural genomics, and pathogen surveillance. For HHS, work often supports NIH institutes in life sciences R&D and clinical sequencing applications; for USDA, efforts focus on livestock, plant, and microbial genome analysis. The Department of Defense engages the contractor for advanced genomic analysis in biodefense and medical readiness contexts. Core industry focus lies in analytical laboratory instrument manufacturing (NAICS 334516), with complementary activity in biological product manufacturing and life sciences R&D. The company positions itself as a leader in next-generation sequencing hardware and services for government-funded genomics initiatives, serving public health, agricultural science, and defense research markets. Pacific Biosciences of California, Inc. is a commercial entity headquartered in Menlo Park, California, with no federal certifications on record. Its government market presence is anchored in high-precision life sciences instrumentation and service delivery, serving federal research and operational laboratories nationwide.