TEMPUS AI, INC

Tempus AI, Inc. specializes in advanced genomic testing and translational research services for federal health programs, with deep expertise in tumor-normal matched genomic analysis, DNA methylation profiling, and clinical-grade assay development. The company delivers precision medicine capabilities through high-throughput sequencing platforms and bioinformatics pipelines, supporting oncology and chronic disease research initiatives. Their technical proficiency includes molecular diagnostics, biomarker discovery, and data-driven interpretation of genomic alterations in complex patient populations, particularly in HIV+ and veteran cohorts. Tempus AI differentiates itself through end-to-end laboratory execution, from sample processing to clinical reporting, ensuring regulatory-compliant, reproducible results for mission-critical research and care pathways. The contractor maintains a consistent, long-standing relationship with the Department of Veterans Affairs, providing recurring genomic testing services that support personalized treatment decisions for veteran patients. Their work for VA centers on scalable, high-volume molecular diagnostics in oncology, demonstrating reliability in delivering standardized, clinically actionable genomic data under strict federal oversight. A single award from ARPA-H underscores their capacity to support high-risk, high-reward research initiatives requiring agile, contract research organization-level execution in life sciences. Tempus AI’s primary focus lies in medical laboratories (NAICS 621511) and life sciences R&D (NAICS 541715), where they bridge laboratory science with clinical application. Their market positioning centers on precision oncology and epigenetic research, serving government-funded programs that demand rigorous analytical standards and rapid turnaround for patient-centric outcomes. Testing laboratories and services (NAICS 541380) further reflect their operational capacity in assay validation and diagnostic deployment. As a small business structured as a 2L entity based in Chicago, Illinois, Tempus AI operates without federal certifications but maintains a focused government market presence through repeat engagements with VA and ARPA-H. Their geographic footprint is centered on federal health research ecosystems, with a clear emphasis on delivering scalable, science-driven solutions for national health priorities.