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2 Senior Advisors Services for the NINDS Blueprint Neurotherapeutic Network for Small Molecules External Oversight Committee (EOC) Subject Matter Expert (SME) Services

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7571PS27Q00021Federal

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Solicitation 7571PS27Q00021 is a small business set-aside for the National Institute of Neurological Disorders and Stroke to procure two executive-level Senior Advisors to serve as Subject Matter Experts for the Blueprint Neurotherapeutics Network External Oversight Committee. These advisors, who must hold a PhD or MD in Pharmacology, Organic Chemistry, or a related drug development discipline, will provide strategic guidance and technical feedback on drug discovery and development projects within the BPN portfolio. The scope of work includes reviewing program operations, recommending pharmacology-related trial advancements, and participating in monthly virtual meetings and one annual face-to-face meeting at the NIH campus in Bethesda, Maryland. The contract is a Firm-Fixed Price purchase order with a base period from November 5, 2026, to November 4, 2027, and two subsequent one-year option periods. The government anticipates a requirement of 50 labor hours per year per advisor, with an option for an additional 50 hours and annual travel reimbursement up to 2,000 dollars per consultant. Award will be based on best value, with technical personnel qualifications weighted most heavily, followed by price reasonableness and past performance. Proposals are limited to ten pages and must include a completed pricing template, key personnel resumes, and a narrative demonstrating how the proposed experts meet the specific technical requirements.

General Info

Small business set-aside for two PhD/MD Senior Advisors providing drug development strategic guidance.

NAICS

541690 - Other Scientific and Technical Consulting Services

Place of Performance

6138, MD, USA

Set-Aside

SBA

Documents

6

Att 2 Table 12-2 Provisions to Include as Prescribed

PDF, High priority: read this first2 pages · specifications
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Clauses to Include as Prescribed Table

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NIH HEAL Initiative - Technical Evaluation Factors

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RFQ 7571PS27Q00021 - Attachment 4 Pricing Template

XLSX, High priority: read this first1 page · specifications
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SOW - Senior Advisor BPN Small Molecules Pharmacology EOC Support 2026

DOC, High priority: read this first6 pages · sow
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Invoicing Instructions With IPP for Commercial Items

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Timeline

PhaseCombined Synopsis
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AgencyDepartment Of Health And Human Services → Omas Strategic Buying Center - Professional Services
Contacts2 people available
OfficeRockville, MD, 20857, USA

Full Description

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COMBINED SYNOPSIS / SOLICITATION (COMPETITIVE)



Title: 2 Senior Advisors Services for the NINDS Blueprint Neurotherapeutic Network for Small Molecules


External Oversight Committee (EOC) Subject Matter Expert (SME) Services




 (i)           This is a combined synopsis/solicitation for commercial products or commercial services prepared in accordance with RFO Part 12. This announcement constitutes the only solicitation. Offers are being requested and a separate written solicitation will not be issued.



The solicitation number is 7571PS27Q00021 issued as a Request for Quote for 2 Senior Advisors Services for the NINDS Blueprint Neurotherapeutic Network for Small Molecules


External Oversight Committee (EOC) Subject Matter Expert (SME) Services .


The Government reserves the right to make one award, multiple awards, or no awards as a result of this solicitation.



This acquisition is set-aside for small business concerns. This solicitation incorporates provisions and clauses by reference. The full text of provisions and clauses may be accessed electronically at www.acquisition.gov.



The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement.



(ii)           This requirement is for the following services:



The purpose of this requirement is to procure 2 Senior Advisors [subject matter expert (SME) services in support of NIH Blueprint Neurotherapeutics Network drug discovery and development programs and the associated BPN External Oversight Committee.


(iii)          Description of requirement:


The NIH is seeking to procure a highly experienced executive-level, drug discovery and development 2 Senior Advisors with experience in the area of Chemistry and/or Pharmacology to provide feedback to the NIH program leadership and technical guidance on drug discovery and development projects within the BPN portfolio. The Contractor will serve as a member of the BPN External Oversight Committee, which provides strategic guidance on BPN projects and on occasion other NIH drug discovery and development programs.



See Attachment #1 - Statement of Work (SOW) for more information.



(iv)         The Government anticipates award of a Fixed Price purchase order for this acquisition, and the anticipated base period of performance is:



Base:     11/5/2026 – 11/4/2027


Option Year 1: 11/5/2027 – 11/4/2028


Option Year 2: 11/5/2028 – 11/4/2029


               


(v)          The provisions at FAR 52.252-1, Solicitation Provisions Incorporated by Reference (Feb 1998), applies to this acquisition. This solicitation incorporates one or more solicitation provisions by reference, with the same force and effect as if they were given in full text. Upon request, the Contracting Officer will make their full text available. The offeror is cautioned that the listed provisions may include blocks that must be completed by the offeror and submitted with its quotation or offer. In lieu of submitting the full text of those provisions, the offeror may identify the provision by paragraph identifier and provide the appropriate information with its quotation or offer. Also, the full text of a solicitation provision may be accessed electronically at this address: https://www.acquisition.gov/far-overhaul


https://www.hhs.gov/contract-policies-regulations/hhsar-overhaul


(End of provision)


  1. The following FAR provisions are required by FAR 12.2025(a), and incorporated by reference:

  • FAR 52.212-1 (Nov 2025) (RFO Deviation), Instructions to Offerors-Commercial Products and Commercial Services.


  1. The following FAR provisions are required as applicable to this requirement and incorporated by reference:

  • See Attachment 2 for (Table # 12-2) under FAR 12.205 (a)(3).
     

  1. The following HHSAR provisions are applicable to this requirement and incorporated by reference (available upon request):

  • HHSAR 352.239.78 – Information and Communication Technology Accessibility Notice (FEB 2024) (Deviation)


(vi)         The clauses at FAR 52.252-2, Clauses Incorporated by Reference (Feb 1998), applies to this acquisition. This contract incorporates one or more clauses by reference, with the same force and effect as if they were given in full text. Upon request, the Contracting Officer will make their full text available. Also, the full text of a clause may be accessed electronically at this address:


https://www.acquisition.gov/far-overhaul


https://www.hhs.gov/contract-policies-regulations/hhsar-overhaul


(End of clause)



  1. The following FAR clauses are required by FAR 12.205(b)(1) for all solicitations and incorporated by reference:

  • FAR 52.212-4 (Nov 2025) (RFO Deviation), Terms and Conditions—Commercial Products and Commercial Services.


  1. The following FAR clauses are required as applicable to this requirement and incorporated by reference:

  • See Attachment 3: Table# 12-3.
  • FAR 52.232-39, Unenforceability of Unauthorized Obligations (Jun 2013).


The following HHSAR clauses are applicable to this requirement and incorporated by reference:



  • HHSAR 352.204-71, Information and Information System Security (FEB 2024) (Deviation).
  • HSHAR 352-204-73 – Contractor Personnel Security and Agency Access (FEB 2024) (Deviation).
  • HHSAR 352-239-79 – Information and Communication Technology Accessibility (Feb 2024) (Deviation).



FAR/HHSAR PROVISIONS/CLAUSES – FULL TEXT-ADDITIONAL TERMS AND CONDITIONS


The following provisions/clauses and additional terms and conditions apply to this acquisition and are provided in FULL TEXT:



    1. HHSAR 352-237-75 Key Personnel (Oct 2026) (RFO Deviation) - Key personnel specified in this contract are essential to work performance under the contract. The Contractor must obtain the written consent of the Contracting Officer prior to diverting, replacing, or announcing any key personnel substitutions. At least 30 days prior to the Contractor voluntarily diverting any of the specified individuals to other programs or contracts, the Contractor must submit requests for changes in key personnel to the Contracting Officer in writing. The request must identify the circumstances, proposed replacement, a resume and explanation of how the replacement's skills, experience, and credentials meet or exceed the requirements of the contract. When advance notice is not practicable because of termination for cause, other voluntary separation or another circumstance outside the Contractor’s reasonable control, the Contractor must notify the Contracting Officer as soon as practicable.


                     (End of clause)



    1. FAR 52.217-7, Option for Increased Quantity-Separately Priced Line Item (Mar 1989)

The Government may require the delivery of the numbered line item, identified in the Schedule as an option item, in the quantity and at the price stated in the Schedule. The Contracting Officer may exercise the option by written notice to the Contractor within the period of performance of the contract. Delivery of added items shall continue at the same rate that like items are called for under the contract, unless the parties otherwise agree.


(End of clause)



c)  52.217-9 Option to Extend the Term of the Contract.



 (a) The Government may extend the term of this contract by written notice to the Contractor within 15 days of contract expiration; provided that the Government gives the Contractor a preliminary written notice of its intent to extend within the period of performance of the contract. The preliminary notice does not commit the Government to an extension.



(b) If the Government exercises this option, the extended contract shall be considered to include this option clause.



(c) The total duration of this contract, including the exercise of any options under this clause, shall not exceed 3 years.



(End of clause)



TECHNICAL EVALUATION AND INSTRUCTIONS



The Government will evaluate quotations or offers in accordance with RFO FAR 12.203 and award a purchase order from this solicitation to the responsible vendor whose quote conforming to the solicitation will be most advantageous to the Government, price and other factors considered. The factors included in Attachment 5 – Evaluation Factor--shall be used to evaluate quotes: a) Technical capability of the item offered to meet the Government requirement; b) Price; and c) Past performance [see RFO FAR 12.203(a)(2)].



Technical Requirements Instructions:



Responses must include clear and convincing evidence of the Quoter’s capability of fulfilling the requirement as it relates to Technical Factor 1: Personnel Qualifications.



These responses shall include resumes of proposed key personnel, consultants, and any subcontractors, as well as a letter of commitment from proposed key personnel. These responses should also clearly identify whether proposed personnel will be or are an employee of the Quoter. Please note that all proposed key personnel must be employed by the Quoter no later than the start of the contract’s period of performance.



Please note, however, that while resumes of all proposed key personnel are required, they are NOT, by themselves, sufficient. Quoters MUST also submit a separate narrative demonstrating how proposed Key Personnel satisfy the Personnel Qualifications evaluation criteria. Please carefully examine the evaluation criteria prior to writing this narrative.



Business Instructions:



Quoters are required to complete Attachment 4 – Price Template. Quoters are only to fill in the highlighted cells (including the proposed labor rate and the number of consultants being proposed); all other cells will then auto-populate. Quoters must submit the completed pricing template in Excel (do not convert to PDF) as a separate attachment and shall not combine or embed the pricing template with other materials.



Quoters will note that the Government anticipates estimated 50 labor hours per year, with an option for  an up-to-additional 50 hours per year. It should also be noted that the Government may reimburse the successful Quoter(s) for up to $2,000 in annual travel-related expenses, per-consultant, that are necessary for performance of this requirement. These funds shall be provided only after it is determined there is a need for travel. Additionally, all travel requests require advance approval by the Government.



If the Quoter proposes the involvement of any additional staff besides the Key Personnel, it must clearly articulate their role and why it believes additional personnel are necessary to fulfill the requirement. The Quoter must also specify how this time will be charged (e.g. direct hourly rate or included within overhead). Finally, the Quoter is required to document its rationale for any proposed Other Direct Costs (ODCs) besides travel as well as the total amount. If any of these conditions are applicable, the Quoter shall add rows for the additional costs to the Price Template and include a Price Narrative in its response.



Salary Rate Limitation:


Quoters are advised that no NIH funds may be used to pay the direct annual salary of an individual through any contract awarded as a result of this solicitation at a rate in excess of the Executive Schedule, Level II* (direct salary is exclusive of Overhead, Fringe Benefits and General and Administrative expenses, also referred to as "indirect cost" or "facilities and administrative (F&A) costs"). Direct salary has the same meaning as the term "institutional base salary." An individual's direct salary (or institutional base salary) is the annual compensation that the Quoter pays for an individual's appointment whether that individual's time is spent on research, teaching, patient care or other activities. Direct salary (or institutional base salary) excludes any income that an individual may be permitted to earn outside of duties to the Quoter.



This does not preclude Quoters from absorbing that portion of an employee's annual salary (plus the dollar amount for fringe benefits and associated indirect costs) that exceeds a rate of the Executive Schedule, Level II*. The Executive Schedule, Level II* annual salary rate limitation also applies to individuals proposed under subcontracts as well as consultants.



LINK TO EXECUTIVE SCHEDULE RATES OF PAY:


https://www.opm.gov/policy-data-oversight/pay-leave/salaries-wages/ (For current year rates, click on Salaries and Wages/Executive Schedule/Rates of Pay for the Executive Schedule. For prior year rates, click on Salaries and Wages/select Another Year at the top of the page/Executive Schedule/Rates of Pay for the Executive Schedule. Rates are effective January 1 of each calendar year unless otherwise noted.)



Past Performance:


Quoter shall identify 1-2 awards with the Federal Government and/or commercial customers that demonstrate recent and relevant past performance. Relevant is defined as work similar in complexity and magnitude to the work described in the SOW.



Quoter shall include the following information in their past performance examples:


  • Project title
  • Description of the project
  • Contract number
  • Contract amount
  • Government Agency/Organization
  • Point of contact name, address, and phone number
  • Contract and, if applicable, task order number
  • Current status, e.g., completed and/or if in progress, start and estimated completion dates
  • SOW paragraphs that the reference applies to
  • Key personnel (please highlight those individuals who worked on the relevant project(s) and are also being proposed for this effort.)
  • A brief narrative of why you deem the reference to be relevant to this effort


Response Format:


Quoter responses shall be no more than ten (10) single-sided pages in length. This page limit includes the following:



  1. Cover Page, if applicable
  2. Executive Summary, if applicable
  3. Table of Contents, if applicable
  4. Key Personnel Narrative (no more than two pages)
  5. Price Narrative, if applicable
  6. Past Performance Examples


This page limit does NOT include:


  1. Key Personnel Resume(s)
  2. Letter(s) of Commitment
  3. Representations and Certifications
  4. Completed Price Template


Additional Required Information:



In addition to the previously discussed requirements, Quoters must include the following in their response:


  1. Company’s Full Name and Address
  2. Unique Entity ID (UEI)
  3. Name, Telephone Number, and Email Address of Person Authorized to Provide Quote

Please note that, to be considered for award, Quoters must also be actively registered in the System for Award Management (SAM), accessible at www.sam.gov, at the time of quote submission.



  1. Options - The Government will evaluate offers for award purposes by adding the total price for all options to the total price for the basic requirement. The Government may determine that an offer is unacceptable if the option prices are significantly unbalanced. The evaluation of options does not obligate the Government to exercise the option(s).



  1. Notice of award. A written notice of award or acceptance of an offer furnished to the successful Offeror within the time for acceptance specified in the offer, shall result in a binding contract without further action by either party. Before the offer’s specified expiration time, the Government may accept an offer (or part of an offer), whether or not there are negotiations after its receipt, unless a written notice of withdrawal is received before award.

(End of provision)



The following invoice instruction is included and will be incorporated in the final award:


  • Agency Invoicing Instructions (Attachment 6, Invoice Instructions).



(vii)        Quoter must submit all required materials by 1:00 PM Eastern Time on November 5, 2026 and reference solicitation number 7571PS27Q00021 Responses must be submitted electronically to Ebony Chester and Michelle Cecilia, Contracting Office, at contact@example.gov


All questions must be received by November 5, 2026, at 1:00 p.m. EST,  and reference Solicitation Number 7571PS27Q00021.



(viii)       The following additional contract requirement(s) or terms and conditions as determined by the contracting officer are necessary for this acquisition and consistent with customary commercial practices. The associated NAICS code 541690 and the small business size standard is $19 million.  



FAR DEVIATION STATEMENT: “System updates may lag policy updates. The System for Award Management (SAM) may continue to require entities to complete representations based on provisions that are not included in this solicitation. Contracting officers will rely on representations from offers based on provisions in the solicitation. Entities are not required to, nor are they able to, update their entity registration to remove these representations in SAM.”



Responses to this solicitation must include clear and convincing evidence of the offeror’s capability of fulfilling the requirement as it relates to the technical evaluation criteria. The price proposal/quote must include the labor categories, an estimate of the number of hours required for each labor category, fully loaded fixed hourly rate or each labor category, breakdown and rationale for other direct costs or materials, and the total amount.



The Unique Entity ID (UEI) from SAM.gov, the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov.




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