This Solicitation opportunity from Virginia was posted on January 4, 2025. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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2025-073 - Unsolicited PPEA Notice for Hollins Library

Closed

2025-073State & Local

Submission Closed02/25/2025, 12:00:00 AM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541714

New

International

Health & Life Sciences Data ProviderThis subcontract opportunity with the Government of Canada seeks a Health and Life Sciences Data Provider to supply medical datasets and health-related information products. The selected provider will support prime contractors on Public Services and Procurement Canada projects by delivering pharmaceutical data, healthcare statistics, and clinical research information, as well as specialized life sciences reports. Interested parties must be capable of entering into a Provider’s Master License Agreement to facilitate the delivery of these datasets. The solicitation is open for responses until March 31, 2027, with the place of performance located within Canada.

Government of Canada / Gouvernement du Canada

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Senior Advisor for Neurotherapeutic Network (Small Molecules)The Senior Advisor for Neurotherapeutic Network (Small Molecules) is a small business set-aside subcontract through the Department of Health and Human Services Omas Strategic Buying Center. The selected consultant will provide executive-level subject matter expertise to prime contractors supporting NIH NINDS Blueprint Neurotherapeutic Network projects. Primary responsibilities include reviewing program operations, offering strategic recommendations for pharmacology-related trials, and leading drug discovery teams focused on small molecules for nervous system conditions. Qualified candidates must possess a PhD in Pharmacology, an MD, or an advanced degree in Organic Chemistry. The role requires the delivery of high-level technical reports, detailed scientific analyses, and formal recommendations to meet project milestones. This opportunity was posted on October 28, 2026, with a response deadline of November 5, 2026, falling under NAICS code 541714.

Omas Strategic Buying Center - Professional Services

POSTED

DEADLINE

High-throughput Unmasking of Biological Interactomes with Binding Landscape Emulators (HUBBLE)

Solicitation # DARPA-PA-27-01

The High-throughput Unmasking of Biological Interactomes with Binding Landscape Emulators (HUBBLE) program, solicited by the DARPA Biological Technologies Office under DARPA-PA-27-01, seeks to develop an in-silico capability for mapping all protein-protein interactions. The primary objective is to create a comprehensive human interactome hypercatalog capturing over 10 million new interactions, shifting from static biomarkers to dynamic, context-aware interactomes. The utility of this capability will be demonstrated by identifying novel diagnostic and therapeutic targets for traumatic brain injury. Awards will be issued as Other Transaction (OT) for Research agreements with fixed, payable milestones. The program is structured in two phases, with Phase 1 estimated at 12 months and Phase 2 anticipated at 18 months, though current awards are limited to Phase 1. Proposers, including large and small businesses, universities, and research institutions, must submit a maximum six-page unclassified abstract via the Broad Agency Announcement Tool by November 5, 2026, to be considered for an Oral Proposal Package due December 11, 2026. Evaluation is based on technical comprehension, technical ability, and the realism of the cost rough order of magnitude. Prime proposers must be registered in the System for Award Management and demonstrate CMMC Level 1 compliance. Performance will be managed through a Task Description Document and a milestone-based payment schedule, with invoicing processed through the Wide Area Workflow system. Security requirements include the Fundamental Research Risk-Based Security Review Process for all senior and key personnel.

Defense Advanced Research Projects Agcy

POSTED

DEADLINE

Pharmacology and Pain Drug Development SMEThis subcontract opportunity through the Department of Health and Human Services Omas Strategic Buying Center seeks a subject matter expert in pharmacology and pain to support prime contractors on NIH HEAL Initiative projects. The selected expert will provide executive-level guidance on small molecule and biologic therapeutics, focusing on drug discovery and pharmacology-related trials for nervous system conditions. Key responsibilities include performing strategic programmatic reviews, evaluating milestones, and providing mentorship. The role requires the delivery of strategic recommendations and milestone evaluations through formal committee reports. Performance will take place in Bethesda, and the opportunity is categorized under NAICS code 541714. Interested parties should note the response deadline of November 3, 2026.

Omas Strategic Buying Center - Professional Services

POSTED

DEADLINE

Precision Prevention & Biological Pathway ResearchThe Precision Prevention and Biological Pathway Research subcontract supports prime contractors on Defense Health Agency Alzheimer’s Research Program projects. The primary objective is to conduct research linking service-related exposures to AD/ADRD biological pathways by quantifying military-relevant risk factors. This technical work involves the use of proteomics tools and genomic sequencing to map these biological pathways, culminating in the delivery of detailed research reports and data. Performance of this contract takes place in Frederick, Maryland, under NAICS code 541714. Due to the nature of the study, the contractor must obtain IRB approval and maintain all necessary Human Subjects Research certifications. Interested parties should note the response deadline of December 4, 2026.

Defense Health Agency

POSTED

DEADLINE

Blood-Based Biomarker Validation & ScalingThis subcontract focuses on the validation and scaling of blood-based biomarkers to support prime contractors within the Defense Health Agency Alzheimer’s Research Program. The scope of work involves performing detailed laboratory analysis of blood samples, validating the sensitivity and specificity of assays, and establishing scalable testing protocols. These operations must utilize Simoa equipment and biobanking systems while adhering strictly to GLP standards and maintaining CLIA certification. The project is managed under the Department of Defense and is centered in Frederick, Maryland. The primary objective is the delivery of validated, scalable biomarker assays and protocols to advance research goals. Interested parties should note the response deadline of December 4, 2026, and the classification of the work under NAICS code 541714.

Defense Health Agency

POSTED

DEADLINE

RFI Alzheimer’s Research Program (AZRP) Public

Solicitation # HT9427RFI2027AZRP

The Defense Health Agency, through the Congressionally Directed Medical Research Programs, has issued a Request for Information under solicitation number HT9427RFI2027AZRP to gather strategic feedback for the fiscal year 2027 Alzheimer’s Research Program. The primary objective is to identify research focus areas and funding opportunities aimed at mitigating the impact of Alzheimer's and related dementias, specifically those associated with traumatic brain injury, military service, and diverse risks. The program seeks to improve the quality of life for Service Members, Veterans, and their families by funding solution-oriented research, including the development of digital and blood-based biomarkers for early diagnosis and the creation of precision prevention strategies. This action is strictly for information and planning purposes and does not constitute a formal solicitation, request for proposals, or request for quotations. No contracts will be awarded based on this announcement, and FY27 funds have not yet been appropriated. Interested parties from academia, industry, non-profit organizations, and federal agencies are invited to provide feedback via Survey Monkey by December 4, 2026. Respondents are cautioned not to submit proprietary or sensitive information through the survey portal as it cannot be protected. The effort is categorized under NAICS code 541714 and is managed by the Department of Defense in Fort Detrick, Maryland.

Defense Health Agency

POSTED

DEADLINE

Traumatic Brain Injury and Psychological Health Research Program Public Request for Information

Solicitation # HT9427RFI2027TBIPHRP

The Defense Health Agency, under the Department of Defense and the Congressionally Directed Medical Research Programs, has issued a Request for Information under solicitation number HT9427RFI2027TBIPHRP. This action is strictly for strategic planning and is not a formal solicitation, request for proposals, or request for quotations. The primary objective is to gather feedback from academia, industry, non-profit organizations, and the public to inform the research focus areas and funding opportunities for the fiscal year 2027 Traumatic Brain Injury and Psychological Health Research Program. The program aims to optimize the prevention, assessment, and treatment of psychological health conditions and traumatic brain injuries to benefit Service Members, Veterans, and the general public. Interested parties are asked to provide input on research gaps and funding priorities, specifically regarding the prevention, screening, diagnosis, and treatment of these conditions. Responses must be submitted via Survey Monkey by December 11, 2026. Because the government cannot protect proprietary or sensitive information submitted through the survey platform, such data should not be included. This inquiry does not commit the program to incorporating the feedback into future funding opportunities, and no contract will be awarded based on this specific announcement. All inquiries regarding this RFI should be directed to Patrick M. Younkins.

Defense Health Agency

POSTED

DEADLINE

Request for Proposals (RFP) - BARDA Vaccine Medical Countermeasures for Pandemic Influenza Preparedness & Response

Solicitation # 75A50126R00001_RFP_NPIVS_27

The Biomedical Advanced Research and Development Authority (BARDA) is soliciting proposals for the Vaccine Medical Countermeasures for Pandemic Influenza Preparedness and Response Program. The objective is to maintain a permanent readiness posture against high-threat influenza and other viruses with pandemic potential. Selected contractors will provide essential services, personnel, and facilities to produce vaccines, antigens, and adjuvants, while generating the necessary analytical, nonclinical, clinical, and chemistry, manufacturing, and controls data for FDA submission to support rapid regulatory decisions. To be eligible, offerors must be capable of producing vaccines against influenza strains with pandemic potential and demonstrate success through a U.S. influenza vaccine license or a submitted Biologics License Application. The government intends to award contracts to four offerors based on the Highest Technically Rated Offerors with a Fair and Reasonable Price methodology. Evaluation focuses on capabilities, past performance, and price, with a minimum requirement of a High Confidence rating for technical capabilities. The contract structure consists of a 60-month base period and a 60-month option period, with a minimum guarantee of 50,000 dollars. Key requirements include the development of comprehensive manufacturing and business continuity plans, adherence to strict ASPR security and cybersecurity standards, and the use of the Department of Treasury Invoice Processing Platform for quarterly invoicing. Performance is monitored through a BARDA dose tracker, and final acceptance is triggered by the submission of a final report and updated dose tracking data.

Barda - Aspr / Daappo / Barda Dcma

POSTED

DEADLINE

USDA SBIR/STTR Topic 8.2 — Plant Production and Protection - Biology

Solicitation # USDA-NIFA-TOPIC-8.2

The USDA National Institute of Food and Agriculture is soliciting proposals under Topic 8.2 for Plant Production and Protection - Biology. This initiative focuses on advancing crop production and protection through the development of innovative plant breeding methods, diagnostic technologies for diseases, and the creation of new food and non-food crop plants. Research efforts are directed toward improving plant characteristics to mitigate biotic and abiotic stresses, developing new genotypes for commercial applications, and creating tools to support the health of natural and domesticated pollinators. This opportunity is a total small business set-aside under the SBIR/STTR mandate, restricting eligibility to companies with fewer than 500 employees. Managed by the United States Department of Agriculture, the program is led by Dr. Christopher Philips. Interested parties can find further details and application guidelines through the NIFA website.

National Institute of Food and Agriculture

POSTED

DEADLINE

Quantitative Analysis of Longitudinal MR Images

Solicitation # 75N98027R00005

Solicitation 75N98027R00005 is a Sources Sought notice issued by the National Institute on Aging (NIA) to identify qualified companies capable of performing quantitative analysis of longitudinal Magnetic Resonance (MR) images. The project supports the Baltimore Longitudinal Study of Aging (BLSA) by processing 300 newly acquired MR datasets to characterize brain aging trajectories and identify predictors of cognitive decline and Alzheimer’s disease. The selected contractor will provide specialized, non-commercial services to deliver global and regional tissue volumes, lesion quantification, and machine learning-derived scores, such as SPARE-AD, while ensuring longitudinal consistency with data acquired since 1994. The anticipated contract will be a firm fixed price award with a period of performance of one year. Key deliverables include quantitative volumetric results, intermediate processing files, and registration maps for PET overlay, submitted every six months, concluding with a final report. Technical requirements emphasize the use of established image analysis tools and adherence to FISMA/FedRAMP-aligned data security controls to protect participant confidentiality. Interested respondents must submit a capability statement by November 9, 2026, to Contract Specialist Sneha Singh. The submission must be limited to ten pages and include the company's Unique Entity ID, NAICS code 541714, professional qualifications of personnel, and any applicable GSA schedules or government-wide acquisition contracts. Small businesses are encouraged to respond to this market research effort to help the government determine the appropriate acquisition method.

National Institutes Of Health Olao

POSTED

DEADLINE

Q--AMPLICON SEQUENCING SERVICES

Solicitation # 140G0226Q0047

The Department of the Interior, through the USGS OAG Denver Acquisition Branch, is soliciting quotations for a Blanket Purchase Agreement (BPA) to provide next-generation amplicon sequencing services for the Michigan Bacteriological Research Laboratory. The agreement has a not-to-exceed value of $250,000 over a five-year period of performance from September 17, 2026, to September 16, 2031. The scope of work includes non-personal services such as library preparation for 16S V4 amplicon sequencing, library pooling, and sequencing using Illumina MiSeq or AVITI platforms to support research on bacterial pathogens, antibiotic resistance, and microbial ecology. Key deliverables include demultiplexed raw data and reporting metrics, with a required delivery turnaround of 60 business days from sample receipt. Award decisions will be based on technical and priced factors, with non-priced factors carrying significantly more weight. Technical evaluations will focus on the contractor's on-site equipment, personnel experience, quality control procedures, business establishment, and a capabilities narrative. Offerors must also provide two customer references from the last five years. The contract is subject to various federal regulations, including specific security prohibitions regarding certain telecommunications equipment and the requirement for electronic invoicing through the Invoice Processing Platform System. Quotations are due by November 5, 2026, and must be submitted via email to the primary point of contact.

Ofc Of Acquisition Grants-Denver

POSTED

6 days ago

DEADLINE

in 8 days

General Info

Agency

Virginia → Roanoke County

NAICS

541714 - Research and Development in Biotechnology (except Nanobiotechnology)

Place of Performance

VA, USA

Set-Aside

NONE

Documents

Roanoke County PPEA Procedures April 2003 (rev. Jan. 2021)

26 pages · procedures

High

Unsolicited PPEA Proposal for Roanoke County Public Library - Hollins Branch

ppea-proposal

High

2025-073 Unsolicited PPEA Notice for Hollins Library

unsolicited-ppea-notice

Low

AI Contract Breakdown

Uniform Contract Format

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Timeline

PhaseClosed

PostedJan 4

Solicitation

Response DeadlineFeb 25

Deadline has passed

Submission Closed

02/25/2025, 12:00:00 AM UTC

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Organization & Contact Information

AgencyVirginia → Roanoke County

ContactsNo contacts available

OfficeN/A

Organization / AgencyVirginia → Roanoke County

Office AddressN/A

ContactsNo contact information available

Full Description

PUBLIC NOTICE OF RECEIPT OF AN UNSOLICITED PPEA PROPOSALThe Board of Supervisors of Roanoke County, Virginia, has accepted a proposal for review from G&H Contracting, Inc. for the Hollins Library redevelopment project located at 6624 Peters Creek Road, Roanoke, VA, in accordance with the Public Private Educational Facilities and Infrastructure Act of 2002 (“PPEA”), as set forth in Chapter 22.1, Title 56 of the Code of Virginia, 1950, as amended, and the County's PPEA guidelines (the Guidelines) which have been adopted pursuant to the Act. Roanoke County intends to evaluate the proposal, may negotiate an interim or comprehensive agreement with the proposer based on the proposal, and will accept for simultaneous consideration any competing proposals that comply with the PPEA and the Guidelines.Proposers shall provide a processing fee check in the amount of $5,000 payable to the Treasurer of Roanoke County with their proposal submissions. The proposal and processing fee must be submitted to:Heath Honaker, Purchasing Division DirectorCounty of Roanoke5204 Bernard Drive SWSuite 300-FRoanoke, VA 24018In order to be considered, all proposals must be submitted in a sealed envelope/package and received in the Roanoke County Finance Department Purchasing Division, located at the address above, no later than 5:00 p.m. (local prevailing time) on Tuesday, February 25, 2025. Any private entity submitting a competing proposal shall submit in a sealed envelope/package one (1) original and seven (7) copies and one (1) redacted copy of its proposal fit for public dissemination in the event the County must respond to a Freedom of Information Act request. The redacted copy of Offeror's proposal shall be provided on a USB Drive or other electronically transferable media. It shall be redacted to protect confidential and/or proprietary information and be labeled as such. Copies of the non-proprietary sections of the G&H Contracting, Inc. proposal may be viewed and/or downloaded from either the County Website/eVA via the links below: Roanoke County: https://www.roanokecountyva.gov/Bids.aspx?CatID=100&txtSort=BidNumberAsc&showAllBids=on&Status=eVA: https://mvendor.cgieva.com/Vendor/public/AllOpportunities.jsp?status=Open&agencyname=County%20of%20Roanoke. ;The Roanoke County PPEA procedures are available on the County Website - https://www.roanokecountyva.gov/DocumentCenter/View/30880/Roanoke-County-PPEA-ProceduresConceptual design drawings and programming documents will be made available upon request of a Proposer.A copy is also available for public inspection in the Purchasing Office on the 3rd floor of the County Administration Center, 5204 Bernard Drive, Roanoke, VA, 24018. Roanoke County solicits participation from minority-owned businesses.

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