66 -- Pulse X-Ray Instrument
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The National Heart, Lung, and Blood Institute (NHLBI) is seeking to develop an advanced X-ray based structural biology program that utilizes a near-monochromatic pulsed X-ray source with highly specific technical parameters. The desired instrument should achieve a peak flux of 10^10 photons per pulse, operate at a repetition rate between 1 and 10 Hz with future scalability to 1 kHz, and maintain an average flux ranging from 10^11 to 10^13 photons per second. Additional specifications include a peak brilliance of 10^23 photons per second per square millimeter per milliradian squared within a 1% bandwidth, a wavelength range from 0.4 to 45 angstroms, an energy range of 0.28 to 30 keV, and a pulse width under 10 picoseconds. The source is expected to have a size smaller than 20 micrometers, less than 2 milliradians divergence, partial transverse coherence, and tunability across repetition rate, bandwidth, and wavelength. The suggested dimensions for the device are approximately 3 by 5 by 1.5 meters. NHLBI is consulting with industry leaders to evaluate the feasibility and potential for collaboration in building such a device, aiming to push the state-of-the-art in monochromatic X-ray sources. Comments regarding the achievability or possible exceeding of the proposed specifications are invited, with a formal request for proposals planned for fiscal year 2006. An industry meeting will be held before October 1, 2005, to discuss possible approaches. Interested parties are asked to submit contact information along with any questions or comments by August 31, 2005, to the NHLBI Contracts Operations Branch, specifically to Ms. Debra C. Hawkins, with responses accepted via written or electronic means.
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