A collection of 128 human pluripotent stem cell lines

This modification does the following: 1. Incorporates and requires completion of FAR Provision 52.204-24 2. Replaces FAR Clause 52.212-5 3. Extends the quotation due date (i) This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. (ii) The solicitation number is 75N95019Q00297 and the solicitation is issued as a request for quotation (RFQ). This acquisition is for a commercial item and is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13 - Simplified Acquisition Procedures and FAR Part 12 - Acquisition of Commercial Items, and is not expected to exceed the simplified acquisition threshold. THIS IS A NON-COMPETITIVE (NOTICE OF INTENT) COMBINED SYNOPSIS SOLICITATION TO AWARD A CONTRACT OR PURCHASE ORDER WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME). The National Institutes of Health (NIH) intends to negotiate and award a purchase order without providing for full and open competition (Including brand-name) to WiCell Research Institute, Inc., at 504 S. Rosa Road, Suite 101, Madison, WI 53719. This acquisition is conducted as non-competitive for a commercial service and is conducted under the authority of the FAR Part 13 - Simplified Acquisition Procedures, and FAR 13.106-1(b) - Soliciting from a single source. The determination by the Government to award a contract without providing for full and open competition is based upon the market research conducted that produced no other sources capable of providing this Government requirement due to the need for continuity of science. (iii) The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2019-04, effective August 7, 2019. (iv) The associated NAICS code is 621991 and the small business size standard is $32.5M. DESCRIPTION (v) The National Center for Advancing Translational Sciences (NCATS) at the National Institutes of Health (NIH) requires a collection of 128 human pluripotent stem cell lines to meet project milestones in support of the Helping to End Addiction Long-term (HEAL) Initiative. See attached for the list of 128 cell lines. All cell lines must undergo the following tests prior to shipment to ensure genomic integrity, correct identity and sterility of the cellular material, meeting the NIH rigor and reproducibility guidelines. The Contractor must provide a detailed report containing the results of quality control testing for each cell line provided to NCATS. A. Thaw recovery: must be equal to or greater than 60%. B. Identity by short tandem repeat analysis: each cell line's STR profile must match the profile of the original deposited material. C. Mycoplasma contamination screening: must be negative and free of mycoplasmal contamination. D. Sterility testing: must be free of bacterial and viral contamination. E. G-banded karyotyping: must be normal at a typical G-banded karyotype resolution. The cell lines that fail to display a normal karyotype will be replaced by another qualifying cell line of the recipient scientist's choosing, alternatively, the recipient scientist may choose to retain the cell line for the purpose of comparison between normal and abnormal lines. If any of the cell lines fail quality control testing, the Contractor will notify NCATS and NCATS will decide whether to accept the line. If NCATS does not accept the line, or if a cell line is otherwise unavailable, NCATS will choose a replacement line or will approve of the Contractor's suggested replacement line. (vi) The required quantity is two (2) vials per line. (vii) Delivery is to occur within 45 days after receipt of order. The cell lines are to be shipped in a "vapor shipper", a container with a small amount of liquid nitrogen, encased in a secure secondary container. This allows for a constant low temperature during transport. (viii) The anticipated award date is August 23, 2019. EVALUATION (ix) The Government plans to award a contract resulting from this solicitation. The award will be made to the responsible offeror whose offer is most advantageous to the Government, price and other factors considered. The following factors shall be used to evaluate quotations: Technical Capability, Past Performance, and Price. Comparative evaluations will be conducted in the event that multiple quotations are received. VENDOR AND SUBMISSION REQUIREMENTS (x) Offerors must have an active registration in the System for Award Management (SAM) www.sam.gov. (xi) Responses to this solicitation must include sufficient information to establish the interested parties' bona-fide capabilities of performing the required service. Responses must also include the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. Responses must also include the completed representation in the provision at FAR 52.204-25 (Aug 2019), which is attached. (xii) The price quote must include the unit price, total price, shipping and handling price, prompt payment discount terms, product or catalog number(s), product/services description, and any other information or factors that may be considered in the award decision. (xiii) All responses must be received by 11:59am EDT on August 21, 2019, and reference solicitation number 75N95019Q00297. Responses must be submitted via email to Kimberly Espinosa, Contract Specialist, at kimberly.espinosa@nih.gov, with a copy to Jeff Schmidt, Contracting Officer, at Jeffrey.schmidt@nih.gov. (xiv) For information regarding the solicitation, contact Kimberly Espinosa, Contract Specialist, at 301-827-3546 or kimberly.espinosa@nih.gov. (xv) All responsible sources may submit a bid, proposal, or quotation which shall be considered by the agency. PROVISIONS AND CLAUSES (xvi) The provision at FAR 52.252-1, Solicitation Provisions Incorporated by Reference (Feb 1998). This solicitation incorporates one or more solicitation provisions by reference, with the same force and effect as if they were given in full text. Upon request, the Contracting Officer will make their full text available. The offeror is cautioned that the listed provisions may include blocks that must be completed by the offeror and submitted with its quotation or offer. In lieu of submitting the full text of those provisions, the offeror may identify the provision by paragraph identifier and provide the appropriate information with its quotation or offer. Also, the full text of a solicitation provision may be accessed electronically at www.acquisition.gov. The following provisions apply to this acquisition and are incorporated by reference: - The provision at FAR 52.204-7, System for Award Management (Oct 2018) - The provision at FAR 52.204-16, Commercial and Government Entity Code Reporting (Jul 2016) - The provision at FAR 52.212-1, Instructions to Offerors - Commercial Items (Oct 2018) - The provision at 52.212-3, Offeror Representations and Certifications-Commercial Items (Oct 2018) (xvii) The clause at FAR 52.252-2, Clauses Incorporated by Reference (Feb 1998). This contract incorporates one or more clauses by reference, with the same force and effect as if they were given in full text. Upon request, the Contracting Officer will make their full text available. Also, the full text of a clause may be accessed electronically at www.acquisition.gov. In addition to the clauses checked in FAR 52.212-5 (attached), the following clauses also apply to this acquisition and are incorporated by reference: - The clause at FAR 52.204-13, System for Award Management Maintenance (Oct 2018) - The clause at FAR 52.204-18, Commercial and Government Entity Code Maintenance (Jul 2016) - The clause at FAR 52.212-4, Contract Terms and Conditions - Commercial Items (Oct 2018) - The clause at HHSAR 352.222-70, Contractor Cooperation in Equal Employement Opportunity Investigations (December 18, 2015) (xviii) There are no additional contract requirement(s) or terms and conditions applicable to this acquisition. (xix) The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement. (xx) The following provisions and clauses apply to this acquisition and are attached in full text: - The provision at FAR 52.204-24, Representation Regarding Certain Telecommunications and Video Surveillance Services or Equipment (Aug 2019) - Addendum to the clause at FAR 52.212-4, Contract Terms and Conditions - Commercial Items (Oct 2018) - The clause at FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders-Commercial Items (Aug 2019) - NIH Invoice and Payment Provisions (2/2014)