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Somatic Mosaicism across Human Tissues (SMaHT) Program: Tissue Procurement Center (R24 Clinical Trial Not Allowed)

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Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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The National Institutes of Health is seeking a Tissue Procurement Center to support the Somatic Mosaicism across Human Tissues (SMaHT) Network. The primary goal of this initiative is to advance the understanding of biological processes and disease mechanisms driven by somatic mutations in human tissues. The center will be responsible for the collection, processing, storage, and distribution of high-quality human tissue specimens to enable functional analyses and the characterization of somatic mosaicism. The program aims to expand its existing foundation of 150 healthy donors by procuring tissues from at least 50 additional healthy individuals, reaching a total of 200. Additionally, the center will collect up to 10 special tissue cohorts, which may include clinically relevant samples, tissues suitable for culture, or organs requiring specialized handling. The awardee will collaborate with other SMaHT Stage 2 initiatives to ensure that all samples are sufficient for production-level assays.

General Info

NIH seeks a center to procure, store, and distribute human tissue specimens.

Agency

Department Of Health And Human Services → National Institutes Of Health

NAICS

621991 - Blood and Organ Banks

Place of Performance

Not specified

Set-Aside

NONE

Documents

0

No documents available

Documents will appear here when they are available.

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeUSA
Organization / AgencyDepartment Of Health And Human Services → National Institutes Of Health
Office AddressUSA
Contacts
SMaHT Program
contact@example.gov

Full Description

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The purpose of the Somatic Mosaicism across Human Tissues (SMaHT) Network is to advance the discovery of biological processes and disease mechanisms mediated by somatic mutations in human tissues. 

Since 2023, the program has generated multi-omic somatic mutation datasets from a standardized set of human tissues spanning all three germ layers. Building on the Stage 1 foundation, the NIH intends to issue a Notice of Funding Opportunity (NOFO) seeking support for the SMaHT Tissue Procurement Center (TPC) initiative.  

The TPC will enable functional analyses of these healthy and clinically relevant tissue samples, providing critical resources to support characterization of somatic mosaicism and its role in human biology and disease. The Tissue Procurement Center will support the Network by collecting, processing, storing, and rapidly distributing high-quality, well-characterized human tissue specimens. Building on the 150 healthy donors enrolled during Stage 1, the TPC will procure tissues from at least 50 additional healthy donors, bringing the total to 200. The TPC will also collect up to 10 special tissue cohorts. The special tissue cohorts may include: tissues that can be grown in culture, tissues that are of high interest for somatic mosaicism studies, clinically relevant samples, organs that require special handling procedures, and other relevant samples. Awardee will collaborate with other SMaHT Stage 2 initiatives to ensure that the samples are sufficient and useful for running production level assays within the program. 

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Earlier notices in this NAICS code

Posted before this notice, open and closed

NAICS: 621991
Federal
Blood Samples
AD for Laboratory Programs

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DEADLINE

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NAICS: 621991
Grant
Limited Competition: Biospecimen Banks to support NCI National Clinical Trials Network Biospecimen Banks (NCTN Biobanks) and the NCI Early-Phase and Experimental Clinical Trials Biospecimen Bank (EET Biobank) (U24 Clinical Trial Not Allowed)
Solicitation # RFA-CA-28-004
National Institutes Of Health

POSTED

10 months ago

DEADLINE

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View Details
NAICS: 621991
Grant
Notice of Intent to Publish a Funding Opportunity Announcement for Single Source for Continuation of the Integrated Islet Distribution Program (UC4)
Solicitation # RFA-DK-27-147
National Institutes Of Health

POSTED

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NAICS: 621991
Federal
Oklahoma Blood Institute
Indian Health Service

POSTED

almost 57 years ago

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N/A
View Details
NAICS: 621991
Federal
Cord Blood Center 5 (Duke)
Health Resources And Services Administration

POSTED

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N/A
View Details
NAICS: 621991
Federal
Lab Supplies
Indian Health Service

POSTED

almost 57 years ago

DEADLINE

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NAICS: 621991
Federal
The Procurement of a supply of Whole Blood and Apheresis Platelets for Research
Food And Drug Administration

POSTED

almost 57 years ago

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View Details
NAICS: 621991
Federal
Commodities
Indian Health Service

POSTED

almost 57 years ago

DEADLINE

N/A
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NAICS: 621991
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Blood Products
Indian Health Service

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NAICS: 621991
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Cord Blood Center 1 (Life South)
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