Continuation and Expansion of the National Mesothelioma Virtual Bank for Translational Research (U24)
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The National Mesothelioma Virtual Bank, managed by the Centers for Disease Control and Prevention under the Department of Health and Human Services, is a translational research initiative focused on advancing biomedical research for malignant mesothelioma. This forecast opportunity aims to expand the existing virtual registry and tissue bank by integrating additional biospecimens, such as frozen tumor tissues, blood, DNA, and protein samples, with comprehensive demographic and clinical data. By providing a shared repository of genomic, transcriptomic, and proteomic data, the project supports the identification of early disease signs, the development of prognostic biomarkers, and the creation of improved treatment options. The primary objective is to enhance the bank's capacity as a critical resource for the clinical science community and biomedical researchers. This effort is categorized under NAICS code 621991 and is designed to facilitate the sharing of high-quality specimens and data to accelerate breakthroughs in mesothelioma research.
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Full Description
The National Mesothelioma Virtual Bank (NMVB) was established in 2006 to serve as a resource for malignant mesothelioma research. This funding opportunity will advance biomedical research for malignant mesothelioma by adding more biospecimens together with demographic data and clinical data.
Examples of biospecimens include fresh frozen tumor and control tissues, paraffin embedded tissues, blood, DNA, RNA, and protein samples from mesothelioma patients. Demographic data includes age, sex, race, and occupational history. Clinical data includes stage, treatment, and survival information.
The virtual registry and tissue bank also serve as a virtual repository and offer a library of biospecimens and data that investigators can use and share, including genomic, transcriptomic, and proteomic data.
The NMVB can:
- Help identify early signs of disease.
- Support the development of biomarkers that show disease stage and prognosis.
- Help develop new or improved treatment options.
The goal is to continue to expand the NMVB and improve its ability to be a resource for both biomedical researchers and the clinical science community focused on malignant mesothelioma research.
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