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NIOSH Centers of Excellence for Total Worker Health® (U19)

Active
Grant

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

AI Contract Overview

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The NIOSH Centers of Excellence in Total Worker Health program aims to support research and translation activities focused on preventing harmful exposures, improving working conditions, and advancing worker well-being. Priority areas include high-risk occupations such as first responders and vehicle mechanics, young workers, small to medium enterprises, chronic disease, mental health, substance use disorders, and the application of artificial intelligence and digital technologies. All projects must utilize the NIOSH Worker Well-Being Questionnaire and share data with the HERO Worker Well-Being Clearinghouse. The funding structure is divided into several required components, including an overall leadership component, an administration and evaluation core, and an outreach and dissemination core. Research activities comprise the bulk of the budget and must include at least one small research project for exploratory or early-stage studies and at least one large research project for multiyear translational or mechanistic studies, the latter of which requires an economic evaluation. An optional pilot program is also available for short-term studies involving preliminary data or digital technology approaches.

General Info

NIOSH funds Centers of Excellence for Total Worker Health® with mandatory research, data sharing, and budget allocations focused on high-risk workers and well-being.

Agency

Department Of Health And Human Services → Centers For Disease Control And PreventionView Agency

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)View NAICS

Place of Performance

Not specified

Set-Aside

NONE

Documents

(0)

No documents available

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Timeline

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → Centers For Disease Control And Prevention
Contacts1 person available
OfficeUSA
Organization / Agency
Department Of Health And Human Services → Centers For Disease Control And Prevention
View Agency Profile
Office AddressUSA
Contacts
Maria Lioce Scientific Program Official
contact@example.gov
+1 (555) 000-0000

Full Description

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PURPOSE
NIOSH intends to support the Centers of Excellence in Total Worker Health® (TWH). These Centers will conduct rigorous research and translation activities to prevent harmful exposures, improve working conditions, and advance worker well-being. The Centers will develop practical, scalable solutions for employers and workers. All projects must use the NIOSH Worker Well-Being Questionnaire (WellBQ) and share data with the HERO Worker Well-Being Clearinghouse. Large Research Projects require economic evaluation. 

PRIORITY AREAS
• High-risk occupations: First responders, vehicle mechanics, and technicians, with emphasis on occupational exposures, related health risks, and prevention strategies
• Young workers, SMEs 
• Chronic disease
• Mental health, stress
• Substance use disorder
• Artificial intelligence (AI), digital technologies

This is a multi-component NOFO.

COMPONENT STRUCTURE
Percentages indicate maximum share of total budget.

Overall Component (Required)
Provides Center leadership and integration. Applicants should show strong coordination, scientific direction, and alignment across projects.

Administration, Evaluation, and Emerging Issues Core (Required; up to 15%)
Supports management and Center-wide evaluation. Applicants should describe oversight, data governance, and quality assurance.Optional activities include emerging issues and shared research resources.

Outreach, Dissemination, and Impact Core (Required; up to 15%)
Supports communication, worker/employer engagement, training, translation, implementation, and dissemination strategies.

Research Projects (Required; about 60 to 70%)
Includes all research activities. Applicants may propose a mix of projects. Research project distinctions are based on scope and complexity rather than cost. Projects should demonstrate scientific rigor and potential for sustained impact.

  • Small Research Projects (Required; at least one project; up to 3 years)
    Exploratory, feasibility, early-stage intervention, surveillance, or measurement studies.
    Priority areas: high-risk occupations, young workers, SMEs.
    Should show innovation and potential to expand. 
  • Large Research Projects (Required; at least one project; up to 5 years)
    Multiyear etiologic, mechanistic, intervention, or translational studies.
    Priority areas: chronic disease, mental health, substance use disorder. 
    Economic evaluation is required. Projects should include strong design and analytic plans. 
  • Pilot/Feasibility Program (Optional; 12–18 months) 
    Short-term studies generating preliminary data or testing AI/digital technology approaches.

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