Expanded Surveillance for Pediatric Infectious Diseases
Contract Overview
Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.
AI Contract Overview
This Notice of Funding Opportunity from the Centers for Disease Control and Prevention seeks to establish a network of U.S. institutions to conduct standardized, prospective surveillance of pediatric acute respiratory illness and acute gastroenteritis. The primary goal is to monitor respiratory and enteric viruses among pediatric patients to generate effectiveness estimates for prevention products, such as vaccines for influenza, rotavirus, and RSV, while analyzing hospitalization rates and the natural history of these diseases. Applicants must apply for the required Core Component, which focuses on inpatient and emergency department surveillance following CDC protocols. Additionally, institutions may apply for optional components involving outpatient surveillance or studies on immune responses related to infection and immunization. The ultimate objective of this initiative is to improve diagnostic and treatment protocols, inform public health strategies, and reduce healthcare utilization and hospitalizations among children.
General Info
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Full Description
The purpose of this Notice of Funding Opportunity (NOFO) is to support a network of U.S. institutions that will conduct standardized, prospective, active surveillance of pediatric acute respiratory illness (ARI) and acute gastroenteritis (AGE). The network will focus on respiratory and enteric viruses among pediatric patients seeking healthcare.
In addition, the network will generate robust estimates of the effectiveness of influenza, rotavirus, respiratory syncytial virus (RSV) and other prevention products against respiratory and enteric viral illnesses in this population.
Recipients will identify AGE and ARI illnesses among patients seeking healthcare or diagnostic testing for acute illness among inpatient and emergency department populations. Recipients may also include patients seeking care in outpatient clinics, such as urgent care centers, as an optional activity.
This is a multi-component NOFO. You must apply for ComponentA (Core Component). You may also apply for one or more optional components.
Component A – Core Component (Required)
- Support inpatient and emergency department pediatric surveillance
- Follow the standardized protocol established by CDC
Optional Components
- Component B: Support outpatient pediatric surveillance
- Component C: Study immune response and infection
- Component D: Study immune response and immunization
Recipients will enroll patients meeting standard symptom criteria and confirm viral infections using approved molecular assays. The network will use the data to estimate prevention product effectiveness, hospitalization rates, and information on the natural history of medically attended diseases.
Findings of this NOFO will:
- Improve best practices for diagnosis and treatment protocols
- Inform prevention product recommendations
- Guide public health strategies
- Reduce viral illness-associated hospitalizations and healthcare utilization among children
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