INCLUDE Project: Omics Phenotypes Related to Down Syndrome (X01 Clinical Trial Not Allowed)
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The National Institutes of Health is soliciting applications through the INCLUDE Project to generate integrated genomic and multi-omics data to better understand the molecular mechanisms of health conditions associated with Down syndrome. This initiative focuses on utilizing existing biospecimens from individuals with Down syndrome and control groups to produce data that will be integrated into the INCLUDE Data Hub for use by the broader research community. This opportunity is categorized as a forecast and is managed by the Department of Health and Human Services. It is important to note that no direct funding will be provided to applicants under this specific notice; instead, the project seeks the submission of samples to NIH supported resources to facilitate the discovery of omics phenotypes.
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The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. The purpose of this Notice of Funding Opportunity (NOFO) is to solicit applications to submit samples to NIH INCLUDE Project-supported resources to generate a large volume of integrated genomic and multi-omics data that will facilitate discovery of the molecular mechanisms of health conditions related to Down syndrome. The resulting data, and associated clinical and phenotypic data, will become part of the INCLUDE Data Hub for sharing with the research community. No funding will be provided directly to applicants under this NOFO. Applicants are encouraged to propose omics assays of existing biospecimens collected from individuals with Down syndrome and controls.
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