A -- Phase I Clinical Studies of New Chemopreventive Agents

Division of Cancer Prevention (DCP), National Cancer Institute (NCI), National Institute of Health (NIH), intends to award up to five contracts under the existing Master Agreement (MA) pool for "Phase I Clinical Trials of New Chemopreventive Agents." The RFP consists of four workstatements (Nos. 41 through 44) as follows: No. 41-Phase I Single and Multiple-Dose Safety and Pharmacokinetics Clinical Study of Resveratrol; No. 42-Phase I Single and Multiple-Dose Safety and Pharmacokinetics Clinical Study of Bowman-Birk Inhibitor Concentrate (2 awards possible); No. 43-Phase I Single and Multiple-Dose Safety, Pharmacokinetics, and Drug Interaction Clinical Study of Polyphenon E; and No.44-In Vivo and In Vitro Pharmacology of a Chemopreventive Agent in Subjects with Basal Cell Nevus Syndrome. The North American Industry Classification System (NAICS) for this project is 541710. AN AWARD WILL ONLY BE MADE TO A MASTER AGREEMENT HOLDER IN THE PHASE I CLINICAL TRIALS OF NEW CHEMOPREVENTIVE AGENTS MASTER AGREEMENT POOL. Those who are not currently in the Phase I Clinical Trials of New Chemopreventive Agents Master Agreement Pool and who wish to be considered for inclusion should consult the NCI Research Contracts Branch website at http://rcb.nci.nih.gov/ under "Current Request for Proposals" scroll to Master Agreement Announcements and refer to RFP No. N01-CN-85080-39. The duration of the current Phase I Master Agreement Pool is 2/1998 through 2/15/2003. Please see the Master Agreement Announcement for due dates of proposals and further instructions on how to become a member of the Phase I Clinical Trials of New Chemoprevention Agents Master Agreement Pool. It is anticipated that this RFP No. N01-CN-25025-76 will be available around April 18, 2002. It is the offeror's responsibility to request a copy of the RFP. Point of contact: Cynthia D. Washington, Contract Specialist, NCI, RCB, PCPSS; 6120 Executive Boulevard, Executive Plaza South, Room 6002, Rockville, MD 20852; Email address: contact@example.gov; Telephone: +1 (555) 000-0000; Fax +1 (555) 000-0000. All requests should reference the RFP No. N01-CN-25025-76. No collect calls will be accepted. Numbered Note 26 - Based upon market research, the Government is not using the policies contained in Part 12, Acquisition of Commercial Items, in its solicitation for the described supplies or services. However, interested persons may identify to the contracting officer their interest and capability to satisfy the Government's requirement with a commercial item within 15 days of this notice.