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Advanced Confocal and 3D-STED Microscope Supply

Active
Federal

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

General Info

Agency

Department Of Health And Human Services → National Institutes Of Health NichdView Agency

NAICS

334516 - Analytical Laboratory Instrument ManufacturingView NAICS

Place of Performance

Bethesda, MD, 20892, USA

Set-Aside

NONE

Documents

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health Nichd
ContactsNo contacts available
OfficeN/A
Organization / Agency
Department Of Health And Human Services → National Institutes Of Health Nichd
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ContactsNo contact information available

Full Description

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Supply of a Leica Stellaris microscope system with confocal, 3D-STED, FLIM, and spectral multiplexing capabilities to replace an outdated system at the NHLBI Light Microscopy Core.

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More opportunities from Department Of Health And Human Services → National Institutes Of Health Nichd

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Leica Microsystems Stellaris Microscope System with Confocal 3D StedThe National Institutes of Health, National Heart, Lung and Blood Institute, is seeking to acquire a single, integrated Stellaris Microscope System with advanced confocal, 3D-STED, fluorescence lifetime imaging (FLIM), and high-plex spectral multiplexing capabilities under a Firm-Fixed-Price Purchase Order. This acquisition is an open market competition with no set-aside, targeting a state-of-the-art laser-scanning platform to replace a 12-year-old Leica SP8 microscope, which will be traded in with removal, packing, and site cleanup included as part of the delivery. The system must support white light laser excitation from 440–790 nm with an acousto-optical beam splitter, prism-based spectral detection spanning 400–850 nm, and at least five Hybrid (HyD) detectors optimized for the full emission range. It must include fully integrated 3D-STED super-resolution with pulsed depletion lasers at 589 nm and 775 nm, time-gated detection for background suppression, and motorized correction collars compatible with oil, glycerin, and water immersion objectives, including a new 86x water-immersion objective chromatically corrected across the full excitation range. FLIM functionality must utilize time-correlated single photon counting with sub-100 picosecond timing resolution and support multi-exponential fitting, lifetime-based unmixing, and integrated enhancement of STED resolution. The platform must enable simultaneous imaging and spectral unmixing of fifteen or more fluorophores using integrated software tools for multiplex panel design. Scanning must allow fast switching between galvo and resonant modes, and the white light laser must include a pulse picker for optimizing FLIM and related applications. All components must operate as a unified, manufacturer-supported system with full software integration. The vendor must deliver, install, and commission the system at the NIH main campus in Bethesda, Maryland, and provide comprehensive user training, a manufacturer warranty, and ongoing service. Quotations must be submitted as a three-volume package: Volume I includes a technical response detailing the system configuration with point-by-point alignment to all salient requirements; Volume II lists up to three relevant past performance contracts; and Volume III provides a complete, itemized price quote inclusive of shipping, installation, training, warranty, and all other associated costs. Any offer of an “equal” product must clearly demonstrate equivalency through detailed technical documentation, including specifications, literature, and a crosswalk
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