This Pre-Solicitation opportunity from Department Of Health And Human Services was posted on May 20, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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Chemistry Support for the DTT

Closed

75N94026R00002Federal

Submission Closed06/04/2026, 07:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541715

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in 7 months

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AI Contract Overview

The National Institute of Environmental Health Sciences (NIEHS) has issued a presolicitation notice (Notice ID 75N94026R00002) for Chemistry Support services to assist the Division of Translational Toxicology (DTT). This notice, released as a Request for Information (RFI) and Sources Sought Notice (SSN), seeks input from qualified organizations capable of providing a wide range of chemistry research and development services critical to toxicological studies. The objective is to support NIEHS’s efforts in understanding how environmental factors influence human disease development and progression, focusing on toxicology involving chemical, physical, and biological agents through both in vitro and in vivo models. The anticipated contract, to be awarded under a full and open competition, is intended as a cost-plus-fixed-fee type covering a 12-month base period with nine option years beginning in early 2027. Proposals will be due around July 20, 2026. The scope encompasses comprehensive chemistry support activities including procurement, handling, and detailed characterization of test articles ranging from single chemicals to complex mixtures, formulation for dosing, concentration determination, analysis of biological and environmental matrices, omics analyses, and ADME/TK studies. The contract will require management of quality, safety, and compliance plans such as IT Security, Health and Safety, and Quality Management Plans, along with adherence to applicable regulations and standards, including FDA Good Laboratory Practices (GLP), AAALAC accreditation, and IACUC protocols for animal research. The contractor must provide personnel, facilities, and equipment to fulfill assignments in accordance with the DTT Chemistry Specifications, ensuring rigorous inspection, acceptance, and reporting practices. Key personnel including Principal Investigators must be direct employees of the contractor, emphasizing organizational control and conflict-of-interest mitigation. While no formal solicitation or award criteria are defined at this stage, the government encourages all capable businesses, across all socioeconomic categories and size statuses under NAICS code 541715, to submit comments, RFI responses, and business information as part of the market research phase to inform the upcoming formal procurement.

General Info

NIEHS seeks chemistry support for toxicology research, 12-month base, nine option years, proposals due July 2026.

Agency

Department Of Health And Human Services → National Institutes Of Health Nichd

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology) View NAICS

Place of Performance

MD, USA

Set-Aside

NONE

Documents

(1)

RFI and Sources Sought Notice for Chemistry Support NIEHS 75N94026R00002

PDF•29 pages•rfi

AI Contract Breakdown

Uniform Contract Format

Timeline

PhaseClosed

PostedMay 20

Presolicitation

Response DeadlineJun 4

Deadline has passed

Submission Closed

06/04/2026, 07:00:00 PM UTC

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Organization & Contact Information

AgencyDepartment Of Health And Human Services → National Institutes Of Health Nichd

Contacts2 people available

OfficeBETHESDA, MD, 20817, USA

Organization / Agency

Department Of Health And Human Services → National Institutes Of Health Nichd

Office AddressBETHESDA, MD, 20817, USA

Contacts

BANK SARAH N

contact@example.gov

+1 (555) 000-0000

SCHAUPP LISA L

contact@example.gov

Full Description

PRE-SOLICITATION NOTICE

Notice ID: 75N94026R00002

Title: Chemistry Support for the Division of Translational Toxicology (DTT)

Description:

This notice is related to a Request for Information (RFI)/Sources Sought Notice (SSN), 75N94026R00002, released on February 17, 2026. This acquisition is a full and open competition.

This notice is issued on behalf of the National Institute of Environmental Health Sciences (NIEHS) by the Office of Acquisition and Logistics Management (OALM), OD, Research and Development and Professional Services- Division B. This presolicitation notice is being published in accordance with the Federal Acquisition Regulations (FAR) Part 5.101. This is a Presolicitation Notice in advance of the Request for Proposal (RFP). The Government is not committed to award a contract pursuant to this announcement.

The RFP, 75N94026R00002, detailing the specifics of the project, as well as information pertinent to the development of an Offeror's proposal, will be available electronically within 15 calendar days of this notice and may be accessed through SAM.gov (point of federal distribution). No paper solicitation is available. Potential Offerors are responsible for downloading the solicitation and for routinely checking the SAM.gov for any solicitation amendments issued by the Government. Proposals will be due on or about July 20, 2026. It is anticipated that a single cost plus fixed-fee contract award will be made for a 12-month base contract with nine (9) option periods beginning on or about January 18, 2027.

This is a Research and Development contract requirement entitled, “Chemistry Support for the DTT”. This is NOT an NIH grant opportunity.

The National Institute of Environmental Health Sciences (NIEHS) seeks a contractor to address the present and anticipated future needs of NIEHS’s intramural Division of Translational Toxicology (DTT). The need is to continue to conduct research to discover how the environment influences the development and progression of human disease to promote healthier lives and to better understand how factors in the environment may impact human health. In addition, this requirement should produce information to predict adverse human health effects from chemical exposures.

DTT uses traditional and cutting-edge approaches to better understand how factors in the environment may impact human health. Such approaches include the conduct of toxicology studies on chemical, physical and biological agents, as well as non-chemical stressors, using in vitro and in vivo models of health and disease.

The contractor shall provide a broad range of chemistry R&D services in support of DTT and/or NTP research programs. Chemistry support is needed for a diverse range of test articles studied at DTT and/or NTP. The test articles can vary from a single chemical to a complex mixture with a wide variety of physical and chemical properties. The chemistry support required includes test article procurement and handling, comprehensive characterization of test articles, formulation of test article in a suitable vehicle to be administered in test models and determining concentration, analysis of biological matrices for concentration of test articles and metabolites, omics analyses of biological and environmental matrices, in vitro assays, absorption, distribution, metabolism, and excretion/toxicokinetic (ADME/TK) studies, In Vitro studies, and medium to high throughput chemistry support for in vitro toxicity screening are required for the successful execution of these studies.

All qualified organizations are encouraged to respond with a contract proposal.

Primary Point of Contact:

Sarah Bank

Contracting Officer

Email: Sarah.Bank@nih.gov