This Solicitation opportunity from Department Of Health And Human Services was posted on September 3, 2026. The submission period has ended. Browse the details below for market research, or find similar active opportunities.

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Chemistry Research for the Division of Translational Toxicology (DTT)

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75N94026R00002Federal

Submission Closed09/14/2026, 08:00:00 PM UTC

Contract Overview

Solicitation details, issuing organization, response deadlines, documents, and interested companies for this government contract opportunity.

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NAICS: 541715

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POSTED

1 day ago

DEADLINE

in 16 days

AI Contract Overview

Solicitation 75N94026R00002 is a request for proposals to provide comprehensive chemistry research services for the National Institute of Environmental Health Sciences (NIEHS), specifically supporting the Division of Translational Toxicology (DTT) and the National Toxicology Program (NTP). The contract is structured as a multiple-year cost-reimbursement type completion contract with a base period from January 18, 2027, to January 17, 2008, and nine subsequent 12-month option periods, potentially extending the performance through July 17, 2037. The scope of work encompasses eight functional areas: Logistics and Handling, Characterization, Formulation, Biosample Analysis, Special Studies, Animal Studies, Omics, and In Vitro Assays. All research must adhere to DTT Chemistry Specifications, FDA Good Laboratory Practices (21 CFR 58), EPA Quality Management Plans, and USP XXIII standards. The award process emphasizes best value, utilizing a tradeoff approach where technical experience and past performance are significantly more important than cost. Proposals are evaluated using adjectival ratings, and a minimum small business participation of 5% of the total contract value is required to avoid a deficiency. Key personnel requirements include a Principal Investigator and a Deputy PI. Offerors must provide verification of IACUC approval for any work involving live vertebrate animals and submit a Health and Safety Chemical Hygiene Plan. Proposals must be submitted electronically via the NIH eCPS website, with the final deadline set for September 14, 2026. Inspection and acceptance of services will be conducted at Research Triangle Park, North Carolina.

General Info

NIEHS seeks chemistry support for toxicology research, 12-month base, nine option years, proposals due July 2026.

Agency

Department Of Health And Human Services → National Institutes Of Health NichdView Agency

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)View NAICS

Place of Performance

MD, USA

Set-Aside

NONE

Documents

(21)

Additional Proposal Instructions and Evaluation Criteria Amendment 01

PDF•64 pages•amendment

Additional Proposal Instructions, Evaluation Criteria, and Sub-Attachments

PDF•52 pages•evaluation-criteria

Amendment 01 - RFP 75N94026R00002 Chemistry Support for DTT

PDF•amendment

Amendment 02 to RFP 75N94026R00002 Chemistry Support DTT

PDF•2 pages•amendment

Amendment 3

PDF•2 pages•amendment

Amendment 4 – RFP 75N94026R00002 Chemistry Support for DTT

PDF•2 pages•amendment

Amendment 5 – RFP 75N94026R00002 Chemistry Support for DTT

PDF•2 pages•amendment

Attachment 13 Breakdown of Proposed Estimated Costs Business Template

XLSX•28 pages•cost-proposal-template

Attachment 24 - Additional Proposal Instructions and Evaluation Criteria

PDF•64 pages•evaluation-criteria

Breakdown of Proposed Estimated Costs Business Template

XLSX•28 pages•cost-proposal-template

RFI and Sources Sought Notice for Chemistry Support NIEHS 75N94026R00002

PDF•29 pages•rfi

RFP 75N94026R00002 Chemistry Research for Division of Translational Toxicology

PDF•64 pages•rfp

RFP 75N94026R00002 Chemistry Research for Division of Translational Toxicology

PDF•61 pages•rfp

RFP 75N94026R00002 - Chemistry Research for DTT

PDF•128 pages•rfp

RFP 75N94026R00002 Chemistry Research for the DTT

PDF•128 pages•rfp

RFP 75N94026R00002 Chemistry Research for the DTT Amendment 01

PDF•128 pages•rfp

RFP 75N94026R00002 Chemistry Research for the DTT Amendment 02

PDF•128 pages•rfp

RFP 75N94026R00002 Chemistry Research for the DTT - Q&A Amendment 2

PDF•15 pages•amendment

Section K Representations, Certifications, and Other Statements of Offerors

PDF•8 pages•certifications

Attachment E NIEHS Level of Effort Worksheet

XLSX•14 pages•level-of-effort-worksheet

Attachment E NIEHS Level of Effort Worksheet

XLSX•14 pages•cost-estimate-worksheet

AI Contract Breakdown

Uniform Contract Format

Timeline

4 updates

PhaseClosed

PostedFeb 17

Sources Sought

Type ChangedMay 20

Sources Sought → Presolicitation

Type ChangedJul 28

Presolicitation → Solicitation

Notice updatedAug 4

Notice details unchanged. Attachments may have changed.

Deadline changedAug 14

Response deadline changed from Sep 11, 2026 to Sep 14, 2026.

Notice updatedAug 17

Notice details unchanged. Attachments may have changed.

Notice updatedAug 25

Notice details unchanged. Attachments may have changed.

Response DeadlineSep 14

Deadline has passed

Submission Closed

09/14/2026, 08:00:00 PM UTC

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Organization & Contact Information

AgencyDepartment Of Health And Human Services → National Institutes Of Health Nichd

Contacts2 people available

OfficeBETHESDA, MD, 20817, USA

Organization / Agency

Department Of Health And Human Services → National Institutes Of Health Nichd

View Agency Profile

Office AddressBETHESDA, MD, 20817, USA

Contacts

BANK SARAH N

contact@example.gov

+1 (555) 000-0000

SCHAUPP LISA L

contact@example.gov

Full Description

The mission of National Institute of Environmental Health Sciences (NIEHS) is to discover how the environment affects people to promote healthier lives. The Division of Translational Toxicology (DTT) is an intramural division at NIEHS, and DTT scientists use a variety of traditional and cutting-edge approaches to better understand how factors in our environment may impact our health. One of DTT's goals is to lead the transformation of toxicology through the development and application of innovative tools and strategies. This contract will provide required chemistry research at each step of the DTT toxicological evaluation process.

This acquisition is to conduct Chemistry Research for NIEHS, Division of Translational Toxicology (DTT) and National Toxicology Program (NTP). The type and extent of chemistry research support provided will be specific to DTT and NTP research needs. Program management procedures and chemistry technical activities will be provided under eight (8) Functional Areas: Logistics and Handling, Characterization, Formulation, Biosample Analysis, Special Studies, Animal Studies, Omics and In Vitro Assays.

Specifications for the Conduct of Chemistry Activities for Toxicology Research Performed by the Division of Translational Toxicology at the National Institute of Environmental Health Sciences (DTT Chemistry Specifications):

https://ntp.niehs.nih.gov/data/research/chemistry/rfp