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Single Source Competition for Continuation of Understanding and Targeting the Pathophysiology of Youth-Onset Type 2 Diabetes Clinical Centers (U01 Clinical Trial Not Allowed)

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The National Institutes of Health is issuing a single-source solicitation to continue the DISCOVERY of Risk Factors for Type 2 Diabetes in Youth Study. This multi-center longitudinal consortium operates across 19 clinical sites to investigate the biological mechanisms and risk factors associated with youth-onset type 2 diabetes, specifically focusing on high-risk youth during early puberty. The contract supports the Biostatistics Research Center, which acts as the central coordinating hub for the project. This center is responsible for managing data, ensuring quality assurance, overseeing statistical design and analysis, and coordinating protocol implementation across all sites to maintain the integrity of the longitudinal dataset and achieve the study's scientific objectives.

General Info

Continue support for youth type 2 diabetes research across 19 sites with centralized data coordination.

Agency

Department Of Health And Human Services → National Institutes Of Health

NAICS

541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)

Place of Performance

Not specified

Set-Aside

NONE

Documents

0

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Organization & Contact Information

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AgencyDepartment Of Health And Human Services → National Institutes Of Health
Contacts1 person available
OfficeUSA
Organization / AgencyDepartment Of Health And Human Services → National Institutes Of Health
Office AddressUSA
Contacts
Division of Diabetes Endocrinology and Metabolic Diseases
contact@example.gov

Full Description

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The DISCOVERY of Risk Factors for Type 2 Diabetes in Youth Study is a multi-center longitudinal consortium conducted across 19 clinical sites to identify risk factors and biological mechanisms driving progression to youth-onset type 2 diabetes. The study is actively recruiting and following early pubertal youth at high risk for the disease with longitudinal follow-up currently underway. The current Biostatistics Research Center (BRC) serves as the consortium's central coordinating center, managing protocol implementation, data management, quality assurance, statistical design and analysis, and inter-site and consortium-wide coordination.  The BRC has established the robust infrastructure and standardized processes required to support the study and preserve the integrity of the longitudinal dataset. 

The purpose of this single-source solicitation is to support completion of the scientific objectives of the ongoing DISCOVERY clinical consortium.

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